Comparing WP_013421135.1 NCBI__GCF_000166055.1:WP_013421135.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4lmaA Crystal structure analysis of o-acetylserine sulfhydrylase cysk1 from microcystis aeruginosa 7806 (see paper)
56% identity, 93% coverage: 18:326/332 of query aligns to 2:310/318 of 4lmaA
2q3dA 2.2 a resolution crystal structure of o-acetylserine sulfhydrylase (oass) from mycobacterium tuberculosis in complex with the reaction intermediate alpha-aminoacrylate (see paper)
56% identity, 92% coverage: 19:324/332 of query aligns to 3:305/306 of 2q3dA
P9WP55 O-acetylserine sulfhydrylase; OAS sulfhydrylase; OASS; Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine-specific cysteine synthase; Sulfide-dependent cysteine synthase; EC 2.5.1.47 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
56% identity, 92% coverage: 19:324/332 of query aligns to 3:305/310 of P9WP55
4lmbA Crystal structure analysis of o-acetylserine sulfhydrylase cysk2 complexed with cystine from microcystis aeruginosa 7806 (see paper)
55% identity, 93% coverage: 19:326/332 of query aligns to 3:310/310 of 4lmbA
4aecA Crystal structure of the arabidopsis thaliana o-acetyl-serine-(thiol)- lyasE C (see paper)
55% identity, 93% coverage: 18:326/332 of query aligns to 12:318/323 of 4aecA
5xoqA Crystal structure of o-acetylserine sulfhydrylase with bound transcription factor peptide inhibitor from planctomyces limnophilus
55% identity, 93% coverage: 19:326/332 of query aligns to 4:308/310 of 5xoqA
3zeiA Structure of the mycobacterium tuberculosis o-acetylserine sulfhydrylase (oass) cysk1 in complex with a small molecule inhibitor (see paper)
55% identity, 91% coverage: 19:319/332 of query aligns to 3:300/300 of 3zeiA
2q3cA 2.1 a resolution crystal structure of o-acetylserine sulfhydrylase (oass) holoenzyme from mycobacterium tuberculosis in complex with the inhibitory peptide dfsi (see paper)
55% identity, 91% coverage: 19:319/332 of query aligns to 3:300/300 of 2q3cA
7n2tA O-acetylserine sulfhydrylase from citrullus vulgaris in the internal aldimine state, with citrate bound (see paper)
55% identity, 93% coverage: 19:326/332 of query aligns to 3:308/309 of 7n2tA
P47999 Cysteine synthase, chloroplastic/chromoplastic; At.OAS.7-4; Beta-substituted Ala synthase 2;1; ARAth-Bsas2;1; CSase B; AtCS-B; CS-B; O-acetylserine (thiol)-lyase; O-acetylserine sulfhydrylase; OAS-TL B; cpACS1; EC 2.5.1.47 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
54% identity, 90% coverage: 27:326/332 of query aligns to 83:380/392 of P47999
Sites not aligning to the query:
P47998 Cysteine synthase 1; At.OAS.5-8; Beta-substituted Ala synthase 1;1; ARAth-Bsas1;1; CSase A; AtCS-A; Cys-3A; O-acetylserine (thiol)-lyase 1; OAS-TL A; O-acetylserine sulfhydrylase; Protein ONSET OF LEAF DEATH 3; EC 2.5.1.47 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
53% identity, 94% coverage: 18:329/332 of query aligns to 4:313/322 of P47998
2isqA Crystal structure of o-acetylserine sulfhydrylase from arabidopsis thaliana in complex with c-terminal peptide from arabidopsis serine acetyltransferase (see paper)
53% identity, 94% coverage: 18:329/332 of query aligns to 2:311/320 of 2isqA
1z7yA Crystal structure of the arabidopsis thaliana o-acetylserine sulfhydrylase k46a mutant (see paper)
53% identity, 94% coverage: 18:329/332 of query aligns to 2:311/320 of 1z7yA
8b9wA Cysteine synthase from trypanosoma theileri with plp bound (see paper)
52% identity, 90% coverage: 27:326/332 of query aligns to 17:313/329 of 8b9wA
Q93244 Cysteine synthase 1; O-acetylserine (thiol)-lyase 1; OAS-TL; EC 2.5.1.47 from Caenorhabditis elegans (see 2 papers)
51% identity, 93% coverage: 16:324/332 of query aligns to 4:310/341 of Q93244
3t4pA Crystal structure of o-acetyl serine sulfhydrylase from leishmania donovani in complex with designed tetrapeptide (see paper)
49% identity, 93% coverage: 18:326/332 of query aligns to 9:314/319 of 3t4pA
8b9yC Cysteine synthase from trypanosoma cruzi with plp and oas (see paper)
49% identity, 94% coverage: 16:326/332 of query aligns to 7:314/330 of 8b9yC
3bm5A Crystal structure of o-acetyl-serine sulfhydrylase from entamoeba histolytica in complex with cysteine (see paper)
45% identity, 93% coverage: 16:325/332 of query aligns to 9:319/338 of 3bm5A
4jbnA Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with serine acetyl transferase derived tetrapeptide, spsi (see paper)
45% identity, 93% coverage: 16:325/332 of query aligns to 9:319/336 of 4jbnA
4il5A Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with isoleucine (see paper)
45% identity, 93% coverage: 16:325/332 of query aligns to 9:319/336 of 4il5A
>WP_013421135.1 NCBI__GCF_000166055.1:WP_013421135.1
MQRRARKRPAQTRWGRGHIYKDITGAIGNTPLVQINAMAEAANAHATLLAKLEFMNPLAS
VKDRIALAMIEAAEAEGRIVPGESVLIEPTSGNTGIALAFVAAVKRYRLIVVAPESMSVE
RRKMLSHLGAEIQLTPAALGMTGALSQADALAARLPEAVILQQFSNPANPTIHAMTTAEE
IWADTDGAVDVVVAGVGTGGTLTGCARVLRPRKQGLQVIAVEPEASSVLSGGSSGSHGLQ
GIGPGFIPAVLDQSLIDEVLTISNETAYETARQAAKLEGLPIGISSGAALAAGLKIAARP
RLRGKTVVVIIPSSAERELSTPLFESTSRIND
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory