SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing WP_013090145.1 NCBI__GCF_000092885.1:WP_013090145.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 16 hits to proteins with known functional sites (download)

P0A9J8 Bifunctional chorismate mutase/prephenate dehydratase; Chorismate mutase-prephenate dehydratase; P-protein; EC 5.4.99.5; EC 4.2.1.51 from Escherichia coli (strain K12)
34% identity, 97% coverage: 9:356/359 of query aligns to 7:376/386 of P0A9J8

query
sites
P0A9J8

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R11 (= R13) mutation R->A,K: Important decrease in catalytic efficiency and affinity.
R28 (= R30) mutation R->A,K: Important decrease in catalytic efficiency and affinity.
K39 (= K41) mutation K->A,Q,R: Important decrease in catalytic efficiency and affinity.
E52 (= E54) mutation E->A,D,Q: Important decrease in catalytic efficiency and affinity.
Q88 (≠ E89) mutation Q->A,E,K: Important decrease in catalytic efficiency and affinity.

2qmxA The crystal structure of l-phe inhibited prephenate dehydratase from chlorobium tepidum tls (see paper)
38% identity, 73% coverage: 95:355/359 of query aligns to 5:273/278 of 2qmxA

query
sites
2qmxA

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active site: T169 (= T260), F171 (= F262)
binding phenylalanine: N204 (= N286), E205 (= E287), L209 (≠ M291), D222 (≠ S304), L223 (≠ M305), T224 (= T306), K225 (≠ R307), S228 (= S310), Y238 (= Y320), F240 (= F322)

3mwbA The crystal structure of prephenate dehydratase in complex with l-phe from arthrobacter aurescens to 2.0a
36% identity, 74% coverage: 92:358/359 of query aligns to 1:277/306 of 3mwbA

query
sites
3mwbA

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active site: T176 (= T260), F178 (= F262)
binding phenylalanine: D205 (≠ E287), H206 (vs. gap), L210 (≠ M291), N223 (≠ S304), L224 (≠ M305), S225 (≠ T306), R226 (= R307), S229 (= S310), F241 (= F322)

3mwbB The crystal structure of prephenate dehydratase in complex with l-phe from arthrobacter aurescens to 2.0a
37% identity, 73% coverage: 96:358/359 of query aligns to 5:274/303 of 3mwbB

query
sites
3mwbB

Y

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active site: T176 (= T260), F178 (= F262)
binding magnesium ion: A155 (= A239), Q158 (≠ H242), L161 (= L245)
binding phenylalanine: D205 (≠ N286), H206 (≠ E287), L210 (≠ M291), N223 (≠ S304), L224 (≠ M305), S225 (≠ T306), R226 (= R307), I227 (≠ F308), Y236 (= Y320), F238 (= F322)

6vh5D Crystal structure of prephenate dehydratase from brucella melitensis biovar abortus 2308 in complex with phenylalanine
33% identity, 74% coverage: 90:355/359 of query aligns to 5:276/282 of 6vh5D

query
sites
6vh5D

R

K

S

T

I

N

K

R

A

I

A

S

Y

F

L

Q

G

G

P

E

V

A

G

G

T

A

Y

N

S

S

E

D

Q

T

A

A

M

C

H

R

E

N

Y

M

F

F

G

-

Q

P

S

D

I

M

E

E

G

P

L

L

P

P

C

C

P

P

S

T

I

F

D

E

E

D

V

A

F

F

R

N

S

A

V

V

E

E

A

T

G

G

A

A

D

D

Y

L

G

A

V

M

V

I

P

P

V

I

E

E

N

N

S

T

T

L

E

A

G

G

A

R

V

V

S

A

R

D

T

I

L

H

D

Y

L

L

L

P

Q

L

T

A

Q

D

L

M

T

H

I

I

G

V

G

G

E

E

L

Y

A

F

L

L

P

P

I

I

H

H

H

F

N

Q

L

L

L

M

T

V

Q

-

N

-

G

-

L

L

V

P

G

G

V

V

T

R

R

R

-

E

-

I

-

K

-

T

V

V

C

H

A

S

H

H

A

I

Q

H

A

A

L

L

A

G

Q

Q

C

C

Q

R

R

N

W

V

L

I

S

R

T

Q

N

N

A

G

P

-

H

-

L

W

E

K

R

G

Q

V

A

I

V

A

S

G

S

D

N

T

A

A

E

G

A

A

R

R

M

L

A

V

S

A

E

D

-

V

-

K

D

D

P

R

T

S

V

M

A

A

I

L

A

A

G

P

D

R

R

L

A

A

I

D

H

L

Y

Y

G

G

L

L

Q

D

V

I

T

L

N

E

A

E

L

N

I

V

Q

E

D

D

D

S

P

E

H

N

N

N

R

V

T

T

R

R

F

F

V

V

M

V

I

L

G

S

K

K

E

N

P

K

T

Q

G

W

-

A

-

R

P

P

S

E

G

N

Y

D

D

E

Q

R

-

I

-

V

T

T

S

T

L

F

I

V

V

F

S

R

V

V

A

R

N
|
N

E
x
V

P

P

G

A

A

A

M
x
L

V

Y

K

K

L

A

L

L

E

G

P

G

L

F

A

A

R

T

H

N

G

G

V

V

S
x
N

M
|
M

T
|
T

R
x
K

F

L

E

E

S
|
S

R

Y

P

Q

A

L

R

G

V

G

G

R

T

F

W

I

E

A

Y
x
T

Y

Q

F
|
F

Y

Y

I

A

D

D

V

I

E

E

G

G

H

H

R

P

D

E

P

R

A

S

V

V

A

Q

A

L

A

A

L

L

A

E

G

E

L

L

G

R

E

F

K

F

A

T

A

K

F

E

L

V

K

R

I

I

L

L

G

G

S

V

Y

Y

binding phenylalanine: N207 (= N286), V208 (≠ E287), L212 (≠ M291), N225 (≠ S304), M226 (= M305), T227 (= T306), K228 (≠ R307), S231 (= S310), T241 (≠ Y320), F243 (= F322)

7am0B Gqqa- a novel type of quorum quenching acylases (see paper)
33% identity, 73% coverage: 95:356/359 of query aligns to 5:270/278 of 7am0B

query
sites
7am0B

A

A

Y

F

L

Q

G

G

P

R

V

P

G

G

T

A

Y

Y

S

S

E

D

Q

L

A

A

M

C

H

R

E

-

Y

-

F

-

G

-

Q

Q

S

A

I

R

E

P

G

G

-

W

-

T

L

L

P

P

C

C

P

Q

S

T

I

F

D

A

E

Q

V

T

F

I

R

A

S

A

V

V

E

H

A

D

G

G

A

R

A

A

D

E

Y

L

G

A

V

M

V

L

P

A

V

C

E

E

N

N

S

S

T

L

E

A

G

G

A

R

V

V

S

P

R

D

T

I

L

H

D

A

L

L

L

P

Q

E

T

A

Q

G

L

L

T

F

I

I

G

V

G

G

E

E

L

H

A

F

L

Q

P

R

I

V

H

E

H

H

N

C

L

L

T

G

Q

I

N

P

G

G

-

S

-

T

L

L

V

A

G

D

V

A

T

R

R

R

V

I

C

H

A

T

H

H

A

P

Q

V

A

A

L

M

A

A

Q

Q

C

V

Q

R

R

G

W

I

L

I

S

T

T

E

N

L

A

G

P

-

H

-

L

L

E

D

R

P

Q

V

A

V

V

E

S

F

S

D

N

T

A

A

E

G

A

A

R

E

M

M

A

V

S

R

E

E

-

W

-

G

D

R

P

K

T

E

V

D

A

V

A

A

I

V

A

A

G

S

D

A

R

L

A

A

I

E

H

L

Y

N

G

G

L

L

Q

E

V

I

T

L

N

R

A

R

L

N

I

V

Q

E

D

D

D

A

P

T

H

H

N

N

R

T

T

T

R

R

F

F

V

Y

M

I

I

A

G

S

K

R

E

R

P

P

T

A

G

T

-

L

-

P

P

P

S

G

G

P

Y

G

D

F

Q

M

T

T

S

T

L

L

I

L

V

F

S

R

V

V

A
x
N

N
|
N

E
x
Q

P
|
P

G

G

A

A

M
x
L

V

Y

K

K

L

A

L

L

E

G

P

G

L

L

A

A

R

T

H

A

G

G

V

V

S
x
N

M
|
M

T
|
T

R
|
R

F

L

E

E

S

S

R

Y

P

M

A

L

R

E

V

G

G

S

T

F

W

S

E

A

Y
x
T

Y

Q

F
|
F

Y

L

I

M

D

D

V

V

E

E

G

G

H

H

R

P

D

E

D

A

P

P

A

P

V

L

A

A

A

R

A

A

L

L

A

D

G

E

L

L

G

S

E

F

K

F

A

S

A

E

F

Q

L

Q

K

E

I

I

L

L

G

G

S

V

Y

Y

P

P

binding phenylalanine: N199 (≠ A285), N200 (= N286), Q201 (≠ E287), P202 (= P288), L205 (≠ M291), N218 (≠ S304), M219 (= M305), T220 (= T306), R221 (= R307), T234 (≠ Y320), F236 (= F322)

3luyA Putative chorismate mutase from bifidobacterium adolescentis
25% identity, 74% coverage: 93:357/359 of query aligns to 5:285/326 of 3luyA

query
sites
3luyA

K

K

A

L

A

F

Y

Y

L

L

G

G

P

P

V

Q

G

G

T

T

Y

F

S

T

E

H

Q

Q

A

A

-

A

-

V

-

N

-

A

-

Q

-

E

M

L

H

A

E

R

Y

F

F

E

G

P

Q

Q

S

G

I

F

E

D

G

L

L

M

P

P

C

M

P

D

S

D

I

V

D

P

E

Q

V

I

F

L

R

D

S

A

V

A

E

Q

A

H

G

G

A

D

A

G

D

-

Y

W

G

G

V

I

V

V

P

A

V

W

E

E

N

N

S

N

T

V

E

E

G

G

A

Y

V

V

S

V

R

P

T

N

L

L

D

D

L

A

L

L

L

I

Q

D

T

A

Q

K

L

D

T

L

I

V

G

G

-

F

G

A

E

R

L

V

A

G

L

V

P

N

I

V

H

E

H

F

N

D

-

A

L

Y

L

V

T

A

Q

Q

N

G

G

A

L

D

V

P

G

A

V

E

T

A

R

R

V

I

C

A

-

T

A

A

H

H

A

P

Q

H

A

G

L

L

A

A

Q

Q

C

C

Q

K

R

R

W

F

L

I

S

A

T

E

N

H

A

-

P

-

H

R

L

L

E

S

R

T

Q

Q

A

P

V

A

S

T

S

S

N

N

A

A

E

A

A

A

A

C

R

R

-

D

-

L

M

I

A

P

S

G

E

E

D

I

P

A

T

F

V

G

A

P

A

A

I

I

A

C

G

G

D

E

R

L

A

-

I

-

H

-

Y

Y

G

D

L

I

Q

T

V

R

T

I

N

G

A

T

L

A

I

I

Q

Q

D

D

D

Y

P

Q

H

G

N

A

R

A

T
|
T

R

D

F

F

V

L

M

V

I

L

G

S

K

P

-

R

-

A

-

E

-

V

-

A

-

R

-

L

-

A

E

K

P

P

T

R

G

A

P

E

S

A

G

N

-

V

-

E

Y

Y

D

E

Q

S

T

V

S

L

L

T

I

L

V

I

S

P

V

L

A

V

N

T

E
x
G

P

P

G

G

A

V

M
x
L

V

A

K

N

L

L

E

D

P

V

L

F

A

R

R

D

H

A

G

G

V

L

S

N

M

M

T

T

R

S

F

F

E

I

S

S

R

R

P

P

A

I

R

K

V

G

G

R

T

T

W

G

E

T

Y
|
Y

Y

S

F
|
F

Y

I

I

V

D

T

V

L

E

D

G

A

H

A

R

P

D

W

D

E

P

E

A

R

V

F

A

R

A

D

A

A

L

L

A

V

G

E

L

I

G

A

E

E

K

H

A

G

A

D

F

W

L

A

K

K

I

T

L

L

G

A

S

V

Y

Y

P

P

R

R

active site: T177 (= T260)
binding 3-phenylpyruvic acid: G215 (≠ E287), L219 (≠ M291), Y248 (= Y320), F250 (= F322)

7alzA Gqqa- a novel type of quorum quenching acylases (see paper)
36% identity, 38% coverage: 219:356/359 of query aligns to 46:186/194 of 7alzA

query
sites
7alzA

A

A

E

E

A

L

A

A

R

M

M

L

A

A

S

C

E

E

D

N

P

-

T

-

V

-

A

-

A

S

I

L

A

A

G

G

D

R

R

V

A

P

A

D

I

I

H

H

Y

A

-

L

-

P

-

E

-

A

G

G

L

L

Q

F

V

I

T

V

N

G

A

E

L

H

I

F

Q

Q

D

R

D

V

P

-

H

H

N

N

R

T

T

T

R

R

F

F

V

Y

M

I

I

A

G

S

K

R

E

R

P

P

T

A

G

T

-

L

-

P

P

P

S

G

G

P

Y

G

D

F

Q

M

T

T

S

T

L

L

I

L

V

F

S

R

V

V

A

N

N

N

E
x
Q

P

P

G

G

A

A

M
x
L

V

Y

K

K

L

A

L

L

E

G

P

G

L

L

A

A

R

T

H

A

G

G

V

V

S
x
N

M
|
M

T
|
T

R
|
R

F

L

E

E

S

S

R

Y

P

M

A

L

R

E

V

G

G

S

T

F

W

S

E

A

Y
x
T

Y

Q

F
|
F

Y

L

I

M

D

D

V

V

E

E

G

G

H

H

R

P

D

E

D

A

P

P

A

P

V

L

A

A

A

R

A

A

L

L

A

D

G

E

L

L

G

S

E

F

K

F

A

S

A

E

F

Q

L

Q

K

E

I

I

L

L

G

G

S

V

Y

Y

P

P

binding phenylalanine: Q117 (≠ E287), L121 (≠ M291), N134 (≠ S304), M135 (= M305), T136 (= T306), R137 (= R307), T150 (≠ Y320), F152 (= F322)

5j6fA Crystal structure of dah7ps-cm complex from geobacillus sp. With prephenate (see paper)
29% identity, 31% coverage: 6:116/359 of query aligns to 1:112/352 of 5j6fA

query
sites
5j6fA

N

N

T

E

R

R

L

L

K

D

P

E

L

L

R

R

D

A

R

R

I

V

D

D

A

E

L

I

D

N

A

L

Q

Q

L

L

I

L

A

K

L

L

L

I

N

N

Q

E

R
|
R

A

G

S

R

V

L

A

V

L

Q

E

E

V
x
I

G

G

E

K

V

I

K
|
K

K

E

H

A

F

Q

N

G

A

T

P

H

V

R

F
x
Y

R
x
D

P

P

E

V

R
|
R

E

E

M

R

Q

K

V
x
M

I

L

A

D

R

L

L

I

Q

S

E

E

M

H

S

N

A

D

G

G

P

P

L

F

A

E

D

T

E

S

H

T

I

L

S

Q

A

H

I

I

W

F

R

K

E

E

I

I

M

F

A

K

A

A

S

A

R

L

A

E

L

L

-

Q

E

E

R

D

S

D

I

H

K

R

A

K

A

A

Y

L

L

L

G

V

P

S

V

R

G

K

T

K

Y

H

S

P

E

E

Q

N

A

T

M

I

H

V

E

E

Y

V

F

K

G

G

Q

E

S

R

I

I

binding prephenic acid: R25 (= R30), I32 (≠ V37), K36 (= K41), Y44 (≠ F49), D45 (≠ R50), R48 (= R53), M52 (≠ V57)

Sites not aligning to the query:

binding manganese (ii) ion: 124, 294, 320, 331

P39912 Protein AroA(G); EC 2.5.1.54; EC 5.4.99.5 from Bacillus subtilis (strain 168) (see paper)
33% identity, 23% coverage: 6:89/359 of query aligns to 3:86/358 of P39912

query
sites
P39912

N

N

T

T

R

E

L

L

K

E

P

L

L

L

R

R

D

Q

R

K

I

A

D

D

A

E

L

L

D

N

A

L

Q

Q

L

I

I

L

A

K

L

L

L

I

N

N

Q

E

R

R

A

G

S

N

V

V

A

V

L

K

E

E

V

I

G

G

E

K

V

A

K

K

K

E

H

A

F

Q

N

G

A

V

P

N

V

R

F

F

R

D

P

P

E

V

R

R

E

E

M

R

Q

T

V

M

I

L

A

N

R

N

L

I

Q

I

E

E

M

N

S

N

A

D

G

G

P

P

L

F

A

E

D

N

E

S

H

T

I

I

S

Q

A

H

I

I

W

F

R

K

E

E

I

I

M

F

A

K

A

A

S

G

R

L

A

E

L

L

E

Q

Sites not aligning to the query:

2 modified: Phosphoserine

5gmuB Crystal structure of chorismate mutase like domain of bifunctional dahp synthase of bacillus subtilis in complex with chlorogenic acid (see paper)
33% identity, 23% coverage: 6:89/359 of query aligns to 2:85/87 of 5gmuB

query
sites
5gmuB

N

N

T

T

R

E

L

L

K

E

P

L

L

L

R

R

D

Q

R

K

I

A

D

D

A

E

L

L

D

N

A

L

Q

Q

L

I

I

L

A

K

L

L

L

I

N

N

Q

E

R
|
R

A

G

S

N

V

V

A

V

L

K

E

E

V

I

G

G

E

K

V

A

K

K

K

E

H

A

F

Q

N

G

A

V

P

N

V
x
R

F
|
F

R
x
D

P

P

E

V

R

R

E
|
E

M

R

Q

T

V

M

I

L

A

N

R

N

L

I

Q

I

E

E

M

N

S

N

A

D

G

G

P

P

L

F

A

E

D

N

E

S

H

T

I

I

S

Q

A

H

I

I

W

F

R

K

E

E

I

I

M
x
F

A
x
K

A

A

S

G

R
x
L

A

E

L

L

E
x
Q

binding (1R,3R,4S,5R)-3-[3-[3,4-bis(oxidanyl)phenyl]propanoyloxy]-1,4,5-tris(oxidanyl)cyclohexane-1-carboxylic acid: R26 (= R30), R44 (≠ V48), F45 (= F49), D46 (≠ R50), E50 (= E54), F78 (≠ M82), K79 (≠ A83), L82 (≠ R86), Q85 (≠ E89)

6al9B Crystal structure of chorismate mutase from helicobacter pylori in complex with prephenate
31% identity, 24% coverage: 5:91/359 of query aligns to 1:85/91 of 6al9B

query
sites
6al9B

L

L

N

D

T

S

R

L

L

L

K

E

P

N

L

L

R

R

D

A

R

E

I

I

D

D

A

A

L

L

D

D

A

N

Q

E

L

L

I

S

A

D

L

L

N

D

Q

K

R

R

A

L

S

E

V

I

A

A

L

L

E

K

V
x
I

G

A

E

L

V

I

K

K

K

Q

H

E

F

-

N

-

A

S

P

P

V

I

F

Y

R

C

P

P

E

K

R

R

E

E

M

Q

Q

E

V

I

I

L

A

K

R

R

L

L

Q

S

E

Q

M

R

S

D

A

F

G

K

P

H

L

L

A

N

D

G

E

E

H

I

I

L

S

T

A

G

I

F

W

Y

R

T

E

E

I

V

M

F

A

K

A

I

S

S

R

R

A

K

L

F

E
x
Q

R

E

S

N

binding pyruvic acid: I33 (≠ V37), Q83 (≠ E89)

6al9A Crystal structure of chorismate mutase from helicobacter pylori in complex with prephenate
30% identity, 24% coverage: 6:91/359 of query aligns to 1:84/90 of 6al9A

query
sites
6al9A

N

D

T

S

R

L

L

L

K

E

P

N

L

L

R

R

D

A

R

E

I

I

D

D

A

A

L

L

D

D

A

N

Q

E

L

L

I

S

A

D

L

L

N

D

Q

K

R
|
R

A

L

S

E

V

I

A

A

L

L

E

K

V

I

G

A

E

L

V

I

K

K

K

Q

H

E

F

-

N

-

A

S

P

P

V

I

F

Y

R
x
C

P

P

E

K

R
|
R

E
|
E

M

Q

Q

E

V

I

I

L

A

K

R

R

L

L

Q

S

E

Q

M

R

S

D

A

F

G

K

P

H

L

L

A

N

D

G

E

E

H

I

I

L

S

T

A

G

I

F

W

Y

R

T

E

E

I

V

M
x
F

A

K

A

I

S
|
S

R

R

A

K

L

F

E
x
Q

R

E

S

N

binding prephenic acid: R25 (= R30), C43 (≠ R50), R46 (= R53), E47 (= E54), F75 (≠ M82), S78 (= S85), Q82 (≠ E89)

3nvtA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e (see paper)
26% identity, 33% coverage: 12:128/359 of query aligns to 2:109/345 of 3nvtA

query
sites
3nvtA

L

L

R

R

D

T

R

Q

I

V

D

D

A

Q

L

L

D

N

A

I

Q

D

L

L

I

L

A

E

L

L

L

I

N

S

Q

K

R

R

A

A

S

N

V

L

A

V

L

Q

E

E

V

I

G

G

E

K

V

I

K

K

K

G

H

R

F

F

N

D

A

-

P

-

V

-

F

-

R

-

P

P

E

L

R

R

E

E

M

R

Q

E

V

M

I

L

A

N

R

T

L

I

Q

L

E

A

M

A

S

N

A

E

G

G

P

P

L

F

A

E

D

D

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I

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S

Q

A

K

I

L

W

F

R

K

E

E

I

I

M

F

A

K

A

A

S

G

R

L

A

E

L

L

E

Q

R

E

S

E

I

D

K

H

A

S

A

K

Y

A

L

L

G

-

P

-

V

-

G

-

T

L

Y

V

S

S

E

R

Q

K

A

N

M

K

H

K

E

E

Y

D

F

T

G

I

Q

V

S

T

I

V

E

K

G

G

L

L

P

P

C

I

P

G

S

N

I

G

D

E

E

P

V

V

F

F

Sites not aligning to the query:

binding manganese (ii) ion: 114, 284, 310, 321

3tfcA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e in complex with phosphoenolpyruvate (see paper)
26% identity, 33% coverage: 12:128/359 of query aligns to 1:108/343 of 3tfcA

query
sites
3tfcA

L

L

R

R

D

T

R

Q

I

V

D

D

A

Q

L

L

D

N

A

I

Q

D

L

L

I

L

A

E

L

L

L

I

N

S

Q

K

R

R

A

A

S

N

V

L

A

V

L

Q

E

E

V

I

G

G

E

K

V

I

K

K

K

L

H

R

F

F

N

D

A

-

P

-

V

-

F

-

R

-

P

P

E

L

R

R

E

E

M

R

Q

E

V

M

I

L

A

N

R

T

L

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E

A

M

A

S

N

A

E

G

G

P

P

L

F

A

E

D

D

E

S

H

T

I

V

S

Q

A

K

I

L

W

F

R

K

E

E

I

I

M

F

A

K

A

A

S

G

R

L

A

E

L

L

E

Q

R

E

S

E

I

D

K

H

A

S

A

K

Y

A

L

L

G

-

P

-

V

-

G

-

T

L

Y

V

S

S

E

R

Q

K

A

N

M

K

H

K

E

E

Y

D

F

T

G

I

Q

V

S

T

I

V

E

K

G

G

L

L

P

P

C

I

P

G

S

N

I

G

D

E

E

P

V

V

F

F

Sites not aligning to the query:

binding manganese (ii) ion: 113, 283, 309, 320
binding phosphoenolpyruvate: 137, 193, 196, 218, 248, 283

1ecmB Atomic structure of the buried catalytic pocket of escherichia coli chorismate mutase
31% identity, 26% coverage: 9:101/359 of query aligns to 2:95/95 of 1ecmB

query
sites
1ecmB

L

L

K

L

P

A

L

L

R

R

D

E

R

K

I

I

D

S

A

A

L

L

D

D

A

E

Q

K

L

L

I

L

A

A

L

L

N

A

Q

E

R
|
R

A

R

S

E

V

L

A

A

L

V

E

E

V
|
V

G

G

E

K

V

A

K
|
K

K

L

H

L

F

S

N

H

A

R

P

P

V

V

F
x
R

R
x
D

P

I

E

D

R
|
R

E
|
E

M

R

Q

D

V

L

I

L

A

E

R

R

L

L

Q

I

E

T

M

L

S

G

A

K

G

A

P

H

L

H

A

L

D

D

E

A

H

H

-

Y

I

I

S

T

A

R

I

L

W

F

R

Q

E

L

I

I

M
x
I

A

E

A

D

S
|
S

R

V

A

L

L

T

E
x
Q

R

Q

S

A

I

L

K

L

A

Q

Y

H

L

L

G

N

P

K

V

I

G

N

binding 8-hydroxy-2-oxa-bicyclo[3.3.1]non-6-ene-3,5-dicarboxylic acid: R23 (= R30), V30 (= V37), K34 (= K41), R42 (≠ F49), D43 (≠ R50), R46 (= R53), E47 (= E54), I76 (≠ M82), S79 (= S85), Q83 (≠ E89)

Query Sequence

>WP_013090145.1 NCBI__GCF_000092885.1:WP_013090145.1
MDDELNTRLKPLRDRIDALDAQLIALLNQRASVALEVGEVKKHFNAPVFRPEREMQVIAR
LQEMSAGPLADEHISAIWREIMAASRALERSIKAAYLGPVGTYSEQAMHEYFGQSIEGLP
CPSIDEVFRSVEAGAADYGVVPVENSTEGAVSRTLDLLLQTQLTIGGELALPIHHNLLTQ
NGLVGVTRVCAHAQALAQCQRWLSTNAPHLERQAVSSNAEAARMASEDPTVAAIAGDRAA
IHYGLQVTNALIQDDPHNRTRFVMIGKEPTGPSGYDQTSLIVSVANEPGAMVKLLEPLAR
HGVSMTRFESRPARVGTWEYYFYIDVEGHRDDPAVAAALAGLGEKAAFLKILGSYPRAR

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory