Comparing WP_013011617.1 NCBI__GCF_000025725.1:WP_013011617.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 9 hits to proteins with known functional sites (download)
P36683 Aconitate hydratase B; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; 2-methyl-cis-aconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Escherichia coli (strain K12) (see 2 papers)
60% identity, 99% coverage: 3:840/850 of query aligns to 1:852/865 of P36683
1l5jA Crystal structure of e. Coli aconitase b. (see paper)
60% identity, 99% coverage: 3:840/850 of query aligns to 1:852/862 of 1l5jA
4kp1A Crystal structure of ipm isomerase large subunit from methanococcus jannaschii (mj0499) (see paper)
29% identity, 52% coverage: 369:807/850 of query aligns to 1:417/423 of 4kp1A
4nqyA The reduced form of mj0499 (see paper)
29% identity, 51% coverage: 371:807/850 of query aligns to 2:404/409 of 4nqyA
P19414 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
27% identity, 43% coverage: 439:807/850 of query aligns to 137:502/778 of P19414
Sites not aligning to the query:
O14289 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
26% identity, 31% coverage: 548:814/850 of query aligns to 168:479/758 of O14289
Sites not aligning to the query:
P39533 Homocitrate dehydratase, mitochondrial; Aconitase 2; EC 4.2.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
25% identity, 42% coverage: 453:806/850 of query aligns to 155:506/789 of P39533
Sites not aligning to the query:
2pkpA Crystal structure of 3-isopropylmalate dehydratase (leud)from methhanocaldococcus jannaschii dsm2661 (mj1271) (see paper)
25% identity, 21% coverage: 165:345/850 of query aligns to 4:166/167 of 2pkpA
Q58667 Methanogen homoaconitase small subunit; HACN; Homoaconitate hydratase; EC 4.2.1.114 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
25% identity, 21% coverage: 165:345/850 of query aligns to 4:166/170 of Q58667
>WP_013011617.1 NCBI__GCF_000025725.1:WP_013011617.1
MTMMQDYLKQVEDRAKMGIPALPLTAEFTAEVCKLLEQKPTAELVDLIENRVAPGVDPAS
EVKADWLGKVAKGETACSLISRERAVFLLGTMLGGYNVKYLVELLTDKELGDDAAEALKK
TILVYNAFDEIVALAKTNANAMAVLKSWADAEWFTNKPELRKEYKVKIYKVAGETNTDDF
SPAKHAWSRPDIPLHALAMGETGFPDGNEVMEKYKAEGFEVAFVGDVVGTGSSRKSACNS
VMWRIGSDIPFVPNKRNGGTIIGSVIAPIFFNTTEDSGGLPIICNVDELNTGDVVIINTE
KGEITDESGKVLSTFELKPSTIKDEYRAGGRLNLIIGRTLTNNARKALGLGESDVFKKAV
NPTPKADQGYTLAQKIIGKAAGVDGVLPGTACEPKMTTVGSQDTTGPMTRDEIKELACLE
FQSPMFMQSFCHTAAYPKKADVDMHKSLPQFVSERKGVSLRPGDGVIHSWLNRLLLPDTL
GTGGDSHTRFPMGLSLPAGSGLVAFAGALGFMPLDVPESVLVKFKGDFNPGITLRDAVNA
IPYWAIKQGLLTVPKKNKKNIFNGRILEMEGLPNLTVEQAFELTDATAERSAAGGTIKLS
EESVANYLKSNIALMKKMIEAGYQHAETLKKRIEDCEAWLANPKLLERDENAEYAAVIEI
DLAEITEPILACPNDPDDVKLLSDIAGTKIDETFIGSCMTNIGHFRAAGKIWEGEAYPKT
RMWMTPPTRMDEMQLMEEGYYSIFSSVGARTEIPGCSLCMGNQGRVAPKAFVLSTSTRNF
PNRIGDESQVFLGSAELTAITALCGELPTKEKYFELFEKKVTPNKEEIYKYLEFDKMGDF
ELSYIETVAF
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory