Comparing WP_013451358.1 NCBI__GCF_000183405.1:WP_013451358.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 10 hits to proteins with known functional sites (download)
4f4fA X-ray crystal structure of plp bound threonine synthase from brucella melitensis
43% identity, 99% coverage: 1:461/464 of query aligns to 2:460/464 of 4f4fA
Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
47% identity, 92% coverage: 1:425/464 of query aligns to 5:463/514 of Q42598
1kl7A Crystal structure of threonine synthase from yeast (see paper)
47% identity, 91% coverage: 3:425/464 of query aligns to 7:460/509 of 1kl7A
8g1yA Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
38% identity, 94% coverage: 3:440/464 of query aligns to 7:460/496 of 8g1yA
1vb3A Crystal structure of threonine synthase from escherichia coli
33% identity, 95% coverage: 1:442/464 of query aligns to 1:407/428 of 1vb3A
2c2bA Crystallographic structure of arabidopsis thaliana threonine synthase complexed with pyridoxal phosphate and s-adenosylmethionine (see paper)
22% identity, 69% coverage: 96:417/464 of query aligns to 113:403/444 of 2c2bA
Sites not aligning to the query:
Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
22% identity, 69% coverage: 96:417/464 of query aligns to 188:478/526 of Q9S7B5
Sites not aligning to the query:
2c2gA Crystal structure of threonine synthase from arabidopsis thaliana in complex with its cofactor pyridoxal phosphate (see paper)
24% identity, 41% coverage: 96:285/464 of query aligns to 131:312/448 of 2c2gA
6cgqB Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala (see paper)
28% identity, 34% coverage: 106:264/464 of query aligns to 53:191/345 of 6cgqB
Sites not aligning to the query:
6nmxA Threonine synthase from bacillus subtilis atcc 6633 with plp and appa (see paper)
28% identity, 34% coverage: 106:264/464 of query aligns to 55:193/350 of 6nmxA
Sites not aligning to the query:
>WP_013451358.1 NCBI__GCF_000183405.1:WP_013451358.1
MKYKSTRGKVNQLSFSETVLMGLADDGGLIIPEKIPQIGKEDILRLRDLPYKELALNIMG
YFIDDIPQSDLKKIIDDSYSTFDTEEVIPVVSFGGNLFIGEIFHGPTHAFKDIALQFLGN
LFSFILNQKGQKMNILGATSGDTGSAAIYGFKGKKDINIFILHPHGKVSPVQELQMTTVD
DKNVFNIAIEGTFDDCQFIVKSIFNDLEFKKRYSLGAINSINWSRVLAQIVYYFYTYFKS
TKDNNELPEVYFAVPTGNFGNIFAGFVARKMGLPIKKLILATNENNILTRFINNGDYSLS
KVVETYSPSMDIQIASNLERYLYFLYNEDSGILSEKMKEFEKNRSLSFQGNELKKIQSDF
ISVSTSNDQTLKMIKDFYEKYSYILDPHTACAINAVENVYNSDDIFIALATAHPAKFEDA
IVKAIGIKPEEPSRIKQIKGKPKKFTILKNSIEDVKRFIQETLS
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory