Comparing WP_012466736.1 NCBI__GCF_000020465.1:WP_012466736.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
2vatA Crystal structure of deacetylcephalosporin c acetyltransferase in complex with coenzyme a (see paper)
42% identity, 92% coverage: 21:349/358 of query aligns to 18:347/347 of 2vatA
2vavB Crystal structure of deacetylcephalosporin c acetyltransferase (dac- soak) (see paper)
42% identity, 92% coverage: 21:349/358 of query aligns to 19:349/350 of 2vavB
5w8oB Homoserine transacetylase metx from mycobacterium hassiacum (see paper)
43% identity, 92% coverage: 15:345/358 of query aligns to 3:340/346 of 5w8oB
P45131 Homoserine O-acetyltransferase; HAT; Homoserine O-trans-acetylase; Homoserine transacetylase; HTA; EC 2.3.1.31 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
39% identity, 91% coverage: 19:345/358 of query aligns to 12:353/358 of P45131
Sites not aligning to the query:
6ioiA Crystal structure of homoserine o-acetyltransferase in complex with coa from mycobacterium smegmatis atcc 19420 (see paper)
39% identity, 94% coverage: 7:344/358 of query aligns to 5:359/366 of 6ioiA
6iohA Crystal structure of homoserine o-acetyltransferase in complex with homoserine from mycobacterium smegmatis atcc 19420 (see paper)
39% identity, 94% coverage: 7:344/358 of query aligns to 5:359/375 of 6iohA
8f2lA Crystal structure of mycobacterium tuberculosis homoserine transacetylase in complex with l-homoserine (see paper)
38% identity, 90% coverage: 24:345/358 of query aligns to 21:359/367 of 8f2lA
7rytB Crystal structure of mycobacterium tuberculosis acetylated homoserine transacetylase with coenzyme a (see paper)
38% identity, 90% coverage: 24:345/358 of query aligns to 21:359/368 of 7rytB
6puxA Homoserine transacetylase metx from mycobacterium tuberculosis (see paper)
38% identity, 90% coverage: 24:345/358 of query aligns to 22:360/366 of 6puxA
Q6FEQ3 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
38% identity, 93% coverage: 15:346/358 of query aligns to 16:371/387 of Q6FEQ3
Q10341 Serine O-succinyltransferase; SST; EC 2.3.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
40% identity, 73% coverage: 13:275/358 of query aligns to 82:359/504 of Q10341
Sites not aligning to the query:
D2Z028 L-serine/homoserine O-acetyltransferase; Homoserine O-trans-acetylase; EC 2.3.1.30; EC 2.3.1.31 from Streptomyces lavendulae (see paper)
35% identity, 96% coverage: 5:346/358 of query aligns to 2:369/374 of D2Z028
>WP_012466736.1 NCBI__GCF_000020465.1:WP_012466736.1
MRDYRELISEKTRYFVSQKPFATESGGVLPELRIAYRTWGKPDQEKSNVILICHALTGSA
DADVWWDGMFAEGGAFDEAKDFIICCNVLGSCYGTTGPLSLNPLTGRHYGPDFPRITIRD
MVHAQRLLLDEFGIDRIRLVVGASLGGMQVLEWGFLYPKMVQAMMPMGVSGRHSSWCIAQ
SEAQRQAIYADRDWNGGWYAADCPPASGLAAARMMAMCSYRSFENFQSRFGRDVQDDGLF
RVESYLHYQGRKLVDRFDANTYVTLTKAMDMHDLSRGRGVYEEVLGSLQIPVEILSIISD
VLYPKEEQEELGRLMQHSRVIYLDEPYGHDAFLIDVEKVGRMVREFKDERAVKAHSAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory