SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_013419178.1 NCBI__GCF_000166055.1:WP_013419178.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

Q8DNZ8 Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit GatD; Lipid II isoglutaminyl synthase glutaminase subunit; EC 6.3.5.13; EC 3.5.1.2 from Streptococcus pneumoniae (strain ATCC BAA-255 / R6) (see paper)
27% identity, 32% coverage: 280:438/491 of query aligns to 52:207/260 of Q8DNZ8

query
sites
Q8DNZ8
V
 
V
D
 
D
L
 
I
V
 
V
A
 
S
L
 
L
A
 
-
H
 
H
G
 
D
E
 
D
P
 
F
L
 
D
P
 
E
A
 
N
D
 
H
A
 
Y
D
 
D
L
 
I
V
 
A
I
 
F
L
 
F
P
 
G
G
 
G
S
 
G
K
 
Q
A
 
D
T
 
F
I
 
E
A
 
Q
D
 
S
L
 
I
T
 
I
A
 
A
L
 
D
R
 
D
A
 
L
C
 
P
G
 
A
W
 
K
E
 
K
A
 
E
D
 
S
I
 
I
V
 
D
A
 
N
H
 
Y
V
 
I
R
 
Q
R
 
N
G
 
D
G
 
G
R
 
V
V
 
V
L
 
L
G
 
A
L
 
I
C
 
C
G
 
G
G
 
G
Y
 
F
Q
 
Q
M
 
L
L
 
L
G
 
G
R
 
Q
W
 
Y
V
 
Y
A
 
V
D
 
E
P
 
A
A
 
S
G
 
G
V
 
K
E
 
R
G
 
-
R
 
-
P
 
-
G
 
-
G
 
-
V
 
I
P
 
E
G
 
G
L
 
L
G
 
G
L
 
V
L
 
M
D
 
-
V
 
-
E
 
-
T
 
-
E
 
-
L
 
-
A
 
-
G
 
G
D
 
H
K
 
Y
T
 
T
L
 
L
A
 
N
A
 
Q
V
 
T
T
 
N
G
 
N
R
|
R
T
 
F
A
 
I
A
 
G
D
 
D
-
 
I
-
 
K
-
 
I
-
 
H
-
 
N
-
 
E
-
 
D
-
 
F
N
 
D
V
 
E
P
 
T
L
 
Y
S
 
Y
G
 
G
Y
 
F
E
 
E
I
 
N
H
 
H
I
 
Q
G
 
G
R
 
R
T
 
T
F
 
F
G
 
L
S
 
S
D
 
D
T
 
D
A
 
Q
R
 
K
P
 
P
L
 
L
-
 
G
V
 
Q
L
 
V
L
 
V
H
 
Y
E
 
G
D
 
N
G
 
G
G
 
N
C
 
N
R
 
E
P
 
E
D
 
K
-
 
V
G
 
G
A
 
E
V
 
G
S
 
V
A
 
H
D
 
Y
G
 
K
R
 
N
V
 
V
M
 
F
G
 
G
S
 
S
Y
 
Y
V
 
F
H
 
H
G
 
G

6fqbE Murt/gatd peptidoglycan amidotransferase complex from streptococcus pneumoniae r6 (see paper)
27% identity, 32% coverage: 280:438/491 of query aligns to 52:207/247 of 6fqbE

query
sites
6fqbE
V
 
V
D
 
D
L
 
I
V
 
V
A
 
S
L
 
L
A
 
-
H
 
H
G
 
D
E
 
D
P
 
F
L
 
D
P
 
E
A
 
N
D
 
H
A
 
Y
D
 
D
L
 
I
V
 
A
I
 
F
L
 
F
P
 
G
G
 
G
S
 
G
K
 
Q
A
 
D
T
 
F
I
 
E
A
 
Q
D
 
S
L
 
I
T
 
I
A
 
A
L
 
D
R
 
D
A
 
L
C
 
P
G
 
A
W
 
K
E
 
K
A
 
E
D
 
S
I
 
I
V
 
D
A
 
N
H
 
Y
V
 
I
R
 
Q
R
 
N
G
 
D
G
 
G
R
 
V
V
 
V
L
 
L
G
 
A
L
 
I
C
|
C
G
 
G
G
 
G
Y
 
F
Q
|
Q
M
 
L
L
 
L
G
 
G
R
 
Q
W
 
Y
V
 
Y
A
 
V
D
 
E
P
 
A
A
 
S
G
 
G
V
 
K
E
 
R
G
 
-
R
 
-
P
 
-
G
 
-
G
 
-
V
 
I
P
 
E
G
 
G
L
 
L
G
 
G
L
 
V
L
 
M
D
 
-
V
 
-
E
 
-
T
 
-
E
 
-
L
 
-
A
 
-
G
 
G
D
 
H
K
 
Y
T
 
T
L
 
L
A
 
N
A
 
Q
V
 
T
T
 
N
G
 
N
R
 
R
T
 
F
A
 
I
A
 
G
D
 
D
-
 
I
-
 
K
-
 
I
-
 
H
-
 
N
-
 
E
-
 
D
-
 
F
N
 
D
V
 
E
P
 
T
L
 
Y
S
 
Y
G
 
G
Y
 
F
E
 
E
I
x
N
H
 
H
I
x
Q
G
|
G
R
 
R
T
 
T
F
 
F
G
 
L
S
 
S
D
 
D
T
 
D
A
 
Q
R
 
K
P
 
P
L
 
L
-
 
G
V
 
Q
L
 
V
L
 
V
H
 
Y
E
 
G
D
 
N
G
 
G
G
 
N
C
 
N
R
 
E
P
 
E
D
 
K
-
 
V
G
 
G
A
 
E
V
 
G
S
 
V
A
 
H
D
 
Y
G
 
K
R
 
N
V
 
V
M
 
F
G
 
G
S
 
S
Y
 
Y
V
 
F
H
|
H
G
 
G

Query Sequence

>WP_013419178.1 NCBI__GCF_000166055.1:WP_013419178.1
MTARALMFQGTGSDVGKSLIVAGMCRLLADRGLSVRPFKPQNMSTNAGVTADGGEIGRAQ
MLQARAARVAPSVHMNPVLLKPQSDTGAQIVVQGKVWGRAEARDYQSRKAALMPPVLESF
ARLKAECDLVLIEGAGSPSEVNLRANDIANMGFARAADVPVVLIGDIDRGGVIASLVGTK
AVLDAEDAAMIRGFIVNKMRGDASLFADGMRFVADRTGWTPLGLVPWFADAHALPPEDGF
SRDWVREGAKAGQRVKIAVPVLPHIANFDDLDPLRLEPGVDLVALAHGEPLPADADLVIL
PGSKATIADLTALRACGWEADIVAHVRRGGRVLGLCGGYQMLGRWVADPAGVEGRPGGVP
GLGLLDVETELAGDKTLAAVTGRTAADNVPLSGYEIHIGRTFGSDTARPLVLLHEDGGCR
PDGAVSADGRVMGSYVHGLFAEDRQRAAWLARLGGEPSALSYEAAIDDTLDRLAAHLARH
LDIEALLALAC

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory