Comparing WP_012709582.1 NCBI__GCF_000018545.1:WP_012709582.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 7 hits to proteins with known functional sites (download)
2r46A Crystal structure of escherichia coli glycerol-3-phosphate dehydrogenase in complex with 2-phosphopyruvic acid. (see paper)
51% identity, 92% coverage: 31:497/505 of query aligns to 28:489/495 of 2r46A
Sites not aligning to the query:
2r45A Crystal structure of escherichia coli glycerol-3-phosphate dehydrogenase in complex with 2-phospho-d-glyceric acid (see paper)
51% identity, 92% coverage: 31:497/505 of query aligns to 28:489/495 of 2r45A
Sites not aligning to the query:
2qcuB Crystal structure of glycerol-3-phosphate dehydrogenase from escherichia coli (see paper)
51% identity, 92% coverage: 31:497/505 of query aligns to 28:489/501 of 2qcuB
Sites not aligning to the query:
2rgoB Structure of alpha-glycerophosphate oxidase from streptococcus sp.: A template for the mitochondrial alpha-glycerophosphate dehydrogenase (see paper)
31% identity, 81% coverage: 29:437/505 of query aligns to 39:465/530 of 2rgoB
Sites not aligning to the query:
2rgoA Structure of alpha-glycerophosphate oxidase from streptococcus sp.: A template for the mitochondrial alpha-glycerophosphate dehydrogenase (see paper)
29% identity, 90% coverage: 29:481/505 of query aligns to 41:514/557 of 2rgoA
Sites not aligning to the query:
Q9SS48 Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial; Protein SUGAR-DEPENDENT 6; EC 1.1.5.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
30% identity, 94% coverage: 7:483/505 of query aligns to 74:573/629 of Q9SS48
3da1A X-ray structure of the glycerol-3-phosphate dehydrogenase from bacillus halodurans complexed with fad. Northeast structural genomics consortium target bhr167.
31% identity, 95% coverage: 1:479/505 of query aligns to 14:442/496 of 3da1A
>WP_012709582.1 NCBI__GCF_000018545.1:WP_012709582.1
MSEQAIFDVFVIGGGINGCGIARDAVGRGYSVALAEMDDFASGTSSGSTKLIHGGLRYLE
HYEFRLVREALMEREVLWAMAPHVIWPMRFVLPYHKGGPRPAWLIRLGLFLYDHIGGRKL
LPATSTLDMTRDAAGGPLKRLFTKAFEYSDGWVDDARLVVLNARDAADRGARIMARTRVV
SARRENGRWAIETEDAQTGARETLRARLLVNATGPWVDRVLADTLGKNDVHNVRLVQGSH
IVVKRKFDDPRAYFFQNPDGRIMFAIPYQNDFTLIGTTDRDFTGNPADVRISDAEIDYLC
KSASEYFSDPVTTDDIVWTYSAVRPLYDDGASKAQEATRDYVLRVEGQNGQAPLLNVFGG
KLTTYRRLAESALEKIGEAIGTKGSKWTATSHLPGGDFAATAYDTEVDMLKARYPFLALS
HARRLVRLYGTQAASLLGHAASQADLGKHFGTDLYEVEVDWLIGQEWARRAEDVLWRRTK
LGLKLTPAEIAELEDYMRGAVNAAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory