Comparing WP_012569198.1 NCBI__GCF_000016185.1:WP_012569198.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
4wjiA Crystal structure of cyclohexadienyl dehydrogenase from sinorhizobium meliloti in complex with NADP and tyrosine
63% identity, 98% coverage: 7:295/296 of query aligns to 4:291/293 of 4wjiA
3ggpA Crystal structure of prephenate dehydrogenase from a. Aeolicus in complex with hydroxyphenyl propionate and NAD+ (see paper)
36% identity, 96% coverage: 9:292/296 of query aligns to 7:286/286 of 3ggpA
3gggD The crystal structure of a. Aeolicus prephenate dehydrogenase in complex with tyrosine and NAD+ (see paper)
36% identity, 92% coverage: 9:279/296 of query aligns to 15:283/293 of 3gggD
3ggoA Crystal structure of prephenate dehydrogenase from a. Aeolicus with hpp and nadh (see paper)
36% identity, 92% coverage: 9:279/296 of query aligns to 7:275/285 of 3ggoA
5uyyA Crystal structure of prephenate dehydrogenase tyra from bacillus anthracis in complex with l-tyrosine (see paper)
31% identity, 95% coverage: 8:287/296 of query aligns to 10:287/373 of 5uyyA
Sites not aligning to the query:
6u60B Crystal structure of prephenate dehydrogenase tyra from bacillus anthracis in complex with NAD and l-tyrosine (see paper)
31% identity, 95% coverage: 8:287/296 of query aligns to 2:279/365 of 6u60B
Sites not aligning to the query:
3b1fA Crystal structure of prephenate dehydrogenase from streptococcus mutans (see paper)
34% identity, 95% coverage: 10:290/296 of query aligns to 9:285/286 of 3b1fA
2f1kA Crystal structure of synechocystis arogenate dehydrogenase (see paper)
31% identity, 96% coverage: 9:292/296 of query aligns to 2:279/279 of 2f1kA
>WP_012569198.1 NCBI__GCF_000016185.1:WP_012569198.1
MTAPPLFPRVAVIGLGLIGSSLARVLRADPTLAGELVAADRSAAVCARVLELGLADRAET
DPACAVAGADLVILAVPIGACADLAAAIGPHLKPGAILTDVGSVKQAVIRDVAPQVPDGV
HFVPGHPIAGTEHSGPDAGFADLFRGRWCILTPPPGTDPAAVEKVVELWRRAGSMIEVME
PGHHDRVLAITSHLPHLIAYTIVGTATDLEEHLKSEVIRFSASGFRDFTRIAASDPVMWR
DIFLNNREAVLEIIQRFTEDLTALQRAIRWGEAETLEHLFTRTRDIRRGIIDARQA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory