Comparing WP_012759184.1 NCBI__GCF_000023185.1:WP_012759184.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 11 hits to proteins with known functional sites (download)
4wjiA Crystal structure of cyclohexadienyl dehydrogenase from sinorhizobium meliloti in complex with NADP and tyrosine
82% identity, 94% coverage: 4:293/307 of query aligns to 3:292/293 of 4wjiA
3ggpA Crystal structure of prephenate dehydrogenase from a. Aeolicus in complex with hydroxyphenyl propionate and NAD+ (see paper)
35% identity, 93% coverage: 2:287/307 of query aligns to 2:285/286 of 3ggpA
3ggoA Crystal structure of prephenate dehydrogenase from a. Aeolicus with hpp and nadh (see paper)
35% identity, 93% coverage: 2:287/307 of query aligns to 2:285/285 of 3ggoA
3gggD The crystal structure of a. Aeolicus prephenate dehydrogenase in complex with tyrosine and NAD+ (see paper)
35% identity, 93% coverage: 2:287/307 of query aligns to 10:293/293 of 3gggD
5uyyA Crystal structure of prephenate dehydrogenase tyra from bacillus anthracis in complex with l-tyrosine (see paper)
30% identity, 92% coverage: 7:287/307 of query aligns to 11:290/373 of 5uyyA
Sites not aligning to the query:
6u60B Crystal structure of prephenate dehydrogenase tyra from bacillus anthracis in complex with NAD and l-tyrosine (see paper)
30% identity, 92% coverage: 7:287/307 of query aligns to 3:282/365 of 6u60B
Sites not aligning to the query:
3b1fA Crystal structure of prephenate dehydrogenase from streptococcus mutans (see paper)
33% identity, 91% coverage: 8:287/307 of query aligns to 9:285/286 of 3b1fA
2f1kA Crystal structure of synechocystis arogenate dehydrogenase (see paper)
30% identity, 92% coverage: 7:289/307 of query aligns to 2:279/279 of 2f1kA
5t57A Crystal structure of a semialdehyde dehydrogenase NAD-binding protein from cupriavidus necator in complex with calcium and NAD
31% identity, 42% coverage: 6:135/307 of query aligns to 3:129/276 of 5t57A
Sites not aligning to the query:
F8GV06 D-apionate oxidoisomerase; EC 1.1.1.421 from Cupriavidus necator (strain ATCC 43291 / DSM 13513 / CCUG 52238 / LMG 8453 / N-1) (Ralstonia eutropha)
31% identity, 42% coverage: 6:135/307 of query aligns to 3:129/276 of F8GV06
Sites not aligning to the query:
5t9fB Prephenate dehydrogenase n222d mutant from soybean (see paper)
24% identity, 76% coverage: 7:238/307 of query aligns to 4:215/253 of 5t9fB
Sites not aligning to the query:
>WP_012759184.1 NCBI__GCF_000023185.1:WP_012759184.1
MSVQFDRIALIGIGLIGSSLAYDIRRLGLAREIVVATRSPDTLKRAEELGLGDRYTTSSQ
DAVKDADLVIVSVPVGASESVAKEISASLKPGAIVTDVGSTKASVIAQMLPHMPDNVHFI
PGHPLAGTEKSGPDAGFPGLFEGRWCIFTPVADTDETALKRLRSFWEALGSKVDEMDAEH
HDKVLAIVSHLPHIIAYNIVGTADDLETVTESEVIKYSASGFRDFTRLAASDPTMWRDVC
LHNRDAILEMLARFSEDLAYLQRAIRWGEGDKIFELFTRTRAIRRSIVQAGQDVDAPDFG
RHALDKK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory