Comparing WP_012407607.1 NCBI__GCF_000020025.1:WP_012407607.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5ktlA Dihydrodipicolinate synthase from the industrial and evolutionarily important cyanobacteria anabaena variabilis. (see paper)
83% identity, 100% coverage: 1:294/294 of query aligns to 2:295/295 of 5ktlA
5ud6C Crystal structure of dhdps from cyanidioschyzon merolae with lysine bound
57% identity, 96% coverage: 4:285/294 of query aligns to 4:289/299 of 5ud6C
P9WP25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
42% identity, 99% coverage: 4:294/294 of query aligns to 12:299/300 of P9WP25
5j5dA Crystal structure of dihydrodipicolinate synthase from mycobacterium tuberculosis in complex with alpha-ketopimelic acid (see paper)
42% identity, 99% coverage: 4:294/294 of query aligns to 9:296/297 of 5j5dA
1xxxA Crystal structure of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis (see paper)
42% identity, 99% coverage: 4:294/294 of query aligns to 8:295/296 of 1xxxA
Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
43% identity, 99% coverage: 4:294/294 of query aligns to 2:294/294 of Q9X1K9
1o5kA Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
43% identity, 99% coverage: 4:294/294 of query aligns to 3:295/295 of 1o5kA
3l21B The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis - dhdps- a204r
42% identity, 99% coverage: 4:294/294 of query aligns to 7:294/295 of 3l21B
4fhaA Structure of dihydrodipicolinate synthase from streptococcus pneumoniae,bound to pyruvate and lysine
42% identity, 95% coverage: 7:284/294 of query aligns to 10:286/307 of 4fhaA
2atsA Dihydrodipicolinate synthase co-crystallised with (s)-lysine
40% identity, 99% coverage: 4:294/294 of query aligns to 2:292/292 of 2atsA
P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Escherichia coli (strain K12) (see 7 papers)
40% identity, 99% coverage: 4:294/294 of query aligns to 2:292/292 of P0A6L2
4pfmA Shewanella benthica dhdps with lysine and pyruvate
42% identity, 96% coverage: 8:290/294 of query aligns to 7:289/295 of 4pfmA
5t25A Kinetic, spectral and structural characterization of the slow binding inhibitor acetopyruvate with dihydrodipicolinate synthase from escherichia coli.
40% identity, 99% coverage: 4:294/294 of query aligns to 3:293/293 of 5t25A
3i7sA Dihydrodipicolinate synthase mutant - k161a - with the substrate pyruvate bound in the active site. (see paper)
40% identity, 99% coverage: 4:294/294 of query aligns to 2:292/292 of 3i7sA
3s8hA Structure of dihydrodipicolinate synthase complexed with 3- hydroxypropanoic acid(hpa)at 2.70 a resolution
43% identity, 96% coverage: 8:288/294 of query aligns to 6:291/292 of 3s8hA
3puoA Crystal structure of dihydrodipicolinate synthase from pseudomonas aeruginosa(psdhdps)complexed with l-lysine at 2.65a resolution (see paper)
43% identity, 96% coverage: 8:288/294 of query aligns to 6:291/292 of 3puoA
7kg2A Dihydrodipicolinate synthase (dhdps) from c.Jejuni, h59k mutant with pyruvate bound in the active site and l-histidine bound at the allosteric site
41% identity, 97% coverage: 8:293/294 of query aligns to 8:293/296 of 7kg2A
4m19A Dihydrodipicolinate synthase from c. Jejuni with pyruvate bound to the active site and lysine bound to allosteric site (see paper)
41% identity, 97% coverage: 8:293/294 of query aligns to 8:293/296 of 4m19A
4dxvA Crystal structure of dihydrodipicolinate synthase from acinetobacter baumannii complexed with mg and cl ions at 1.80 a resolution
38% identity, 98% coverage: 8:294/294 of query aligns to 6:291/291 of 4dxvA
3u8gA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with oxalic acid at 1.80 a resolution
38% identity, 98% coverage: 8:294/294 of query aligns to 6:291/291 of 3u8gA
>WP_012407607.1 NCBI__GCF_000020025.1:WP_012407607.1
MGDFGNVLTAMITPFKADGSVDYGVAAELAVHLANNGTDTLVMCGTTGESPTLSWDEEYQ
LFVEVLQSVAGKAKVIAGCGSNSTKEAIAATQKASKIGVHGSLQVVPYYNKPPQAGLEAH
FQAIAQACPDLPLLLYNVPGRTGQNLQPETVARLAEVSNIVGIKESTGSIDQASEIRRLT
PKEFHIYSGDDYMTLPLLAIGAKGVVSVASHLVGNQLQQMIQAFSAGKIEVARDIHLQLF
PLFKALFLTSNPIPVKKALKLQGWEVGSTRPPLCEADLEVSQKLEGVLKELSLI
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory