Comparing WP_012969211.1 NCBI__GCF_000025465.1:WP_012969211.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
91% identity, 99% coverage: 3:383/383 of query aligns to 1:381/381 of 8uw6B
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
29% identity, 78% coverage: 63:362/383 of query aligns to 56:363/383 of 7uoiA
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
30% identity, 64% coverage: 9:253/383 of query aligns to 10:250/380 of 5vo3A
Sites not aligning to the query:
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
30% identity, 64% coverage: 9:253/383 of query aligns to 6:246/377 of P44514
Sites not aligning to the query:
Q8P8J5 N-acetyl-L-citrulline deacetylase; ACDase; Acetylcitrulline deacetylase; EC 3.5.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
26% identity, 78% coverage: 80:378/383 of query aligns to 72:363/366 of Q8P8J5
2f7vA Structure of acetylcitrulline deacetylase complexed with one co (see paper)
25% identity, 78% coverage: 80:378/383 of query aligns to 73:358/360 of 2f7vA
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
33% identity, 44% coverage: 8:174/383 of query aligns to 7:170/258 of 4h2kA
Sites not aligning to the query:
7lgpB Dape enzyme from shigella flexneri
30% identity, 64% coverage: 7:253/383 of query aligns to 6:247/377 of 7lgpB
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
26% identity, 90% coverage: 38:380/383 of query aligns to 28:374/377 of 7t1qA
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
26% identity, 64% coverage: 9:253/383 of query aligns to 6:246/376 of 4o23A
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
26% identity, 64% coverage: 9:253/383 of query aligns to 6:246/375 of 4pqaA
Sites not aligning to the query:
2pokA Crystal structure of a m20 family metallo peptidase from streptococcus pneumoniae
34% identity, 31% coverage: 8:125/383 of query aligns to 23:137/458 of 2pokA
Sites not aligning to the query:
1cg2A Carboxypeptidase g2 (see paper)
28% identity, 60% coverage: 37:264/383 of query aligns to 43:263/389 of 1cg2A
Sites not aligning to the query:
P06621 Carboxypeptidase G2; CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase; EC 3.4.17.11 from Pseudomonas sp. (strain RS-16) (see paper)
28% identity, 60% coverage: 37:264/383 of query aligns to 68:288/415 of P06621
Sites not aligning to the query:
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
27% identity, 52% coverage: 75:272/383 of query aligns to 75:283/407 of P37111
Sites not aligning to the query:
7m6uB Crystal structure of a circular permutation and computationally designed pro-enzyme of carboxypeptidase g2 (see paper)
30% identity, 51% coverage: 69:264/383 of query aligns to 11:198/392 of 7m6uB
Sites not aligning to the query:
Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 6 papers)
25% identity, 54% coverage: 73:278/383 of query aligns to 73:290/408 of Q03154
Sites not aligning to the query:
P45494 Beta-Ala-Xaa dipeptidase; Beta-Ala-His dipeptidase; Peptidase V; EC 3.4.13.- from Lactobacillus delbrueckii subsp. lactis (see paper)
33% identity, 31% coverage: 57:176/383 of query aligns to 62:182/470 of P45494
Sites not aligning to the query:
4op4B Crystal structure of the catalytic domain of dape protein from v.Cholerea in the zn bound form (see paper)
29% identity, 43% coverage: 7:172/383 of query aligns to 4:166/265 of 4op4B
Sites not aligning to the query:
1lfwA Crystal structure of pepv (see paper)
33% identity, 31% coverage: 57:176/383 of query aligns to 62:182/468 of 1lfwA
Sites not aligning to the query:
>WP_012969211.1 NCBI__GCF_000025465.1:WP_012969211.1
MKNNLPPFIEIYRALIATPSISATEEALDQSNESLINLLAGWFRDLGFNVEIQPVPDTRH
KFNLLASTGHGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFI
LDALRDVDVTTLKKPLYILATADEETSMAGARYFAETTQLRPDCAIIGEPTSLQPIRAHK
GHMSNAIRIQGQSGHSSDPARGVNAIELMHDAIGRIMQLRDLLKERYHFEAFTVPYPTLN
LGAIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLGEALAPVSERWPGRLTVSELHP
PIPGYECPPDHKLVQVVEKLLGAQTDVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEY
LETRFIKPTRELISQVVHHFCWH
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory