Comparing WP_012470203.1 NCBI__GCF_000020385.1:WP_012470203.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
4wjiA Crystal structure of cyclohexadienyl dehydrogenase from sinorhizobium meliloti in complex with NADP and tyrosine
43% identity, 98% coverage: 7:288/288 of query aligns to 5:287/293 of 4wjiA
3gggD The crystal structure of a. Aeolicus prephenate dehydrogenase in complex with tyrosine and NAD+ (see paper)
41% identity, 96% coverage: 11:287/288 of query aligns to 18:293/293 of 3gggD
3ggoA Crystal structure of prephenate dehydrogenase from a. Aeolicus with hpp and nadh (see paper)
41% identity, 96% coverage: 11:287/288 of query aligns to 10:285/285 of 3ggoA
3ggpA Crystal structure of prephenate dehydrogenase from a. Aeolicus in complex with hydroxyphenyl propionate and NAD+ (see paper)
41% identity, 96% coverage: 11:287/288 of query aligns to 10:285/286 of 3ggpA
6u60B Crystal structure of prephenate dehydrogenase tyra from bacillus anthracis in complex with NAD and l-tyrosine (see paper)
37% identity, 96% coverage: 11:287/288 of query aligns to 6:282/365 of 6u60B
Sites not aligning to the query:
5uyyA Crystal structure of prephenate dehydrogenase tyra from bacillus anthracis in complex with l-tyrosine (see paper)
37% identity, 96% coverage: 11:287/288 of query aligns to 14:290/373 of 5uyyA
Sites not aligning to the query:
3b1fA Crystal structure of prephenate dehydrogenase from streptococcus mutans (see paper)
30% identity, 98% coverage: 7:287/288 of query aligns to 7:285/286 of 3b1fA
2f1kA Crystal structure of synechocystis arogenate dehydrogenase (see paper)
29% identity, 97% coverage: 9:288/288 of query aligns to 3:278/279 of 2f1kA
>WP_012470203.1 NCBI__GCF_000020385.1:WP_012470203.1
MSQPVINTFAVIGVGLIGGSFSRALKQAGVVKRVIGFDLDSANLAEALQLGVVDEIAADY
AAAVSSADLVFLAVPVRAMTAAVSACAPFLRPGCVVTDGGSVKDELVVACEQLVPAGCFF
VGGHPIAGTEHSGAKASFATLYQGRRCILTPTSRTDQQALDLVQRLWEAAGSRVECMEPL
THDRVFAAVSHLPHMVAYALVHAVNGSAEEEENILAFSAGGFRDFTRIASSDPSMWRDIA
LMNRLPLLAMLDRYQSEFAALRERVASGDGAWLENYFTTSKRLRDEII
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory