Comparing WP_012536069.1 NCBI__GCF_000021485.1:WP_012536069.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
Q6FEQ3 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
64% identity, 97% coverage: 3:375/383 of query aligns to 1:373/387 of Q6FEQ3
P45131 Homoserine O-acetyltransferase; HAT; Homoserine O-trans-acetylase; Homoserine transacetylase; HTA; EC 2.3.1.31 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
44% identity, 90% coverage: 21:366/383 of query aligns to 11:347/358 of P45131
Sites not aligning to the query:
D2Z028 L-serine/homoserine O-acetyltransferase; Homoserine O-trans-acetylase; EC 2.3.1.30; EC 2.3.1.31 from Streptomyces lavendulae (see paper)
40% identity, 91% coverage: 29:378/383 of query aligns to 23:374/374 of D2Z028
5w8oB Homoserine transacetylase metx from mycobacterium hassiacum (see paper)
37% identity, 88% coverage: 24:361/383 of query aligns to 9:329/346 of 5w8oB
8f2lA Crystal structure of mycobacterium tuberculosis homoserine transacetylase in complex with l-homoserine (see paper)
33% identity, 93% coverage: 24:380/383 of query aligns to 18:367/367 of 8f2lA
7rytB Crystal structure of mycobacterium tuberculosis acetylated homoserine transacetylase with coenzyme a (see paper)
33% identity, 93% coverage: 24:380/383 of query aligns to 18:367/368 of 7rytB
6puxA Homoserine transacetylase metx from mycobacterium tuberculosis (see paper)
33% identity, 92% coverage: 24:375/383 of query aligns to 19:363/366 of 6puxA
Q10341 Serine O-succinyltransferase; SST; EC 2.3.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
39% identity, 75% coverage: 21:306/383 of query aligns to 87:368/504 of Q10341
Sites not aligning to the query:
6iohA Crystal structure of homoserine o-acetyltransferase in complex with homoserine from mycobacterium smegmatis atcc 19420 (see paper)
32% identity, 94% coverage: 3:361/383 of query aligns to 3:349/375 of 6iohA
6ioiA Crystal structure of homoserine o-acetyltransferase in complex with coa from mycobacterium smegmatis atcc 19420 (see paper)
32% identity, 94% coverage: 3:361/383 of query aligns to 3:349/366 of 6ioiA
2vavB Crystal structure of deacetylcephalosporin c acetyltransferase (dac- soak) (see paper)
34% identity, 90% coverage: 16:361/383 of query aligns to 11:334/350 of 2vavB
2vatA Crystal structure of deacetylcephalosporin c acetyltransferase in complex with coenzyme a (see paper)
34% identity, 90% coverage: 16:361/383 of query aligns to 10:332/347 of 2vatA
>WP_012536069.1 NCBI__GCF_000021485.1:WP_012536069.1
MPVEIPADSVGLVTPQTVTFSAPLELECGRSLPGYTLTYETYGTLNAQRSNAILLCHALS
GDHHAAGYHSMDDRKPGWWEHLLGPGKAMDTERFFFVCANFIGSCKGSTGPASTNPETGA
PWGLDFPMVTVRDWVKTQAELADYLGIEQWAAVVGGSLGGMQVMQWSMDYPERLRHAVVI
AAAPKLTAQNIAFNEVCRQAIMTDPEFYNGRYYAHNTKPRRGLSLARMIGHITYLSDNAM
RTKFGRDTRGGKAFSFGFDVDFEVESYLRYQGSSFVERFDANSYLYITKALDYFDPASTW
GGNLAEAFASTRANFLVISFSSDWRFSPERSREIVQALYTCNRDVSYAEIEAEHGHDSFL
MPIPQYVAVLSTYLGRVAEEIGA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory