Comparing WP_012565800.1 NCBI__GCF_000016185.1:WP_012565800.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5e25A Crystal structure of branched-chain aminotransferase from thermophilic archaea geoglobus acetivorans complexed with alpha-ketoglutarate (see paper)
33% identity, 86% coverage: 4:236/271 of query aligns to 4:245/290 of 5e25A
Sites not aligning to the query:
5mr0D Thermophilic archaeal branched-chain amino acid transaminases from geoglobus acetivorans and archaeoglobus fulgidus: biochemical and structural characterisation (see paper)
33% identity, 86% coverage: 5:236/271 of query aligns to 4:244/290 of 5mr0D
Sites not aligning to the query:
7p3tB Transaminase of gamma-proteobacterium (see paper)
33% identity, 90% coverage: 3:246/271 of query aligns to 4:260/299 of 7p3tB
2y4rA Crystal structure of 4-amino-4-deoxychorismate lyase from pseudomonas aeruginosa (see paper)
38% identity, 86% coverage: 6:238/271 of query aligns to 3:236/270 of 2y4rA
8pnyA Crystal structure of d-amino acid aminotransferase from blastococcus saxobsidens complexed with phenylhydrazine and in its apo form (see paper)
36% identity, 89% coverage: 5:245/271 of query aligns to 6:254/278 of 8pnyA
8pnxA Crystal structure of d-amino acid aminotransferase from blastococcus saxobsidens in pmp form
36% identity, 89% coverage: 5:245/271 of query aligns to 6:254/278 of 8pnxA
8pnwA Crystal structure of d-amino acid aminotransferase from blastococcus saxobsidens in holo form with plp (see paper)
36% identity, 89% coverage: 5:245/271 of query aligns to 6:254/278 of 8pnwA
2ej3A Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase complexed with gabapentin
31% identity, 69% coverage: 4:190/271 of query aligns to 6:195/297 of 2ej3A
Sites not aligning to the query:
2eiyA Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase complexed with 4-methylvaleric acid
31% identity, 69% coverage: 4:190/271 of query aligns to 6:195/297 of 2eiyA
Sites not aligning to the query:
1wrvA Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase
31% identity, 69% coverage: 4:190/271 of query aligns to 6:195/297 of 1wrvA
Sites not aligning to the query:
2ej2A Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase complexed with n-(5'-phosphopyridoxyl)-l-glutamate
31% identity, 69% coverage: 4:190/271 of query aligns to 6:192/294 of 2ej2A
Sites not aligning to the query:
6thqB Crystal structure of branched-chain aminotransferase from thermophilic archaea thermoproteus uzoniensis with norvaline
32% identity, 84% coverage: 5:231/271 of query aligns to 9:247/301 of 6thqB
Sites not aligning to the query:
2ej0B Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase with pyridoxamine 5'-phosphate
30% identity, 69% coverage: 4:190/271 of query aligns to 6:203/305 of 2ej0B
Sites not aligning to the query:
3wwhA Crystal structure of the first r-stereoselective -transaminase identified from arthrobacter sp. Knk168 (ferm-bp-5228) (see paper)
30% identity, 87% coverage: 6:241/271 of query aligns to 39:286/329 of 3wwhA
4whxA X-ray crystal structure of an amino acid aminotransferase from burkholderia pseudomallei bound to the co-factor pyridoxal phosphate
29% identity, 86% coverage: 5:236/271 of query aligns to 9:255/306 of 4whxA
Sites not aligning to the query:
1iyeA Crystal structure of eschelichia coli branched-chain amino acid aminotransferase (see paper)
26% identity, 86% coverage: 5:236/271 of query aligns to 5:252/304 of 1iyeA
Sites not aligning to the query:
1iydA Crystal structure of eschelichia coli branched-chain amino acid aminotransferase (see paper)
26% identity, 86% coverage: 5:236/271 of query aligns to 5:252/304 of 1iydA
Sites not aligning to the query:
1i1mA Crystal structure of escherichia coli branched-chain amino acid aminotransferase. (see paper)
26% identity, 86% coverage: 5:236/271 of query aligns to 5:252/304 of 1i1mA
Sites not aligning to the query:
1i1lA Crystal structure of eschelichia coli branched-chain amino acid aminotransferase. (see paper)
26% identity, 86% coverage: 5:236/271 of query aligns to 5:252/304 of 1i1lA
Sites not aligning to the query:
1i2lA Deoxychorismate lyase from escherichia coli with inhibitor
30% identity, 80% coverage: 23:239/271 of query aligns to 16:238/269 of 1i2lA
>WP_012565800.1 NCBI__GCF_000016185.1:WP_012565800.1
MTPILWLDGTLRPAGEGRVDPGDRGLLLGDGLFETICVRGGRALRLEAHFARLRTGAGIL
GLPVPAGDDALADALEQVVRANGLADAVVRLTLTAGPGPRGLPRPAPPRPTLLLTAGPLP
LPPPPARLLVARSTRRNEHSPLSRVKSLNYLDSILARREAAAAGADDAVLLNTAGRVAEA
SAANLFLRLDCGWVTPPVSEGALPGTMRAVLAEAWDAAERPVTVADLHRADAIVLTTALG
VREVAGMLEPAALPEAAPPGTSPLSSNGSPR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory