SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_012759370.1 NCBI__GCF_000023185.1:WP_012759370.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 3 hits to proteins with known functional sites (download)

2gtvX Nmr structure of monomeric chorismate mutase from methanococcus jannaschii (see paper)
28% identity, 90% coverage: 8:102/106 of query aligns to 3:101/104 of 2gtvX

query
sites
2gtvX
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T

1ecmB Atomic structure of the buried catalytic pocket of escherichia coli chorismate mutase
30% identity, 84% coverage: 10:98/106 of query aligns to 2:90/95 of 1ecmB

query
sites
1ecmB
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H

P0A9J8 Bifunctional chorismate mutase/prephenate dehydratase; Chorismate mutase-prephenate dehydratase; P-protein; EC 5.4.99.5; EC 4.2.1.51 from Escherichia coli (strain K12)
30% identity, 84% coverage: 10:98/106 of query aligns to 7:95/386 of P0A9J8

query
sites
P0A9J8
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Query Sequence

>WP_012759370.1 NCBI__GCF_000023185.1:WP_012759370.1
MIDPNVKSQLASYRQSIDNIDAALVHMLAERFRCTKEVGVLKAKYNLPPADPAREEYQIE
RLRQLAKAANLDPDFAEKFLNFVIKEVIRHHEQIAADHAEQSAAAR

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory