Comparing WP_012757420.1 NCBI__GCF_000023185.1:WP_012757420.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see paper)
41% identity, 96% coverage: 5:489/507 of query aligns to 1:483/501 of P04983
P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
33% identity, 42% coverage: 12:223/507 of query aligns to 5:220/343 of P30750
Sites not aligning to the query:
6cvlD Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
32% identity, 43% coverage: 7:223/507 of query aligns to 1:221/344 of 6cvlD
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form (see paper)
32% identity, 43% coverage: 7:223/507 of query aligns to 1:221/344 of 3tuzC
Sites not aligning to the query:
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form (see paper)
32% identity, 43% coverage: 7:223/507 of query aligns to 1:221/344 of 3tuiC
P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 3 papers)
31% identity, 48% coverage: 12:255/507 of query aligns to 21:261/378 of P69874
Sites not aligning to the query:
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
28% identity, 43% coverage: 8:223/507 of query aligns to 2:215/241 of 4u00A
8y5iA Cryo-em structure of e.Coli spermidine transporter potd-potabc in translocation intermidiate state (see paper)
30% identity, 48% coverage: 12:255/507 of query aligns to 6:246/358 of 8y5iA
3c4jA Abc protein artp in complex with atp-gamma-s
28% identity, 43% coverage: 14:231/507 of query aligns to 9:225/242 of 3c4jA
3c41J Abc protein artp in complex with amp-pnp/mg2+
28% identity, 43% coverage: 14:231/507 of query aligns to 9:225/242 of 3c41J
2olkA Abc protein artp in complex with adp-beta-s
28% identity, 43% coverage: 14:231/507 of query aligns to 9:225/242 of 2olkA
2oljA Abc protein artp in complex with adp/mg2+
28% identity, 43% coverage: 14:231/507 of query aligns to 9:225/242 of 2oljA
4ymuJ Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
28% identity, 43% coverage: 8:223/507 of query aligns to 1:215/240 of 4ymuJ
3d31A Modbc from methanosarcina acetivorans (see paper)
31% identity, 44% coverage: 23:244/507 of query aligns to 15:231/348 of 3d31A
Sites not aligning to the query:
8k1oB Mycobacterial efflux pump, amppnp bound state (see paper)
31% identity, 42% coverage: 13:223/507 of query aligns to 10:210/215 of 8k1oB
8k1pB Mycobacterial efflux pump, adp+vanadate bound state
31% identity, 42% coverage: 13:223/507 of query aligns to 8:208/213 of 8k1pB
5x40A Structure of a cbio dimer bound with amppcp (see paper)
32% identity, 43% coverage: 8:223/507 of query aligns to 4:219/280 of 5x40A
4yerA Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
26% identity, 50% coverage: 5:260/507 of query aligns to 1:247/285 of 4yerA
6mjpA Lptb(e163q)fgc from vibrio cholerae (see paper)
28% identity, 47% coverage: 265:502/507 of query aligns to 7:237/240 of 6mjpA
8wm7D Cryo-em structure of cyanobacterial nitrate/nitrite transporter nrtbcd in complex with signalling protein pii (see paper)
29% identity, 45% coverage: 6:232/507 of query aligns to 2:226/257 of 8wm7D
>WP_012757420.1 NCBI__GCF_000023185.1:WP_012757420.1
MIHDFENVLAASGISKFFPGAVALDKVDFTLRRGEVHALLGENGAGKSTLIKCITGAYHR
DEGSLMLEGQEINPANTLAAQKLGIGTVYQEVNLLSNLSVAENLFLGRQPRRFGMTDVRS
MNRKARDLLAGYGVDIDVTAELGRFSVAVQQVVAIARAVDLSGKVLILDEPTASLDNQEV
ALLFRIIEDLKKRGLGIVFITHFLEQVYAISDRITVLRNGKLVGTRDAADLPRQGLIAMM
LGRELAHVEETVRERSLAAGDVRYHFAGYGKRGKVKPFDLEVRAGEVVGVAGLLGSGRTE
TAELLFGIEHADSGSATIDGQPVTISSPRAAIAKGFGFCPEDRKTDGIIGDLSIRENIAL
ALQARRGWTRPLSRAEQNTLADRYIKALDIRTTDREKPIRLLSGGNQQKAILARWLATNP
KFLILDEPTRGIDVGAHAEIIRLIEELCAGGMSLIVISSELEELVAYSSRVIVLRDRQHI
AELTGERITAAGIVEAIAAAEHKMEDA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory