Comparing WP_012758951.1 NCBI__GCF_000023185.1:WP_012758951.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 14 hits to proteins with known functional sites (download)
1v72A Crystal structure of phenylserine aldolase from pseudomonas putida
46% identity, 98% coverage: 3:346/350 of query aligns to 7:339/345 of 1v72A
O50584 Low specificity L-threonine aldolase; Low specificity L-TA; EC 4.1.2.48 from Pseudomonas sp. (strain NCIMB 10558) (see paper)
42% identity, 88% coverage: 3:309/350 of query aligns to 8:312/346 of O50584
5vyeB Crystal structure of l-threonine aldolase from pseudomonas putida
41% identity, 88% coverage: 3:309/350 of query aligns to 6:310/344 of 5vyeB
1lw5B X-ray structure of l-threonine aldolase (low-specificity) in complex with glycine (see paper)
28% identity, 55% coverage: 30:223/350 of query aligns to 30:221/343 of 1lw5B
Sites not aligning to the query:
1lw4B X-ray structure of l-threonine aldolase (low-specificity) in complex with l-allo-threonine (see paper)
28% identity, 55% coverage: 30:223/350 of query aligns to 30:221/343 of 1lw4B
Sites not aligning to the query:
1jg8D Crystal structure of threonine aldolase (low-specificity)
28% identity, 55% coverage: 30:223/350 of query aligns to 31:222/344 of 1jg8D
Sites not aligning to the query:
4rjyA Crystal structure of e. Coli l-threonine aldolase in complex with a non-covalently uncleaved bound l-serine substrate (see paper)
33% identity, 42% coverage: 44:190/350 of query aligns to 44:185/332 of 4rjyA
Sites not aligning to the query:
4lnmA Structure of escherichia coli threonine aldolase in complex with serine (see paper)
33% identity, 42% coverage: 44:190/350 of query aligns to 44:185/331 of 4lnmA
Sites not aligning to the query:
4lnlA Structure of escherichia coli threonine aldolase in complex with allo- thr (see paper)
33% identity, 42% coverage: 44:190/350 of query aligns to 44:185/332 of 4lnlA
Sites not aligning to the query:
4lnjA Structure of escherichia coli threonine aldolase in unliganded form (see paper)
33% identity, 42% coverage: 44:190/350 of query aligns to 44:185/332 of 4lnjA
Sites not aligning to the query:
3wgbD Crystal structure of aeromonas jandaei l-allo-threonine aldolase (see paper)
31% identity, 43% coverage: 39:190/350 of query aligns to 39:183/324 of 3wgbD
Sites not aligning to the query:
3wlxA Crystal structure of low-specificity l-threonine aldolase from escherichia coli
32% identity, 42% coverage: 44:190/350 of query aligns to 44:185/331 of 3wlxA
Sites not aligning to the query:
O07051 L-allo-threonine aldolase; L-allo-TA; L-allo-threonine acetaldehyde-lyase; EC 4.1.2.49 from Aeromonas jandaei (see paper)
31% identity, 43% coverage: 39:190/350 of query aligns to 41:187/338 of O07051
Sites not aligning to the query:
3wgcB Aeromonas jandaei l-allo-threonine aldolase h128y/s292r double mutant (see paper)
30% identity, 43% coverage: 39:190/350 of query aligns to 40:186/333 of 3wgcB
Sites not aligning to the query:
>WP_012758951.1 NCBI__GCF_000023185.1:WP_012758951.1
MFFASDNWAGAHKSIAERLLTESTGFAAAYGAGDLDRKVEARFSEIFEREVSVFFVATGT
AANSLSLASVQRPGGITFCHSEAHVIEDECGAPEFFSGAARLVAIDGEAGKIDPAKLSAK
IASFPEDAVHHGRASAVTITQATEIGTVYSLPEIGEIAAISRKRNLPLHMDGARFANALV
ALGATPAEMTWKRGVDMLSFGGTKNGCWCAEAIVFFNPDRAREMPFIRKRAAQLFSKSRF
IAAQFDAYFEDGLWLDLARHSNGMADRLRAGIGTSNSARLAWPTASNEVFAVVSKSAVKI
AEEKGAKFYEWPVPAATPELVSESETLIRLVTSFATTEADVDGFLKCLAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory