Comparing WP_012991136.1 NCBI__GCF_000025605.1:WP_012991136.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 8 hits to proteins with known functional sites (download)
1qxoA Crystal structure of chorismate synthase complexed with oxidized fmn and epsp (see paper)
54% identity, 99% coverage: 3:387/387 of query aligns to 1:388/388 of 1qxoA
P0A2Y6 Chorismate synthase; CS; 5-enolpyruvylshikimate-3-phosphate phospholyase; EC 4.2.3.5 from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) (see paper)
54% identity, 99% coverage: 3:387/387 of query aligns to 1:388/388 of P0A2Y6
P9WPY1 Chorismate synthase; CS; 5-enolpyruvylshikimate-3-phosphate phospholyase; EC 4.2.3.5 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
49% identity, 99% coverage: 3:384/387 of query aligns to 2:389/401 of P9WPY1
2qhfA Mycobacterium tuberculosis chorismate synthase in complex with nca
49% identity, 99% coverage: 3:384/387 of query aligns to 2:389/392 of 2qhfA
2o12A Mycobacterium tuberculosis chorismate synthase in complex with fmn
48% identity, 99% coverage: 3:384/387 of query aligns to 2:383/386 of 2o12A
1um0A Crystal structure of chorismate synthase complexed with fmn (see paper)
34% identity, 94% coverage: 3:365/387 of query aligns to 8:351/365 of 1um0A
P56122 Chorismate synthase; CS; 5-enolpyruvylshikimate-3-phosphate phospholyase; EC 4.2.3.5 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see paper)
34% identity, 94% coverage: 3:365/387 of query aligns to 8:351/365 of P56122
Q12640 Chorismate synthase aro-2; 5-enolpyruvylshikimate-3-phosphate phospholyase; EC 1.5.1.38; EC 4.2.3.5 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 3 papers)
33% identity, 94% coverage: 3:364/387 of query aligns to 8:393/432 of Q12640
>WP_012991136.1 NCBI__GCF_000025605.1:WP_012991136.1
MSIRFLTAGESHGQALVCILEGIPANLELSAEDINRDLRRRQKGYGRGGRMKIEQDQVEI
LSGVRFGKTTGAPIALLIKNRDWENWKEKMAVEGERPSSAVPFTRPRPGHADLAGGIKYN
QRDLRNILERASARETACRCAVGAVCKKFLQELGIKVGSYVVSIGSLSPPIQEEDLEKRH
LLAEESVVRFPDPTKDPLFMELIDEAKQMGESLGGVFEVFALNVPPGLGSHTQWDRRIDG
RIAQAMMSIQAIKGVEIGLGFEAAKRKGSQVHDEIGWDPERGFFRYTNHLGGTEGGVTNG
MPILVRCAMKPIPTLARPLRSVDIQTKEEVSAGKERTDVVAVPAASVVGEAMLAFVVAQA
LLEKLGGDFMEEIKERYARYLEYVKSF
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory