Comparing WP_012470454.1 NCBI__GCF_000020385.1:WP_012470454.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8bj3A Crystal structure of medicago truncatula histidinol-phosphate aminotransferase (hisn6) in complex with histidinol-phosphate (see paper)
32% identity, 93% coverage: 4:363/389 of query aligns to 1:359/360 of 8bj3A
4r5zA Crystal structure of rv3772 encoded aminotransferase (see paper)
37% identity, 66% coverage: 36:293/389 of query aligns to 25:284/353 of 4r5zA
4r2nA Crystal structure of rv3772 in complex with its substrate (see paper)
37% identity, 66% coverage: 36:293/389 of query aligns to 25:284/353 of 4r2nA
Sites not aligning to the query:
4wbtA Crystal structure of histidinol-phosphate aminotransferase from sinorhizobium meliloti in complex with pyridoxal-5'-phosphate
30% identity, 88% coverage: 24:366/389 of query aligns to 22:367/369 of 4wbtA
3ly1D Crystal structure of putative histidinol-phosphate aminotransferase (yp_050345.1) from erwinia carotovora atroseptica scri1043 at 1.80 a resolution
29% identity, 84% coverage: 36:360/389 of query aligns to 19:345/354 of 3ly1D
1fg7A Crystal structure of l-histidinol phosphate aminotransferase with pyridoxal-5'-phosphate (see paper)
30% identity, 86% coverage: 28:360/389 of query aligns to 22:349/354 of 1fg7A
1fg3A Crystal structure of l-histidinol phosphate aminotransferase complexed with l-histidinol (see paper)
30% identity, 86% coverage: 28:360/389 of query aligns to 22:349/354 of 1fg3A
Sites not aligning to the query:
1geyA Crystal structure of histidinol-phosphate aminotransferase complexed with n-(5'-phosphopyridoxyl)-l-glutamate (see paper)
30% identity, 84% coverage: 36:360/389 of query aligns to 16:335/335 of 1geyA
7szpA Crystal structure of histidinol-phosphate aminotransferase from klebsiella pneumoniae subsp. Pneumoniae (strain hs11286)
29% identity, 93% coverage: 1:361/389 of query aligns to 2:350/353 of 7szpA
4r8dA Crystal structure of rv1600 encoded aminotransferase in complex with plp-mes from mycobacterium tuberculosis
30% identity, 87% coverage: 27:363/389 of query aligns to 18:361/369 of 4r8dA
P97084 Threonine-phosphate decarboxylase; L-threonine-O-3-phosphate decarboxylase; EC 4.1.1.81 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
31% identity, 87% coverage: 25:364/389 of query aligns to 14:357/364 of P97084
Sites not aligning to the query:
1lc8A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with its reaction intermediate (see paper)
31% identity, 85% coverage: 33:364/389 of query aligns to 18:351/356 of 1lc8A
Sites not aligning to the query:
1lkcA Crystal structure of l-threonine-o-3-phosphate decarboxylase from salmonella enterica (see paper)
31% identity, 85% coverage: 33:364/389 of query aligns to 17:350/355 of 1lkcA
Sites not aligning to the query:
1lc7A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with a substrate (see paper)
31% identity, 85% coverage: 33:364/389 of query aligns to 21:354/358 of 1lc7A
Sites not aligning to the query:
3cq6A Histidinol-phosphate aminotransferase from corynebacterium glutamicum holo-form (plp covalently bound ) (see paper)
27% identity, 85% coverage: 36:364/389 of query aligns to 28:360/364 of 3cq6A
Sites not aligning to the query:
3cq5B Histidinol-phosphate aminotransferase from corynebacterium glutamicum in complex with pmp (see paper)
27% identity, 85% coverage: 36:364/389 of query aligns to 30:362/366 of 3cq5B
P0DV65 L-serine phosphate decarboxylase; CobD homolog SMUL_1544; SmCobD; L-serine O-phosphate decarboxylase; L-Ser-P decarboxylase; Norcobamide biosynthesis protein SMUL_1544; Threonine phosphate decarboxylase-like enzyme; EC 4.1.1.- from Sulfurospirillum multivorans (strain DM 12446 / JCM 15788 / NBRC 109480) (see paper)
25% identity, 89% coverage: 20:364/389 of query aligns to 27:388/392 of P0DV65
Sites not aligning to the query:
2f8jA Crystal structure of histidinol-phosphate aminotransferase (ec 2.6.1.9) (imidazole acetol-phosphate transferase) (tm1040) from thermotoga maritima at 2.40 a resolution
29% identity, 83% coverage: 41:361/389 of query aligns to 28:333/335 of 2f8jA
1uu0A Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form) (see paper)
29% identity, 80% coverage: 41:352/389 of query aligns to 21:317/328 of 1uu0A
Q9X0D0 Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; EC 2.6.1.9 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
29% identity, 83% coverage: 41:361/389 of query aligns to 27:332/335 of Q9X0D0
>WP_012470454.1 NCBI__GCF_000020385.1:WP_012470454.1
MNLDTLMPQYVRQFETYIPSPPDDELKRMFGIERLIRLNNNENPLGPPPAVAALLRSLDP
ALVPRYPSGDCFHLREKLAAQLGLTPKQLLFGNGANEVIAFVIKAFCEQGDNIVTADRTF
AVYEWIARFSGLEARLAPLNDFGFDEEALLAQVDRRTKLVFICNPNNPTGSWWSRDRLIS
FLERLGPDHLVVLDEAYCEFMDQPDYPDGISLLSRFSNLIIFRTFSKMYGLAGLRIGYLA
GVEQVVDSIRKTCIVYSVNSIAQVAALAAFGDQEFIRATRSMVREGQQMLAELCSTLQLP
LLAGDCNFAMIRLPFSDTLAYRSLMQQGVMIRTMTAFRFPGWIRVSISTRDEMRLFCEAL
SRLVHSRTDRNPLARAYGVSGSMPHISAV
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory