Comparing WP_012966710.1 NCBI__GCF_000025505.1:WP_012966710.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 10 hits to proteins with known functional sites (download)
2qjgA M. Jannaschii adh synthase complexed with f1,6p (see paper)
44% identity, 93% coverage: 2:245/261 of query aligns to 10:259/272 of 2qjgA
P58315 Fructose-bisphosphate aldolase class 1; Fructose-bisphosphate aldolase class I; FBP aldolase; FBPA; EC 4.1.2.13 from Thermoproteus tenax (strain ATCC 35583 / DSM 2078 / JCM 9277 / NBRC 100435 / Kra 1) (see paper)
37% identity, 89% coverage: 1:231/261 of query aligns to 1:239/263 of P58315
2yceE Structure of an archaeal fructose-1,6-bisphosphate aldolase with the catalytic lys covalently bound to the carbinolamine intermediate of the substrate. (see paper)
36% identity, 86% coverage: 7:231/261 of query aligns to 5:237/255 of 2yceE
1w8sA The mechanism of the schiff base forming fructose-1,6-bisphosphate aldolase: structural analysis of reaction intermediates (see paper)
37% identity, 86% coverage: 7:231/261 of query aligns to 5:237/250 of 1w8sA
P58314 Fructose-bisphosphate aldolase class 1; Fructose-bisphosphate aldolase class I; FBP aldolase; EC 4.1.2.13 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see paper)
34% identity, 85% coverage: 17:239/261 of query aligns to 23:261/281 of P58314
P76143 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase; EC 2.3.1.245 from Escherichia coli (strain K12) (see paper)
29% identity, 92% coverage: 3:241/261 of query aligns to 35:271/291 of P76143
4p2vA Structure of the ai-2 processing enzyme lsrf in complex with the product of the lsrg reaction p-hpd (see paper)
29% identity, 92% coverage: 3:241/261 of query aligns to 27:263/281 of 4p2vA
3gndA Crystal structure of e. Coli lsrf in complex with ribulose-5-phosphate (see paper)
29% identity, 92% coverage: 3:241/261 of query aligns to 26:258/276 of 3gndA
3glcA Crystal structure of e. Coli lsrf in complex with ribose-5-phosphate (see paper)
29% identity, 92% coverage: 3:241/261 of query aligns to 26:258/276 of 3glcA
P0A991 Fructose-bisphosphate aldolase class 1; Fructose-bisphosphate aldolase class I; FBP aldolase; EC 4.1.2.13 from Escherichia coli (strain K12) (see 2 papers)
28% identity, 69% coverage: 70:250/261 of query aligns to 129:349/350 of P0A991
Sites not aligning to the query:
>WP_012966710.1 NCBI__GCF_000025505.1:WP_012966710.1
MVGKRRRLKKIFRNDLSLVVPMDHGITKPEAGLEKIDFLLERLDGLADAFVLHKGVVKHS
KYVEEMESALIVHLSASTSLSPDPNAKTIVTSVKKAVELGADAVSVHINVGSETEERQLK
EVGMVAEEADEYGVPLLVMSYPRGRGVDEKKVENVMHAARVAYELGADIIKTNYTGSAES
FSKVVEIVDVPVLIAGGNKKSFESFLMDVRNAIRAGAKGVAAGRNVFQAEDPRGVVMAIK
SAFKEALIGVGDEGALAAKQR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory