Comparing WP_012506113.1 NCBI__GCF_000020625.1:WP_012506113.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P36204 Bifunctional PGK/TIM; EC 2.7.2.3; EC 5.3.1.1 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
53% identity, 98% coverage: 2:247/252 of query aligns to 402:647/654 of P36204
Sites not aligning to the query:
4y96A Crystal structure of triosephosphate isomerase from gemmata obscuriglobus (see paper)
50% identity, 98% coverage: 2:249/252 of query aligns to 2:249/250 of 4y96A
P27876 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Bacillus subtilis (strain 168) (see paper)
47% identity, 98% coverage: 1:247/252 of query aligns to 1:248/253 of P27876
P00943 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see 2 papers)
46% identity, 98% coverage: 1:248/252 of query aligns to 1:249/253 of P00943
3uwuA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with glycerol-3-phosphate (see paper)
45% identity, 99% coverage: 1:250/252 of query aligns to 1:253/253 of 3uwuA
Q6GIL6 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Staphylococcus aureus (strain MRSA252) (see paper)
45% identity, 99% coverage: 1:250/252 of query aligns to 1:253/253 of Q6GIL6
6neeB Crystal structure of a reconstructed ancestor of triosephosphate isomerase from eukaryotes (see paper)
47% identity, 99% coverage: 2:250/252 of query aligns to 4:252/252 of 6neeB
3uwzA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with glycerol-2-phosphate (see paper)
45% identity, 99% coverage: 1:250/252 of query aligns to 2:254/254 of 3uwzA
3uwwA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with 3-phosphoglyceric acid (see paper)
45% identity, 99% coverage: 1:250/252 of query aligns to 2:254/254 of 3uwwA
3uwvA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with 2-phosphoglyceric acid (see paper)
45% identity, 99% coverage: 1:250/252 of query aligns to 3:255/255 of 3uwvA
1btmA Triosephosphate isomerase (tim) complexed with 2-phosphoglycolic acid (see paper)
46% identity, 98% coverage: 2:248/252 of query aligns to 1:248/251 of 1btmA
6bveA Triosephosphate isomerase of synechocystis in complex with 2- phosphoglycolic acid (see paper)
47% identity, 98% coverage: 1:247/252 of query aligns to 1:239/242 of 6bveA
3uwzB Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with glycerol-2-phosphate (see paper)
44% identity, 99% coverage: 1:250/252 of query aligns to 1:250/250 of 3uwzB
4owgA Crystal structure of rabbit muscle triosephosphate isomerase-pep complex
46% identity, 99% coverage: 2:250/252 of query aligns to 2:246/246 of 4owgA
P00939 Triosephosphate isomerase; TIM; Methylglyoxal synthase; Triose-phosphate isomerase; EC 5.3.1.1; EC 4.2.3.3 from Oryctolagus cuniculus (Rabbit) (see 2 papers)
46% identity, 99% coverage: 2:250/252 of query aligns to 5:249/249 of P00939
1r2rB Crystal structure of rabbit muscle triosephosphate isomerase (see paper)
46% identity, 99% coverage: 2:250/252 of query aligns to 3:247/247 of 1r2rB
4mvaA 1.43 angstrom resolution crystal structure of triosephosphate isomerase (tpia) from escherichia coli in complex with acetyl phosphate. (see paper)
48% identity, 99% coverage: 1:250/252 of query aligns to 1:250/255 of 4mvaA
B1XB85 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Escherichia coli (strain K12 / DH10B) (see paper)
48% identity, 99% coverage: 1:250/252 of query aligns to 1:250/255 of B1XB85
4pocB Structure of triosephosphate isomerase wild type human enzyme. (see paper)
46% identity, 99% coverage: 2:250/252 of query aligns to 3:247/247 of 4pocB
1htiB Crystal structure of recombinant human triosephosphate isomerase at 2.8 angstroms resolution. Triosephosphate isomerase related human genetic disorders and comparison with the trypanosomal enzyme (see paper)
46% identity, 99% coverage: 2:250/252 of query aligns to 4:248/248 of 1htiB
>WP_012506113.1 NCBI__GCF_000020625.1:WP_012506113.1
MRKKIVVGNWKMNKTIAEAVELSSAIIDQLGEVSASCEVGIAPAFPALSGVHGVISGTGI
HLAAQNCHYEDDGAFTGEVSVRMLDEAGCSYVIVGHSERRQYFGDTNPVVNLKVKKALSA
GLNVILCVGETLDEREKGITTEVVTCQVKEGLEGVADIGDIVIAYEPVWAIGTGKTASSL
QAQEVHASIRATVAGLYSEPAAAGVRIQYGGSVKPSNAEELFAMPDIDGGLIGGASLNAE
DFVAIVKAAEKS
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Lawrence Berkeley National Laboratory