Comparing WP_012400935.1 NCBI__GCF_000020045.1:WP_012400935.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 15 hits to proteins with known functional sites (download)
1u8aA Crystal structure of mycobacterium tuberculosis shikimate kinase in complex with shikimate and adp at 2.15 angstrom resolution (see paper)
34% identity, 47% coverage: 144:293/317 of query aligns to 6:151/163 of 1u8aA
Sites not aligning to the query:
3bafA Crystal structure of shikimate kinase from mycobacterium tuberculosis in complex with amp-pnp
33% identity, 47% coverage: 144:293/317 of query aligns to 6:153/165 of 3bafA
2dfnA Structure of shikimate kinase from mycobacterium tuberculosis complexed with adp and shikimate at 1.9 angstrons of resolution (see paper)
33% identity, 47% coverage: 144:293/317 of query aligns to 6:153/165 of 2dfnA
Sites not aligning to the query:
1we2A Crystal structure of shikimate kinase from mycobacterium tuberculosis in complex with mgadp and shikimic acid (see paper)
33% identity, 47% coverage: 144:293/317 of query aligns to 6:153/165 of 1we2A
2iywA Shikimate kinase from mycobacterium tuberculosis in complex with mgatp, open lid (conf. B) (see paper)
32% identity, 51% coverage: 144:305/317 of query aligns to 6:165/178 of 2iywA
2iyvA Shikimate kinase from mycobacterium tuberculosis in complex with adp, open lid (conf. B) (see paper)
32% identity, 51% coverage: 144:305/317 of query aligns to 6:165/179 of 2iyvA
4bqsA Crystal structure of mycobacterium tuberculosis shikimate kinase in complex with adp and a shikimic acid derivative. (see paper)
32% identity, 51% coverage: 144:305/317 of query aligns to 6:165/169 of 4bqsA
2iyyA Shikimate kinase from mycobacterium tuberculosis in complex with shikimate-3-phosphate and so4 (see paper)
32% identity, 51% coverage: 144:305/317 of query aligns to 6:165/169 of 2iyyA
1zyuA Crystal structure of mycobacterium tuberculosis shikimate kinase in complex with shikimate and amppcp at 2.85 angstrom resolution (see paper)
32% identity, 51% coverage: 144:305/317 of query aligns to 6:165/168 of 1zyuA
P10880 Shikimate kinase 2; SK 2; Shikimate kinase II; SKII; EC 2.7.1.71 from Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi) (see paper)
30% identity, 47% coverage: 142:291/317 of query aligns to 5:155/173 of P10880
Sites not aligning to the query:
1e6cA K15m mutant of shikimate kinase from erwinia chrysanthemi (see paper)
29% identity, 47% coverage: 142:291/317 of query aligns to 5:155/170 of 1e6cA
2shkB The three-dimensional structure of shikimate kinase from erwinia chrysanthemi complexed with adp (see paper)
30% identity, 47% coverage: 142:291/317 of query aligns to 5:145/162 of 2shkB
Sites not aligning to the query:
1shkA The three-dimensional structure of shikimate kinase from erwinia chrysanthemi (see paper)
33% identity, 33% coverage: 142:245/317 of query aligns to 5:106/158 of 1shkA
Sites not aligning to the query:
6hqvA Pentafunctional arom complex from chaetomium thermophilum (see paper)
33% identity, 31% coverage: 125:223/317 of query aligns to 824:927/1555 of 6hqvA
Sites not aligning to the query:
P07547 Pentafunctional AROM polypeptide; EC 4.2.3.4; EC 2.5.1.19; EC 2.7.1.71; EC 4.2.1.10; EC 1.1.1.25 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 2 papers)
32% identity, 28% coverage: 136:224/317 of query aligns to 859:949/1583 of P07547
Sites not aligning to the query:
>WP_012400935.1 NCBI__GCF_000020045.1:WP_012400935.1
MNQTYSADASLAQRANEEAPKAEREERDPFLTAMGERVRLLRARRGMTRKTLASETGLSE
RHLANLESGVGNASVLVLRQIAATLNCPLAEVIGDETTSSAEWLLIRELLHGRDQAALQR
ARVALSEMFAQAPRDPHRKDRIALIGLRGAGKSTLGRMLAQERKVPFIEITKVIQQMAGC
PPSEIHSLYGASAYRRYEQRALEAVIGEHERAVIASPGGLVSEPATFNALLAHCFTVWLQ
ASPEEHMRRVVAQGDLRPMSGNKEAMEDLKRILAGRGELYNRADMIFDTSERTLADAYLQ
LRDRLAARLAAELGDET
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory