Comparing WP_012968216.1 NCBI__GCF_000025465.1:WP_012968216.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
29% identity, 96% coverage: 5:370/380 of query aligns to 11:383/383 of 7uoiA
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
30% identity, 91% coverage: 22:368/380 of query aligns to 29:378/381 of 8uw6B
Sites not aligning to the query:
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
30% identity, 71% coverage: 2:269/380 of query aligns to 3:276/375 of 4pqaA
Sites not aligning to the query:
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
30% identity, 71% coverage: 2:269/380 of query aligns to 3:276/376 of 4o23A
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
28% identity, 70% coverage: 5:269/380 of query aligns to 6:276/377 of P44514
Sites not aligning to the query:
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
28% identity, 70% coverage: 5:269/380 of query aligns to 10:280/380 of 5vo3A
Sites not aligning to the query:
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
28% identity, 64% coverage: 26:269/380 of query aligns to 25:276/377 of 7t1qA
Sites not aligning to the query:
7lgpB Dape enzyme from shigella flexneri
28% identity, 70% coverage: 4:269/380 of query aligns to 7:277/377 of 7lgpB
Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 6 papers)
23% identity, 94% coverage: 4:362/380 of query aligns to 12:387/408 of Q03154
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
34% identity, 42% coverage: 5:165/380 of query aligns to 8:168/258 of 4h2kA
Sites not aligning to the query:
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
25% identity, 59% coverage: 9:234/380 of query aligns to 26:276/426 of 3pfoA
Sites not aligning to the query:
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
23% identity, 94% coverage: 4:362/380 of query aligns to 12:386/407 of P37111
Sites not aligning to the query:
Q8P8J5 N-acetyl-L-citrulline deacetylase; ACDase; Acetylcitrulline deacetylase; EC 3.5.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
25% identity, 96% coverage: 1:365/380 of query aligns to 5:362/366 of Q8P8J5
3rzaA Crystal structure of a tripeptidase (sav1512) from staphylococcus aureus subsp. Aureus mu50 at 2.10 a resolution
27% identity, 79% coverage: 49:347/380 of query aligns to 55:349/373 of 3rzaA
Sites not aligning to the query:
2f7vA Structure of acetylcitrulline deacetylase complexed with one co (see paper)
25% identity, 96% coverage: 1:365/380 of query aligns to 6:357/360 of 2f7vA
P45494 Beta-Ala-Xaa dipeptidase; Beta-Ala-His dipeptidase; Peptidase V; EC 3.4.13.- from Lactobacillus delbrueckii subsp. lactis (see paper)
30% identity, 43% coverage: 25:189/380 of query aligns to 47:203/470 of P45494
Sites not aligning to the query:
1lfwA Crystal structure of pepv (see paper)
30% identity, 43% coverage: 25:189/380 of query aligns to 47:203/468 of 1lfwA
Sites not aligning to the query:
4op4B Crystal structure of the catalytic domain of dape protein from v.Cholerea in the zn bound form (see paper)
31% identity, 43% coverage: 5:169/380 of query aligns to 6:170/265 of 4op4B
Sites not aligning to the query:
O04373 IAA-amino acid hydrolase ILR1-like 4; jasmonoyl-L-amino acid hydrolase; EC 3.5.1.-; EC 3.5.1.127 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
24% identity, 47% coverage: 126:303/380 of query aligns to 158:363/440 of O04373
5k8pA Zn2+/tetrahedral intermediate-bound r289a 5-nitroanthranilate aminohydrolase (see paper)
21% identity, 67% coverage: 19:271/380 of query aligns to 30:317/421 of 5k8pA
Sites not aligning to the query:
>WP_012968216.1 NCBI__GCF_000025465.1:WP_012968216.1
MTTTLELARQLLGFNTINPPGSEADCMRFFADWLDESGFEVSLSSFGEGRCNLIASLPGA
KSGKPLAFTGHLDTVPLGNARWQYDPFGSQMEDGRLYGRGSSDMKAAIAAFAVACVHQRE
AILAGRGAVLLITGGEETGCDGARALIASATLPEVGALIVGEPTANYPVIGHKGALWLRC
ETRGKTAHGAMPELGINAIYLAADALGKIQHFSPGAPHPLMKQPTLNVGRIEGGLNINSV
PDRTRFDVDIRSAPNLQHATIRERLTTLLGESVTVSTLVDLPAVLSREDHAWIKQVYQRC
QPLHAEPIAPRVVPYFTDASLLLPALGDPPCIILGPGEPSMAHQTDEYCLLSRLAEAEQL
YGDIIRDWMASPPATKVKNE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory