SitesBLAST
Comparing WP_013010594.1 NCBI__GCF_000025725.1:WP_013010594.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
7omlA Bacillus subtilis phosphoglucomutase glmm (metal bound) (see paper)
49% identity, 97% coverage: 3:442/454 of query aligns to 2:436/445 of 7omlA
7ojrA Bacillus subtilis phosphoglucomutase glmm (phosphate bound) (see paper)
49% identity, 97% coverage: 3:442/454 of query aligns to 2:436/445 of 7ojrA
P31120 Phosphoglucosamine mutase; EC 5.4.2.10 from Escherichia coli (strain K12) (see 3 papers)
47% identity, 99% coverage: 2:450/454 of query aligns to 4:445/445 of P31120
- S100 (= S100) mutation to A: 2% of wild-type activity.; mutation to T: 20-fold increase in the non-specific phosphoglucomutase activity towards glucose-phosphate substrates (non aminated).
- S102 (= S102) active site, Phosphoserine intermediate; modified: Phosphoserine; by autocatalysis; mutation to A: Loss of activity in the absence or presence of glucosamine-1,6-diP.
Sites not aligning to the query:
- 1 modified: Initiator methionine, Removed
3i3wA Structure of a phosphoglucosamine mutase from francisella tularensis
42% identity, 96% coverage: 3:440/454 of query aligns to 1:430/441 of 3i3wA
- active site: R9 (= R11), S99 (= S102), H100 (= H103), K109 (= K112), D237 (= D245), D239 (= D247), D241 (= D249), R242 (= R250), H324 (= H334)
- binding zinc ion: S99 (= S102), D237 (= D245), D239 (= D247), D241 (= D249)
1wqaA Crystal structure of pyrococcus horikoshii phosphomannomutase/phosphoglucomutase complexed with mg2+
34% identity, 96% coverage: 1:438/454 of query aligns to 1:442/455 of 1wqaA
- active site: R11 (= R11), S101 (= S102), H102 (= H103), K111 (= K112), D243 (= D245), D245 (= D247), D247 (= D249), R248 (= R250), G330 (≠ H334), R340 (≠ G344)
- binding magnesium ion: S101 (= S102), D243 (= D245), D245 (= D247), D247 (= D249)
6mlwA Crystal structure of x. Citri phosphoglucomutase in complex with 2- fluoro mannosyl-1-methyl-phosphonic acid (see paper)
26% identity, 92% coverage: 10:428/454 of query aligns to 12:428/449 of 6mlwA
- active site: R13 (= R11), S98 (= S102), H99 (= H103), K108 (= K112), D238 (= D245), D240 (= D247), D242 (= D249), R243 (= R250), H325 (= H334)
- binding 2,6-anhydro-5,7-dideoxy-5-fluoro-7-phosphono-D-glycero-D-manno-heptitol: G303 (= G312), H304 (≠ D313), E321 (= E330), S323 (= S332), H325 (= H334), R415 (= R415), S417 (= S417), N418 (≠ G418), T419 (= T419), R424 (= R424)
- binding magnesium ion: S98 (= S102), D238 (= D245), D240 (= D247), D242 (= D249)
5bmpA Crystal structure of phosphoglucomutase from xanthomonas citri complexed with glucose-1-phosphate (see paper)
26% identity, 92% coverage: 10:428/454 of query aligns to 12:428/449 of 5bmpA
- active site: R13 (= R11), S98 (= S102), H99 (= H103), K108 (= K112), D238 (= D245), D240 (= D247), D242 (= D249), R243 (= R250), H325 (= H334)
- binding 1-O-phosphono-alpha-D-glucopyranose: R281 (≠ M290), G303 (= G312), E321 (= E330), S323 (= S332), H325 (= H334), R415 (= R415), S417 (= S417), N418 (≠ G418), T419 (= T419), R424 (= R424)
- binding magnesium ion: S98 (= S102), D238 (= D245), D240 (= D247), D242 (= D249)
6nqhA Xanthomonas citri dephospho-pgm in complex with xylose-1-phosphate
26% identity, 92% coverage: 10:428/454 of query aligns to 11:427/448 of 6nqhA
- active site: R12 (= R11), S97 (= S102), H98 (= H103), K107 (= K112), D237 (= D245), D239 (= D247), D241 (= D249), R242 (= R250), H324 (= H334)
- binding magnesium ion: D237 (= D245), D239 (= D247), D241 (= D249)
- binding 1-O-phosphono-alpha-D-xylopyranose: R12 (= R11), S97 (= S102), H98 (= H103), K107 (= K112), D239 (= D247), R242 (= R250), R280 (≠ M290), S301 (≠ V311), G302 (= G312), E320 (= E330), S322 (= S332), H324 (= H334), R414 (= R415), S416 (= S417), N417 (≠ G418), T418 (= T419), R423 (= R424)
6np8A Xanthomonas citri phospho-pgm in complex with mannose-6-phosphate (see paper)
26% identity, 92% coverage: 10:428/454 of query aligns to 11:427/448 of 6np8A
- active site: R12 (= R11), S97 (= S102), H98 (= H103), K107 (= K112), D237 (= D245), D239 (= D247), D241 (= D249), R242 (= R250), H324 (= H334)
- binding calcium ion: S97 (= S102), D237 (= D245), D239 (= D247), D241 (= D249)
- binding 6-O-phosphono-alpha-D-mannopyranose: R280 (≠ M290), G302 (= G312), H303 (≠ D313), E320 (= E330), S322 (= S332), H324 (= H334), R414 (= R415), S416 (= S417), N417 (≠ G418), T418 (= T419), R423 (= R424)
Sites not aligning to the query:
6nolA Xanthomonas citri dephospho-pgm in complex with mannose-1-phosphate (see paper)
26% identity, 92% coverage: 10:428/454 of query aligns to 11:427/448 of 6nolA
- active site: R12 (= R11), S97 (= S102), H98 (= H103), K107 (= K112), D237 (= D245), D239 (= D247), D241 (= D249), R242 (= R250), H324 (= H334)
- binding 1-O-phosphono-alpha-D-mannopyranose: G302 (= G312), E320 (= E330), S322 (= S332), H324 (= H334), R414 (= R415), S416 (= S417), N417 (≠ G418), T418 (= T419), R423 (= R424)
- binding magnesium ion: S97 (= S102), D237 (= D245), D239 (= D247), D241 (= D249)
6nnpA Xanthomonas citri dephospho-pgm in complex with glucose-6-phosphate (see paper)
26% identity, 92% coverage: 10:428/454 of query aligns to 11:427/448 of 6nnpA