SitesBLAST
Comparing WP_013094330.1 NCBI__GCF_000092885.1:WP_013094330.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
3tatA Tyrosine aminotransferase from e. Coli (see paper)
58% identity, 99% coverage: 1:396/401 of query aligns to 1:397/397 of 3tatA
- active site: W131 (= W130), D212 (= D211), A214 (= A213), K247 (= K246)
- binding pyridoxal-5'-phosphate: G103 (= G102), G104 (= G103), S105 (= S104), H179 (= H178), N184 (= N183), A214 (= A213), S246 (= S245), K247 (= K246), R255 (= R254)
3fslA Crystal structure of tyrosine aminotransferase tripple mutant (p181q, r183g,a321k) from escherichia coli at 2.35 a resolution
58% identity, 99% coverage: 1:396/401 of query aligns to 1:397/397 of 3fslA
- active site: W131 (= W130), D212 (= D211), A214 (= A213), K247 (= K246)
- binding (5-hydroxy-4,6-dimethylpyridin-3-yl)methyl dihydrogen phosphate: G103 (= G102), G104 (= G103), S105 (= S104), W131 (= W130), N184 (= N183), D212 (= D211), A214 (= A213), Y215 (= Y214), S244 (= S243), S246 (= S245), K247 (= K246), R255 (= R254)
6zvgA Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with substrate analog - l-indole-3-lactic acid (see paper)
50% identity, 99% coverage: 1:396/401 of query aligns to 1:396/398 of 6zvgA
- binding 3-(indol-3-yl) lactate: D11 (= D11), I13 (= I13), L14 (= L14), I33 (= I33), G34 (= G34), W130 (= W130), K246 (= K246), R374 (= R374)
- binding pyridoxal-5'-phosphate: G102 (= G102), G103 (= G103), S104 (= S104), W130 (= W130), N183 (= N183), D211 (= D211), Y214 (= Y214), S243 (= S243), S245 (= S245), K246 (= K246), R254 (= R254)
6zurA Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with substrate analog - l-p-hydroxyphenyllactic acid (see paper)
50% identity, 99% coverage: 1:396/401 of query aligns to 1:396/398 of 6zurA
- binding pyridoxal-5'-phosphate: G102 (= G102), G103 (= G103), S104 (= S104), W130 (= W130), D211 (= D211), A213 (= A213), Y214 (= Y214), S243 (= S243), S245 (= S245), K246 (= K246), R254 (= R254)
- binding (2S)-2-hydroxy-3-(4-hydroxyphenyl)propanoic acid: G34 (= G34), W130 (= W130), R374 (= R374)
6zupA Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with substrate analog - l-(-)-3-phenyllactic acid (see paper)
50% identity, 99% coverage: 1:396/401 of query aligns to 1:396/398 of 6zupA
- binding alpha-hydroxy-beta-phenyl-propionic acid: I13 (= I13), I33 (= I33), G34 (= G34), W130 (= W130), K246 (= K246), R374 (= R374)
- binding pyridoxal-5'-phosphate: G102 (= G102), G103 (= G103), S104 (= S104), W130 (= W130), N183 (= N183), D211 (= D211), A213 (= A213), Y214 (= Y214), S243 (= S243), S245 (= S245), K246 (= K246), R254 (= R254)
4rkdC Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with aspartic acid (see paper)
50% identity, 99% coverage: 1:396/401 of query aligns to 1:396/398 of 4rkdC
- active site: W130 (= W130), D211 (= D211), A213 (= A213), K246 (= K246)
- binding oxaloacetate ion: Y65 (= Y65), R280 (= R280)
- binding pyridoxal-5'-phosphate: G102 (= G102), G103 (= G103), S104 (= S104), W130 (= W130), N183 (= N183), D211 (= D211), Y214 (= Y214), S243 (= S243), S245 (= S245), K246 (= K246), R254 (= R254)
4rkdA Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with aspartic acid (see paper)
50% identity, 99% coverage: 1:396/401 of query aligns to 1:396/398 of 4rkdA
- active site: W130 (= W130), D211 (= D211), A213 (= A213), K246 (= K246)
- binding 2-[(3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethylene)-amino]-succinic acid: G34 (= G34), G102 (= G102), G103 (= G103), S104 (= S104), W130 (= W130), D211 (= D211), S243 (= S243), S245 (= S245), K246 (= K246), R254 (= R254)
- binding pyridoxal-5'-phosphate: G102 (= G102), G103 (= G103), S104 (= S104), W130 (= W130), D211 (= D211), A213 (= A213), Y214 (= Y214), S243 (= S243), S245 (= S245), K246 (= K246), R254 (= R254)
4rkcA Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 (see paper)
50% identity, 99% coverage: 1:396/401 of query aligns to 1:396/398 of 4rkcA
- active site: W130 (= W130), D211 (= D211), A213 (= A213), K246 (= K246)
- binding 4'-deoxy-4'-aminopyridoxal-5'-phosphate: G102 (= G102), G103 (= G103), S104 (= S104), W130 (= W130), D211 (= D211), A213 (= A213), Y214 (= Y214), S243 (= S243), S245 (= S245), K246 (= K246), R254 (= R254)
P12344 Aspartate aminotransferase, mitochondrial; mAspAT; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A; EC 2.6.1.1 from Bos taurus (Bovine) (see 2 papers)
42% identity, 98% coverage: 4:395/401 of query aligns to 35:428/430 of P12344
- K309 (≠ T276) modified: N6-succinyllysine; alternate
Sites not aligning to the query:
- 1:29 modified: transit peptide, Mitochondrion
1ahxA Aspartate aminotransferase hexamutant (see paper)
42% identity, 99% coverage: 1:396/401 of query aligns to 1:396/396 of 1ahxA
- active site: W130 (= W130), D211 (= D211), A213 (= A213), K246 (= K246)
- binding hydrocinnamic acid: I13 (= I13), L14 (= L14), G34 (= G34), W130 (= W130), K246 (= K246), R374 (= R374)
- binding pyridoxal-5'-phosphate: G102 (= G102), G103 (= G103), S104 (= S104), W130 (= W130), N183 (= N183), D211 (= D211), A213 (= A213), Y214 (= Y214), S243 (= S243), S245 (= S245), K246 (= K246), R254 (= R254)
1ahgA Aspartate aminotransferase hexamutant (see paper)
42% identity, 99% coverage: 1:396/401 of query aligns to 1:396/396 of 1ahgA
- active site: W130 (= W130), D211 (= D211), A213 (= A213), K246 (= K246)
- binding pyridoxal-5'-phosphate: G103 (= G103), S104 (= S104), W130 (= W130), N183 (= N183), D211 (= D211), S243 (= S243), S245 (= S245), R254 (= R254)
- binding tyrosine: D11 (= D11), I13 (= I13), L14 (= L14), W130 (= W130), R374 (= R374)
1ahfA Aspartate aminotransferase hexamutant (see paper)
42% identity, 99% coverage: 1:396/401 of query aligns to 1:396/396 of 1ahfA