SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_012974726.1 NCBI__GCF_000010725.1:WP_012974726.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

6j2lA Crystal structure of bi-functional enzyme (see paper)
49% identity, 61% coverage: 5:69/106 of query aligns to 114:178/200 of 6j2lA

query
sites
6j2lA
L
 
L
I
 
Y
R
 
Q
L
 
L
Y
 
E
A
 
Q
A
 
L
I
 
L
L
 
A
D
 
E
R
 
R
K
 
K
R
 
Y
M
 
A
D
 
D
P
 
P
A
 
E
Q
 
T
S
 
S
K
 
Y
T
 
T
A
 
A
R
 
K
L
 
L
I
 
Y
A
 
A
A
 
S
G
 
G
P
 
T
K
 
K
K
 
R
I
 
I
A
 
A
K
 
Q
K
 
K
V
 
V
G
 
G
E
 
E
E
|
E
A
 
G
V
 
V
E
 
E
V
 
T
A
 
A
L
 
L
D
 
A
A
 
A
M
 
T
N
 
V
E
 
H
D
 
D
R
 
R
E
 
F
G
 
E
V
 
L
I
 
T
N
 
N
E
|
E
S
 
A
A
 
S
D
|
D
L
 
L
L
 
M
Y
 
Y
N
 
H

Sites not aligning to the query:

6j2lB Crystal structure of bi-functional enzyme (see paper)
53% identity, 46% coverage: 21:69/106 of query aligns to 115:163/185 of 6j2lB

query
sites
6j2lB
A
 
A
Q
 
E
S
 
R
K
 
K
T
 
Y
A
 
A
R
 
D
L
 
L
I
 
Y
A
 
A
A
 
S
G
 
G
P
 
T
K
 
K
K
 
R
I
 
I
A
 
A
K
 
Q
K
 
K
V
 
V
G
 
G
E
 
E
E
|
E
A
 
G
V
 
V
E
|
E
V
 
T
A
 
A
L
 
L
D
 
A
A
 
A
M
 
T
N
 
V
E
 
H
D
 
D
R
 
R
E
 
F
G
 
E
V
 
L
I
 
T
N
 
N
E
|
E
S
 
A
A
 
S
D
|
D
L
 
L
L
 
M
Y
 
Y
N
 
H

Sites not aligning to the query:

Query Sequence

>WP_012974726.1 NCBI__GCF_000010725.1:WP_012974726.1
MTDDLIRLYAAILDRKRMDPAQSKTARLIAAGPKKIAKKVGEEAVEVALDAMNEDREGVI
NESADLLYNLSVLWATLKIHPDEVFAEIRRREALYGIAEKLPKTAA

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory