SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_012403201.1 NCBI__GCF_000020045.1:WP_012403201.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

P07117 Sodium/proline symporter; Proline carrier; Proline permease; Propionate transporter from Escherichia coli (strain K12) (see 4 papers)
21% identity, 74% coverage: 8:369/491 of query aligns to 5:370/502 of P07117

query
sites
P07117
N
 
T
P
 
P
V
 
M
A
 
L
M
 
V
T
 
T
V
 
F
F
 
C
I
 
V
A
 
Y
F
 
I
F
 
F
V
 
G
L
 
M
V
 
I
T
 
-
V
 
L
L
 
I
G
 
G
F
 
F
I
 
I
A
 
A
A
 
W
R
 
R
W
 
-
K
 
-
A
 
-
G
 
-
D
 
S
L
 
T
T
 
K
Q
 
N
L
 
F
H
 
D
E
 
D
W
 
Y
G
 
I
L
 
L
G
 
G
G
 
G
R
 
R
Q
 
S
F
 
L
G
 
G
T
 
P
V
 
F
I
 
V
S
 
T
W
 
A
F
 
L
L
 
S
V
 
A
G
 
G
G
 
A
D
 
S
F
 
D
Y
 
M
T
 
S
A
 
G
Y
 
W
T
 
L
V
 
L
I
 
M
A
 
G
V
 
L
P
 
P
A
 
G
L
 
A
V
 
V
Y
 
F
S
 
L
V
 
S
G
 
G
-
 
I
A
 
S
Y
 
E
G
 
S
F
 
W
F
 
I
A
 
A
L
 
I
P
 
G
Y
 
L
T
 
T
I
 
L
I
 
G
V
 
A
Y
 
W
P
 
I
F
 
N
V
 
W
F
 
K
A
 
L
V
 
V
M
 
A
P
 
G
K
 
R
L
 
L
W
 
R
-
 
V
K
 
H
I
 
T
A
 
E
H
 
Y
A
 
N
K
 
N
N
 
N
H
 
A
I
 
L
T
 
T
A
 
L
A
 
P
D
 
D
Y
 
Y
V
 
F
H
 
T
G
 
G
E
 
R
Y
 
F
G
 
E
G
 
D
K
 
K
W
 
S
F
 
R
P
 
I
A
 
L
A
 
R
V
 
I
-
 
I
-
 
S
A
 
A
L
 
L
T
 
V
G
 
I
I
 
L
V
 
L
A
 
F
T
 
F
M
 
T
P
 
I
Y
 
Y
I
 
C
A
 
A
L
 
S
Q
 
G
L
 
I
V
 
V
-
 
A
G
 
G
M
 
A
Q
 
R
V
 
L
V
 
F
I
 
E
K
 
S
G
 
T
L
 
F
G
 
G
V
 
M
S
 
S
G
 
Y
E
 
E
A
 
T
P
 
A
L
 
L
I
 
W
I
 
A
A
 
G
F
 
A
I
 
A
I
 
A
L
 
T
A
 
I
L
 
L
Y
 
Y
T
 
T
Y
 
F
T
 
I
S
 
G
G
 
G
L
 
F
R
 
L
A
 
A
P
 
V
A
 
S
M
 
W
I
 
T
A
 
D
F
 
T
V
 
V
K
 
Q
-
 
A
D
 
S
I
 
L
M
 
M
I
 
I
Y
 
F
I
 
A
V
 
L
V
 
I
I
 
L
A
 
T
A
 
P
I
 
V
W
 
-
L
 
I
I
 
V
P
 
I
V
 
I
K
 
S
L
 
V
G
 
G
G
 
G
Y
 
F
G
 
G
H
 
D
V
 
S
F
 
L
D
 
E
A
 
V
A
 
I
D
 
K
Q
 
Q
Y
 
-
F
 
-
Q
 
-
A
 
-
K
 
K
G
 
S
G
 
I
A
 
E
T
 
N
G
 
V
I
 
D
I
 
M
L
 
L
K
 
K
P
 
G
T
 
L
Q
 
N
F
 
F
T
 
V
A
 
A
Y
 
I
A
 
I
S
 
S
L
 
L
A
 
-
L
 
M
G
 
G
S
 
W
A
 
G
L
 
L
A
 
G
A
 
Y
F
 
F
M
 
G
Y
 
Q
P
 
P
H
 
H
T
 
I
M
 
L
T
 
A
A
x
R
V
 
F
L
 
M
S
 
A
S
 
A
S
 
D
S
 
S
A
 
H
K
 
H
T
 
S
-
 
I
V
 
V
R
 
H
K
 
A
N
 
R
A
 
R
I
 
I
F
 
S
L
 
M
P
 
T
A
 
W
Y
 
M
T
 
I
L
 
L
L
x
C
L
 
L
G
 
A
L
 
G
I
 
A
A
 
V
L
 
A
L
 
V
G
 
G
Y
 
F
M
 
F
A
 
G
I
 
I
A
 
A
-
 
Y
-
 
F
-
 
N
-
 
D
-
 
H
-
 
P
-
 
A
-
 
L
A
 
A
G
 
G
V
 
A
H
 
V
V
 
N
K
 
Q
S
 
N
A
 
A
S
 
E
D
 
R
I
 
V
V
 
F
P
 
I
A
 
E
L
 
L
F
 
A
G
 
Q
T
 
I
L
 
L
F
 
F
P
 
N
S
 
P
W
 
W
F
 
I
V
 
A
G
 
G
F
 
I
A
 
L
A
 
L
A
 
S
A
 
A
I
 
I
A
 
L
I
 
A
S
 
A
A
 
V
L
 
M
V
 
S
P
 
T
A
 
L
A
 
S
I
x
C
M
 
Q
S
 
L
I
 
L
G
 
V
A
x
C
A
 
S
N
 
S
L
 
A
F
 
I
T
 
T
R
 
E
N
 
D
L
 
L
W
 
Y
R
 
K
P
 
A
L
 
F
V
 
L
S
 
R
P
 
K
N
 
H
M
 
A
G
 
S
S
 
Q
A
 
K
Q
 
E

Sites not aligning to the query:

Query Sequence

>WP_012403201.1 NCBI__GCF_000020045.1:WP_012403201.1
MSDLNPVNPVAMTVFIAFFVLVTVLGFIAARWKAGDLTQLHEWGLGGRQFGTVISWFLVG
GDFYTAYTVIAVPALVYSVGAYGFFALPYTIIVYPFVFAVMPKLWKIAHAKNHITAADYV
HGEYGGKWFPAAVALTGIVATMPYIALQLVGMQVVIKGLGVSGEAPLIIAFIILALYTYT
SGLRAPAMIAFVKDIMIYIVVIAAIWLIPVKLGGYGHVFDAADQYFQAKGGATGIILKPT
QFTAYASLALGSALAAFMYPHTMTAVLSSSSAKTVRKNAIFLPAYTLLLGLIALLGYMAI
AAGVHVKSASDIVPALFGTLFPSWFVGFAAAAIAISALVPAAIMSIGAANLFTRNLWRPL
VSPNMGSAQEASTAKIVSLVVKFGALLFIVFLPTQYAIDLQLLGGVWILQIFPAIVFSLY
TRRLNTPGLFLGWLVGIVVGTGLAISQGLKPVFALHVGASTWPLYIGLIALVVNIVVTFI
VSMTTPKRVHA

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory