Comparing WP_012590062.1 NCBI__GCF_000021745.1:WP_012590062.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
Q6FEQ3 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
47% identity, 93% coverage: 25:390/394 of query aligns to 16:382/387 of Q6FEQ3
P45131 Homoserine O-acetyltransferase; HAT; Homoserine O-trans-acetylase; Homoserine transacetylase; HTA; EC 2.3.1.31 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
44% identity, 86% coverage: 36:372/394 of query aligns to 19:347/358 of P45131
Sites not aligning to the query:
D2Z028 L-serine/homoserine O-acetyltransferase; Homoserine O-trans-acetylase; EC 2.3.1.30; EC 2.3.1.31 from Streptomyces lavendulae (see paper)
41% identity, 94% coverage: 12:380/394 of query aligns to 1:370/374 of D2Z028
5w8oB Homoserine transacetylase metx from mycobacterium hassiacum (see paper)
38% identity, 86% coverage: 30:368/394 of query aligns to 8:330/346 of 5w8oB
6puxA Homoserine transacetylase metx from mycobacterium tuberculosis (see paper)
37% identity, 89% coverage: 30:381/394 of query aligns to 18:366/366 of 6puxA
8f2lA Crystal structure of mycobacterium tuberculosis homoserine transacetylase in complex with l-homoserine (see paper)
37% identity, 89% coverage: 30:381/394 of query aligns to 17:365/367 of 8f2lA
7rytB Crystal structure of mycobacterium tuberculosis acetylated homoserine transacetylase with coenzyme a (see paper)
37% identity, 89% coverage: 30:381/394 of query aligns to 17:365/368 of 7rytB
Q10341 Serine O-succinyltransferase; SST; EC 2.3.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
42% identity, 71% coverage: 34:312/394 of query aligns to 93:368/504 of Q10341
Sites not aligning to the query:
6ioiA Crystal structure of homoserine o-acetyltransferase in complex with coa from mycobacterium smegmatis atcc 19420 (see paper)
37% identity, 88% coverage: 22:368/394 of query aligns to 13:350/366 of 6ioiA
6iohA Crystal structure of homoserine o-acetyltransferase in complex with homoserine from mycobacterium smegmatis atcc 19420 (see paper)
37% identity, 88% coverage: 22:368/394 of query aligns to 13:350/375 of 6iohA
2vavB Crystal structure of deacetylcephalosporin c acetyltransferase (dac- soak) (see paper)
34% identity, 90% coverage: 31:383/394 of query aligns to 19:350/350 of 2vavB
2vatA Crystal structure of deacetylcephalosporin c acetyltransferase in complex with coenzyme a (see paper)
34% identity, 89% coverage: 31:381/394 of query aligns to 18:346/347 of 2vatA
>WP_012590062.1 NCBI__GCF_000021745.1:WP_012590062.1
MTIVLTHKLSGLREVDAPHSLVAHFGPDHALQMDSGGRLNQWTIAYQTYGELNAAKSNAI
LVCHALTGDQHVANAHPVTGKPGWWSTMVGPGRPIDTDRYFVICSNVIGGCMGTTGPASL
NPQTGRPYGLELPIVTIRDMVRAQAMLIDHLGVDTLFCVVGGSMGGMQVLQWVASFPERV
FSAMPIATAAKHSSQNIAFHEVGRQAVMADPDWRKGRYLEEGVIPTKGLAVARMAAHITY
LSDEALQSKFGRKLQDRDAPTFSFDAEFQIENYLRYQGSSFVDRFDPNSYLYVTRACDYF
DLAADYDGSLARAFQGVKARFCVVSFNSDWLYPTAASRAIVHALNAGGASVSFVDIETDR
GHDAFLLDLPEFIATSQGFLDSAAKARGLPPAAP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory