SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_013419231.1 NCBI__GCF_000166055.1:WP_013419231.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

Q51507 Isochorismate pyruvate lyase; IPL; Chorismate mutase; CM; Salicylate biosynthesis protein; EC 4.2.99.21; EC 5.4.99.5 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 5 papers)
29% identity, 86% coverage: 1:90/105 of query aligns to 1:87/101 of Q51507

query
sites
Q51507
M
 
M
T
 
K
T
 
T
P
 
P
R
 
E
K
 
-
A
 
-
A
 
-
D
 
D
C
 
C
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T
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G
M
 
L
D
 
A
Q
 
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V
 
I
R
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E
E
 
A
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I
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D
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R
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I
D
 
D
D
 
L
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D
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I
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V
D
 
Q
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A
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L
A
 
G
E
 
R
R
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R
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M
S
 
D
Y
 
Y
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V
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K
R
x
A
A
 
A
W
 
S
Q
 
R
L
 
F
K
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K
K
x
A
N
 
S
T
 
E
H
 
A
E
 
A
A
 
I
T
 
P
V
 
A
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P
W
 
E
R
 
R
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A
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A
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M
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R
 
E
V
 
R
E
 
A
A
 
R
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W
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A
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E
E
 
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R
 
N
D
 
G
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L
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D
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A
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P
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V
 
E
A
 
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F
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A
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Q
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I
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I
G
 
H
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W
F
 
Y
I
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I

Sites not aligning to the query:

2h9dD Pyruvate-bound structure of the isochorismate-pyruvate lyase from pseudomonas aerugionsa (see paper)
29% identity, 86% coverage: 1:90/105 of query aligns to 1:87/100 of 2h9dD

query
sites
2h9dD
M
 
M
T
 
K
T
 
T
P
 
P
R
 
E
K
 
-
A
 
-
A
 
-
D
 
D
C
 
C
E
 
T
N
 
G
M
 
L
D
 
A
Q
 
D
V
 
I
R
 
R
V
x
E
E
 
A
I
 
I
D
|
D
R
 
R
V
 
I
D
 
D
D
 
L
A
 
D
I
 
I
L
 
V
D
 
Q
L
 
A
V
 
L
A
 
G
E
 
R
R
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R
F
 
M
S
 
D
Y
 
Y
V
 
V
D
 
K
R
 
A
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A
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L
 
F
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K
K
 
A
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S
T
 
E
H
 
A
E
 
A
A
 
I
T
 
P
V
 
A
P
 
P
W
 
E
R
 
R
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V
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A
Q
 
A
V
x
M
I
 
L
D
 
P
R
 
E
V
 
R
E
 
A
A
 
R
R
 
W
A
 
A
K
 
E
E
 
E
R
 
N
D
 
G
L
 
L
P
 
D
P
 
A
E
 
P
L
 
F
A
 
V
V
 
E
A
 
G
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L
W
 
F
R
 
A
Q
 
Q
M
 
I
I
 
I
G
 
H
W
 
W
F
 
Y
I
 
I

Sites not aligning to the query:

Query Sequence

>WP_013419231.1 NCBI__GCF_000166055.1:WP_013419231.1
MTTPRKAADCENMDQVRVEIDRVDDAILDLVAERFSYVDRAWQLKKNTHEATVPWRIRQV
IDRVEARAKERDLPPELAVALWRQMIGWFIQYEEEKLAKRGEPKD

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory