SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_012854191.1 NCBI__GCF_000024385.1:WP_012854191.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 3 hits to proteins with known functional sites (download)

1ko8A Crystal structure of gluconate kinase (see paper)
38% identity, 91% coverage: 7:170/180 of query aligns to 7:169/172 of 1ko8A

query
sites
1ko8A
Q
 
H
V
 
I
V
 
Y
V
 
V
V
 
L
A
 
M
G
 
G
V
 
V
S
|
S
G
 
G
T
 
S
G
 
G
K
 
K
S
 
S
T
 
A
V
 
V
G
 
A
G
 
S
L
 
E
L
 
V
A
 
A
R
 
H
T
 
Q
L
 
L
G
 
H
W
 
A
E
 
A
F
 
F
A
 
L
D
 
D
A
 
G
D
 
D
D
 
F
L
 
L
H
 
H
S
 
P
A
 
R
E
 
R
A
 
N
V
 
I
A
 
E
K
 
K
M
 
M
A
 
A
G
 
S
G
 
G
V
 
E
P
 
P
L
 
L
T
 
N
D
 
D
A
 
D
D
 
D
R
 
R
L
 
K
P
 
P
W
 
W
L
 
L
R
 
Q
K
 
A
V
 
L
A
 
N
A
 
D
W
 
A
I
 
A
D
 
F
G
 
A
R
 
M
L
 
Q
E
 
R
S
 
T
G
 
N
G
 
K
Q
 
V
G
 
S
V
 
L
M
 
I
A
 
V
C
 
C
S
 
S
A
 
A
L
 
L
K
 
K
R
 
K
S
 
H
Y
 
Y
R
 
R
R
 
D
M
 
L
L
 
L
V
 
R
H
 
E
D
 
G
V
 
N
E
 
P
R
 
N
V
 
L
R
 
S
L
 
F
V
 
I
H
 
Y
L
 
L
S
 
K
A
 
G
D
 
D
R
 
F
A
 
D
L
 
V
L
 
I
Q
 
E
R
 
S
R
 
R
L
|
L
T
 
K
E
 
A
R
 
R
T
 
K
G
 
G
H
 
H
F
 
F
F
 
F
K
 
K
A
 
T
S
 
Q
M
 
M
L
 
L
D
 
V
S
 
T
Q
 
Q
L
 
F
R
 
E
D
 
T
L
 
L
E
 
Q
P
 
E
P
 
P
A
 
G
A
 
A
D
 
D
E
 
E
R
 
T
A
 
D
V
 
V
T
 
L
V
 
V
T
 
-
V
 
V
T
 
D
A
 
I
D
 
D
Q
 
Q
T
 
P
P
 
L
H
 
E
Q
 
G
V
 
V
V
 
V
G
 
A
R
 
S
I
 
T
I
 
I
D
 
E
A
 
V
L
 
I

1ko5A Crystal structure of gluconate kinase (see paper)
38% identity, 91% coverage: 7:170/180 of query aligns to 7:169/172 of 1ko5A

query
sites
1ko5A
Q
 
H
V
 
I
V
 
Y
V
 
V
V
 
L
A
 
M
G
 
G
V
 
V
S
|
S
G
|
G
T
 
S
G
|
G
K
|
K
S
|
S
T
 
A
V
 
V
G
 
A
G
 
S
L
 
E
L
 
V
A
 
A
R
 
H
T
 
Q
L
 
L
G
 
H
W
 
A
E
 
A
F
 
F
A
 
L
D
 
D
A
 
G
D
 
D
D
 
F
L
 
L
H
 
H
S
 
P
A
 
R
E
 
R
A
 
N
V
 
I
A
 
E
K
 
K
M
 
M
A
 
A
G
 
S
G
 
G
V
 
E
P
 
P
L
 
L
T
 
N
D
 
D
A
 
D
D
 
D
R
 
R
L
 
K
P
 
P
W
 
W
L
 
L
R
 
Q
K
 
A
V
 
L
A
 
N
A
 
D
W
 
A
I
 
A
D
 
F
G
 
A
R
 
M
L
 
Q
E
 
R
S
 
T
G
 
N
G
 
K
Q
 
V
G
 
S
V
 
L
M
 
I
A
 
V
C
 
C
S
 
S
A
 
A
L
 
L
K
 
K
R
 
K
S
 
H
Y
 
Y
R
 
R
R
 
D
M
 
L
L
 
L
V
 
R
H
 
E
D
 
G
V
 
N
E
 
P
R
 
N
V
 
L
R
 
S
L
 
F
V
 
I
H
 
Y
L
 
L
S
 
K
A
 
G
D
 
D
R
 
F
A
 
D
L
 
V
L
 
I
Q
 
E
R
 
S
R
|
R
L
 
L
T
 
K
E
 
A
R
|
R
T
 
K
G
 
G
H
 
H
F
 
F
F
 
F
K
 
K
A
 
T
S
 
Q
M
 
M
L
 
L
D
 
V
S
 
T
Q
 
Q
L
 
F
R
 
E
D
 
T
L
 
L
E
 
Q
P
 
E
P
 
P
A
 
G
A
 
A
D
 
D
E
 
E
R
 
T
A
 
D
V
 
V
T
 
L
V
 
V
T
 
-
V
 
V
T
 
D
A
 
I
D
 
D
Q
 
Q
T
 
P
P
x
L
H
 
E
Q
 
G
V
 
V
V
 
V
G
 
A
R
 
S
I
 
T
I
 
I
D
 
E
A
 
V
L
 
I

1kofA Crystal structure of gluconate kinase (see paper)
38% identity, 91% coverage: 7:170/180 of query aligns to 7:169/171 of 1kofA

query
sites
1kofA
Q
 
H
V
 
I
V
 
Y
V
 
V
V
 
L
A
 
M
G
 
G
V
 
V
S
|
S
G
|
G
T
 
S
G
|
G
K
|
K
S
|
S
T
x
A
V
 
V
G
 
A
G
 
S
L
 
E
L
 
V
A
 
A
R
 
H
T
 
Q
L
 
L
G
 
H
W
 
A
E
 
A
F
 
F
A
 
L
D
 
D
A
 
G
D
 
D
D
 
F
L
 
L
H
 
H
S
 
P
A
 
R
E
 
R
A
 
N
V
 
I
A
 
E
K
 
K
M
 
M
A
 
A
G
 
S
G
 
G
V
 
E
P
 
P
L
 
L
T
 
N
D
 
D
A
 
D
D
 
D
R
 
R
L
 
K
P
 
P
W
 
W
L
 
L
R
 
Q
K
 
A
V
 
L
A
 
N
A
 
D
W
 
A
I
 
A
D
 
F
G
 
A
R
 
M
L
 
Q
E
 
R
S
 
T
G
 
N
G
 
K
Q
 
V
G
 
S
V
 
L
M
 
I
A
 
V
C
 
C
S
 
S
A
 
A
L
 
L
K
 
K
R
 
K
S
 
H
Y
 
Y
R
 
R
R
 
D
M
 
L
L
 
L
V
 
R
H
 
E
D
 
G
V
 
N
E
 
P
R
 
N
V
 
L
R
 
S
L
 
F
V
 
I
H
 
Y
L
 
L
S
 
K
A
 
G
D
 
D
R
 
F
A
 
D
L
 
V
L
 
I
Q
 
E
R
 
S
R
|
R
L
 
L
T
 
K
E
 
A
R
 
R
T
 
K
G
 
G
H
 
H
F
 
F
F
 
F
K
 
K
A
 
T
S
 
Q
M
 
M
L
 
L
D
 
V
S
 
T
Q
 
Q
L
 
F
R
 
E
D
 
T
L
 
L
E
 
Q
P
 
E
P
 
P
A
 
G
A
 
A
D
 
D
E
 
E
R
 
T
A
 
D
V
 
V
T
 
L
V
 
V
T
 
-
V
 
V
T
 
D
A
 
I
D
 
D
Q
 
Q
T
 
P
P
x
L
H
 
E
Q
 
G
V
 
V
V
 
V
G
 
A
R
 
S
I
 
T
I
 
I
D
 
E
A
 
V
L
 
I

Query Sequence

>WP_012854191.1 NCBI__GCF_000024385.1:WP_012854191.1
MPAPLPQVVVVAGVSGTGKSTVGGLLARTLGWEFADADDLHSAEAVAKMAGGVPLTDADR
LPWLRKVAAWIDGRLESGGQGVMACSALKRSYRRMLVHDVERVRLVHLSADRALLQRRLT
ERTGHFFKASMLDSQLRDLEPPAADERAVTVTVTADQTPHQVVGRIIDALGLHRPRAAGH

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory