Comparing WP_013011633.1 NCBI__GCF_000025725.1:WP_013011633.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P0ABK5 Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine sulfhydrylase A; S-carboxymethylcysteine synthase; Sulfate starvation-induced protein 5; SSI5; EC 2.5.1.47; EC 4.5.1.5 from Escherichia coli (strain K12) (see 5 papers)
59% identity, 99% coverage: 2:313/315 of query aligns to 3:312/323 of P0ABK5
Sites not aligning to the query:
6z4nAAA structure of oass complexed with upar inhibitor (see paper)
59% identity, 99% coverage: 2:313/315 of query aligns to 4:313/321 of 6z4nAAA
P0A1E3 Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine sulfhydrylase A; EC 2.5.1.47 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
59% identity, 99% coverage: 2:313/315 of query aligns to 3:312/323 of P0A1E3
Sites not aligning to the query:
1d6sA Crystal structure of the k41a mutant of o-acetylserine sulfhydrylase complexed in external aldimine linkage with methionine (see paper)
58% identity, 99% coverage: 2:313/315 of query aligns to 2:311/322 of 1d6sA
1fcjA Crystal structure of oass complexed with chloride and sulfate (see paper)
58% identity, 96% coverage: 2:304/315 of query aligns to 2:302/302 of 1fcjA
5xoqA Crystal structure of o-acetylserine sulfhydrylase with bound transcription factor peptide inhibitor from planctomyces limnophilus
53% identity, 100% coverage: 1:314/315 of query aligns to 2:307/310 of 5xoqA
5dbhX Crystal structure of o-acetylserine sulfhydrylase from haemophilus influenzae in complex with reaction intermediate alpha-aminoacrylate
54% identity, 99% coverage: 3:314/315 of query aligns to 2:311/312 of 5dbhX
1y7lA O-acetylserine sulfhydrylase complex (see paper)
55% identity, 99% coverage: 3:313/315 of query aligns to 2:310/310 of 1y7lA
4zu6X Crystal structure of o-acetylserine sulfhydrylase from haemophilus influenzae in complex with pre-reactive o-acetyl serine, alpha- aminoacrylate reaction intermediate and peptide inhibitor at the resolution of 2.25a
54% identity, 99% coverage: 1:313/315 of query aligns to 1:309/309 of 4zu6X
4oreX Cyrstal structure of o-acetylserine sulfhydrylase ternary complex from haemophilus influenzae at 2.2 a
54% identity, 99% coverage: 3:313/315 of query aligns to 2:308/308 of 4oreX
2q3dA 2.2 a resolution crystal structure of o-acetylserine sulfhydrylase (oass) from mycobacterium tuberculosis in complex with the reaction intermediate alpha-aminoacrylate (see paper)
51% identity, 99% coverage: 1:313/315 of query aligns to 1:305/306 of 2q3dA
P9WP55 O-acetylserine sulfhydrylase; OAS sulfhydrylase; OASS; Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine-specific cysteine synthase; Sulfide-dependent cysteine synthase; EC 2.5.1.47 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
51% identity, 99% coverage: 1:313/315 of query aligns to 1:305/310 of P9WP55
3zeiA Structure of the mycobacterium tuberculosis o-acetylserine sulfhydrylase (oass) cysk1 in complex with a small molecule inhibitor (see paper)
51% identity, 98% coverage: 1:308/315 of query aligns to 1:300/300 of 3zeiA
2q3cA 2.1 a resolution crystal structure of o-acetylserine sulfhydrylase (oass) holoenzyme from mycobacterium tuberculosis in complex with the inhibitory peptide dfsi (see paper)
51% identity, 98% coverage: 1:308/315 of query aligns to 1:300/300 of 2q3cA
6kr5B Crystal structure of o-acetyl serine sulfhydrylase isoform 3 from entamoeba histolytica (see paper)
48% identity, 99% coverage: 2:314/315 of query aligns to 10:318/336 of 6kr5B
4jblB Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with methionine (see paper)
47% identity, 100% coverage: 2:315/315 of query aligns to 11:320/335 of 4jblB
3bm5B Crystal structure of o-acetyl-serine sulfhydrylase from entamoeba histolytica in complex with cysteine (see paper)
47% identity, 100% coverage: 2:315/315 of query aligns to 11:320/335 of 3bm5B
3bm5A Crystal structure of o-acetyl-serine sulfhydrylase from entamoeba histolytica in complex with cysteine (see paper)
47% identity, 100% coverage: 2:315/315 of query aligns to 11:320/338 of 3bm5A
4jbnA Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with serine acetyl transferase derived tetrapeptide, spsi (see paper)
47% identity, 100% coverage: 2:315/315 of query aligns to 11:320/336 of 4jbnA
4il5A Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with isoleucine (see paper)
47% identity, 100% coverage: 2:315/315 of query aligns to 11:320/336 of 4il5A
>WP_013011633.1 NCBI__GCF_000025725.1:WP_013011633.1
MKIFENNSLTIGETPLVRLNSIQGKYKNNIFAKVEGRNPAYSVKCRVAAGIIKQGIESGK
LKEGMTIIEATSGNTGIGLSYAGAALGFKVAIIMPDTMTMERRMMMQAFGTELILTDGKL
GMKGAVALADEMVAKEPEKYFLANQFRNPANPLIHEATTGPEIFRDTDGKVDVFVSGVGT
GGTITGVSRYLKNEKGLNILTVAAEPVKSPVISQFIEKQPLQPGPHTIQGIGAGFIPETL
DVSLIDDVEQIDDENAKEYARRLAREEGIISGVSSGAAVCAAIQAIEKYKLEGKNIVVIL
PDSGERYLSSGLFQV
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory