SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_012568523.1 NCBI__GCF_000016185.1:WP_012568523.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

1nsjA Crystal structure of phosphoribosyl anthranilate isomerase from thermotoga maritima (see paper)
30% identity, 88% coverage: 6:198/219 of query aligns to 3:183/205 of 1nsjA

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1nsjA
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V

1lbmA Crystal structure of phosphoribosyl anthranilate isomerase (prai) in complex with reduced 1-(o-carboxyphenylamino)-1-deoxyribulose 5- phosphate (rcdrp) (see paper)
28% identity, 88% coverage: 6:198/219 of query aligns to 3:172/194 of 1lbmA

query
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1lbmA
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V

Query Sequence

>WP_012568523.1 NCBI__GCF_000016185.1:WP_012568523.1
MARRTRLKVCCIASVEEARIAVAAGADALGLVAAMPSGPGPIPDEAIAEIAATVPPPVAT
FLLTCRTDPDGVVEHVRRCGTNTVQLVDAVAPETYAALRRHCPAVRIVQVLHVEDEAALE
EARRVAPQVDALLLDSGRPSLAVKELGGTGRVHDWAVSARIVAGSPVPVFLAGGLKAANV
ADAVRAVRPFGIDLCSGVRTDGRLDPARLEALVAALGAV

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory