Comparing WP_012708601.1 NCBI__GCF_000018545.1:WP_012708601.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 16 hits to proteins with known functional sites (download)
8f9xA Cyclase-phosphotriesterase from ruegeria pomeroyi dss-3
67% identity, 84% coverage: 45:273/273 of query aligns to 2:230/230 of 8f9xA
5nnbA Isatin hydrolase a (iha) from labrenzia aggregata with isatinate bound (see paper)
36% identity, 85% coverage: 41:273/273 of query aligns to 8:254/255 of 5nnbA
5nnaD Isatin hydrolase a (iha) from labrenzia aggregata bound to benzyl benzoate (see paper)
36% identity, 85% coverage: 41:273/273 of query aligns to 16:262/264 of 5nnaD
5nmpA Isatin hydrolase a (iha) from ralstonia solanacearum (see paper)
34% identity, 85% coverage: 41:273/273 of query aligns to 16:264/265 of 5nmpA
4m8dD Crystal structure of an isatin hydrolase bound to product analogue thioisatinate (see paper)
34% identity, 90% coverage: 28:273/273 of query aligns to 2:260/263 of 4m8dD
A0NLY7 Isatin hydrolase; Isatin amidohydrolase; Isatin hydrolase isoform b; IH-b; EC 3.5.2.20 from Roseibium aggregatum (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 / IAM 12614 / B1) (Stappia aggregata) (see paper)
34% identity, 90% coverage: 28:273/273 of query aligns to 2:260/263 of A0NLY7
4m8dB Crystal structure of an isatin hydrolase bound to product analogue thioisatinate (see paper)
34% identity, 90% coverage: 28:273/273 of query aligns to 1:259/262 of 4m8dB
8hmoA Crystal structure of metal-dependent hydrolase complexed with manganese from bacillus smithii
27% identity, 82% coverage: 50:272/273 of query aligns to 3:201/205 of 8hmoA
4cobA Crystal structure kynurenine formamidase from pseudomonas aeruginosa (see paper)
33% identity, 27% coverage: 52:126/273 of query aligns to 4:79/206 of 4cobA
Sites not aligning to the query:
Q9I234 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
33% identity, 27% coverage: 52:126/273 of query aligns to 8:83/213 of Q9I234
Sites not aligning to the query:
4cz1A Crystal structure of kynurenine formamidase from bacillus anthracis complexed with 2-aminoacetophenone. (see paper)
33% identity, 30% coverage: 52:133/273 of query aligns to 6:88/207 of 4cz1A
Sites not aligning to the query:
4co9A Crystal structure of kynurenine formamidase from bacillus anthracis (see paper)
33% identity, 30% coverage: 52:133/273 of query aligns to 6:88/207 of 4co9A
Sites not aligning to the query:
Q81PP9 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Bacillus anthracis (see paper)
33% identity, 30% coverage: 52:133/273 of query aligns to 8:90/209 of Q81PP9
Sites not aligning to the query:
1r61A The structure of predicted metal-dependent hydrolase from bacillus stearothermophilus
25% identity, 81% coverage: 50:270/273 of query aligns to 5:201/205 of 1r61A
B4E9I9 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) (see paper)
29% identity, 27% coverage: 52:126/273 of query aligns to 6:81/213 of B4E9I9
Sites not aligning to the query:
4cogA Crystal structure of kynurenine formamidase from burkholderia cenocepacia (see paper)
29% identity, 27% coverage: 52:126/273 of query aligns to 4:79/207 of 4cogA
Sites not aligning to the query:
>WP_012708601.1 NCBI__GCF_000018545.1:WP_012708601.1
MCDACVIESVKQQMLSRRSFFRAAAVGTAGVAAAGMGIAPAALAAGHAGVTDLTHELHEE
FPTFFGQQQFFREQKFNFAEHTFNLFELRVNEHTGTHVDAPLHFSADGLSVAELPVEKLV
VPLCVVDIRERASADPDAQVTPDDIKAWIAANGDIPENACVAMLSGWAEHIGTDKFRNAD
SAGKLHFPGFHVEAAKYLLEETKTAGIAVDTLSLDHGISPDFATHRAWLPEGRWGLEAAA
NLDKLPAKGATLVLGAPKHRGGTGGPARVFALV
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory