SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_012964546.1 NCBI__GCF_000025505.1:WP_012964546.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

Q58487 Mevalonate kinase; MK; MVK; EC 2.7.1.36 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
25% identity, 75% coverage: 23:227/273 of query aligns to 54:277/312 of Q58487

query
sites
Q58487
A
 
S
F
 
L
A
 
G
L
 
L
N
 
N
L
 
L
K
 
N
T
 
E
R
 
I
V
 
K
R
 
N
I
 
I
I
 
N
P
 
P
G
 
N
K
 
N
E
 
F
G
 
G
D
 
D
F
 
F
E
 
-
S
 
-
R
 
K
A
 
Y
L
 
C
E
 
L
C
 
C
V
 
A
V
 
I
K
 
K
K
 
N
V
 
T
F
 
L
R
 
D
S
 
Y
L
 
L
N
 
N
I
 
I
D
 
E
G
 
P
K
 
K
-
 
T
-
 
G
-
 
F
-
 
K
V
 
I
K
 
N
V
 
I
E
 
S
S
 
S
E
 
K
I
 
I
P
 
P
R
 
I
R
 
S
S
 
C
G
 
G
L
 
L
G
 
G
S
 
S
S
 
S
S
 
A
A
 
S
V
 
I
V
 
T
N
 
I
A
 
G
L
 
T
M
 
I
C
 
K
A
 
A
A
 
V
Y
 
S
K
 
G
Y
 
F
L
 
Y
N
 
N
K
 
K
E
 
E
L
 
L
E
 
K
A
 
D
H
 
D
S
 
E
I
 
I
L
 
A
R
 
K
A
 
L
N
 
G
A
 
Y
R
 
M
I
 
V
S
 
E
L
 
K
E
 
E
C
 
-
G
 
-
M
 
I
S
 
Q
Y
 
G
T
 
K
G
 
A
A
 
S
F
 
I
D
 
T
D
 
D
A
 
T
S
 
S
A
 
T
S
 
I
L
 
T
L
 
Y
G
 
K
G
 
G
V
 
I
V
 
L
F
 
E
S
 
I
D
 
K
N
 
N
A
 
N
K
 
K
M
 
F
K
 
R
L
 
K
F
 
I
K
 
K
-
 
G
-
 
E
-
 
F
R
 
E
E
 
E
S
 
F
L
 
L
E
 
K
G
 
N
K
 
C
A
 
K
A
 
F
I
 
L
L
 
I
I
 
V
P
 
Y
A
 
A
W
 
E
E
 
K
R
|
R
K
 
K
N
 
K
V
 
K
-
 
T
-
 
A
-
 
E
-
 
L
-
 
V
-
 
N
D
 
E
L
 
V
K
 
A
K
 
K
I
 
I
R
 
E
E
 
N
R
 
K
R
 
D
E
 
E
-
 
I
-
 
F
-
 
K
E
 
E
V
 
I
E
 
D
R
 
K
A
 
V
F
 
I
K
 
D
L
 
E
A
 
A
M
 
L
E
 
K
G
 
I
K
 
K
L
 
N
R
 
K
E
 
E
-
 
D
-
 
F
-
 
G
A
 
K
M
 
L
Y
 
M
V
 
T
N
 
K
S
 
N
Y
 
H
E
 
E
Y
 
L
C
 
L
R
 
K
A
 
K
L
 
L
N
 
N
L
 
I
P
 
S
-
 
T
-
 
P
-
 
K
F
 
L
E
 
D
P
 
R
V
 
I
V
 
V
A
 
D
A
 
I
Y
 
G
N
 
N
-
 
R
L
 
F
G
 
G
L
 
F
N
 
G
A
 
A
G
x
K
L
 
L
S
 
T
G
 
G
N
 
A
G
 
G

Query Sequence

>WP_012964546.1 NCBI__GCF_000025505.1:WP_012964546.1
MVEGKAFAAGTIVNALAALKGVAFALNLKTRVRIIPGKEGDFESRALECVVKKVFRSLNI
DGKVKVESEIPRRSGLGSSSAVVNALMCAAYKYLNKELEAHSILRANARISLECGMSYTG
AFDDASASLLGGVVFSDNAKMKLFKRESLEGKAAILIPAWERKNVDLKKIRERREEVERA
FKLAMEGKLREAMYVNSYEYCRALNLPFEPVVAAYNLGLNAGLSGNGPSYVAFGENVEDV
KSVWESFGKVIFVDIVNVPAEDVKISGSLFIQT

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory