Comparing WP_013089388.1 NCBI__GCF_000092885.1:WP_013089388.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
31% identity, 89% coverage: 43:405/410 of query aligns to 30:378/381 of 8uw6B
Sites not aligning to the query:
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
29% identity, 73% coverage: 91:388/410 of query aligns to 72:364/383 of 7uoiA
Q8P8J5 N-acetyl-L-citrulline deacetylase; ACDase; Acetylcitrulline deacetylase; EC 3.5.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
28% identity, 90% coverage: 25:391/410 of query aligns to 8:351/366 of Q8P8J5
2f7vA Structure of acetylcitrulline deacetylase complexed with one co (see paper)
28% identity, 90% coverage: 25:391/410 of query aligns to 9:346/360 of 2f7vA
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
28% identity, 79% coverage: 80:402/410 of query aligns to 53:371/377 of P44514
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
28% identity, 79% coverage: 80:402/410 of query aligns to 57:375/380 of 5vo3A
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
33% identity, 50% coverage: 91:296/410 of query aligns to 64:272/377 of 7t1qA
Sites not aligning to the query:
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
31% identity, 47% coverage: 89:282/410 of query aligns to 62:258/375 of 4pqaA
Sites not aligning to the query:
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
31% identity, 47% coverage: 89:282/410 of query aligns to 62:258/376 of 4o23A
7lgpB Dape enzyme from shigella flexneri
26% identity, 79% coverage: 83:405/410 of query aligns to 60:375/377 of 7lgpB
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
26% identity, 74% coverage: 89:391/410 of query aligns to 99:406/426 of 3pfoA
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
38% identity, 26% coverage: 89:193/410 of query aligns to 64:172/258 of 4h2kA
Sites not aligning to the query:
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
24% identity, 53% coverage: 85:301/410 of query aligns to 71:294/407 of P37111
Sites not aligning to the query:
4op4B Crystal structure of the catalytic domain of dape protein from v.Cholerea in the zn bound form (see paper)
38% identity, 24% coverage: 90:189/410 of query aligns to 63:166/265 of 4op4B
Sites not aligning to the query:
Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 6 papers)
23% identity, 52% coverage: 85:299/410 of query aligns to 71:293/408 of Q03154
Sites not aligning to the query:
4mmoA The crystal structure of a m20 family metallo-carboxypeptidase sso-cp2 from sulfolobus solfataricus
27% identity, 50% coverage: 46:249/410 of query aligns to 31:234/437 of 4mmoA
5xoyA Crystal structure of lysk from thermus thermophilus in complex with lysine (see paper)
24% identity, 79% coverage: 83:406/410 of query aligns to 51:338/341 of 5xoyA
Q8C165 N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Peptidase M20 domain-containing protein 1; PM20D1; EC 3.5.1.114; EC 3.5.1.14 from Mus musculus (Mouse) (see paper)
30% identity, 42% coverage: 48:218/410 of query aligns to 81:264/503 of Q8C165
Sites not aligning to the query:
1lfwA Crystal structure of pepv (see paper)
34% identity, 34% coverage: 70:207/410 of query aligns to 65:197/468 of 1lfwA
Sites not aligning to the query:
P45494 Beta-Ala-Xaa dipeptidase; Beta-Ala-His dipeptidase; Peptidase V; EC 3.4.13.- from Lactobacillus delbrueckii subsp. lactis (see paper)
34% identity, 34% coverage: 70:207/410 of query aligns to 65:197/470 of P45494
Sites not aligning to the query:
>WP_013089388.1 NCBI__GCF_000092885.1:WP_013089388.1
MSHVAETAQSSQSSASSASPASPVSLPWVTRLVSMDTVSRNPNLGLIETVRDELRAVGID
ATLTHGKGGKWANLFATIPAHDGETNGGVVLSGHTDVVPVDGQQWDSDPFKPEIRGDKLY
GRGSCDMKGFIGAALALVPDMQRAKLAKPIHLALSFDEEVGCVGAPLMIADLMKRGVKPD
GCIVGEPTSMRPIIAHKGINAYQCCVRGQAAHSSLTPKGLNAIEYAARLICYIRDMADQF
REQGPFDELYDVPFSTAQTSTITGGNAINTVPAECQFQFEFRNLPTLDPEQIFARIDSYA
RDTLLPKMLREHPSAAIEITKIAAAPGLDSSEQAAITQLVRALTADQDKRKVAYGTEAGL
FSNAGIPSIVCGPGDIQQAHKANEFVELAQLVACERFLRKFIHSMSVGAA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory