Comparing WP_013459153.1 NCBI__GCF_000183725.1:WP_013459153.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P56076 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see paper)
45% identity, 95% coverage: 2:228/239 of query aligns to 4:232/234 of P56076
2jgqA Kinetics and structural properties of triosephosphate isomerase from helicobacter pylori (see paper)
45% identity, 95% coverage: 2:228/239 of query aligns to 3:229/231 of 2jgqA
6neeB Crystal structure of a reconstructed ancestor of triosephosphate isomerase from eukaryotes (see paper)
37% identity, 93% coverage: 6:227/239 of query aligns to 11:248/252 of 6neeB
4y96A Crystal structure of triosephosphate isomerase from gemmata obscuriglobus (see paper)
38% identity, 95% coverage: 3:230/239 of query aligns to 6:249/250 of 4y96A
P36204 Bifunctional PGK/TIM; EC 2.7.2.3; EC 5.3.1.1 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
37% identity, 92% coverage: 1:219/239 of query aligns to 404:639/654 of P36204
Sites not aligning to the query:
6bveA Triosephosphate isomerase of synechocystis in complex with 2- phosphoglycolic acid (see paper)
36% identity, 95% coverage: 1:227/239 of query aligns to 4:238/242 of 6bveA
4y90A Crystal structure of triosephosphate isomerase from deinococcus radiodurans (see paper)
36% identity, 95% coverage: 2:227/239 of query aligns to 4:240/244 of 4y90A
3uwzA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with glycerol-2-phosphate (see paper)
35% identity, 96% coverage: 2:230/239 of query aligns to 6:253/254 of 3uwzA
3uwwA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with 3-phosphoglyceric acid (see paper)
35% identity, 96% coverage: 2:230/239 of query aligns to 6:253/254 of 3uwwA
3uwvA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with 2-phosphoglyceric acid (see paper)
35% identity, 96% coverage: 2:230/239 of query aligns to 7:254/255 of 3uwvA
3uwuA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with glycerol-3-phosphate (see paper)
35% identity, 96% coverage: 2:230/239 of query aligns to 5:252/253 of 3uwuA
Q6GIL6 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Staphylococcus aureus (strain MRSA252) (see paper)
35% identity, 96% coverage: 2:230/239 of query aligns to 5:252/253 of Q6GIL6
4bi7A Crystal structure of a mutant (c202a) of triosephosphate isomerase from giardia lamblia complexed with 2-phosphoglycolic acid (see paper)
34% identity, 93% coverage: 6:227/239 of query aligns to 10:248/256 of 4bi7A
3pf3A Crystal structure of a mutant (c202a) of triosephosphate isomerase from giardia lamblia derivatized with mmts (see paper)
34% identity, 93% coverage: 6:227/239 of query aligns to 10:248/256 of 3pf3A
P00942 Triosephosphate isomerase; TIM; Triose-phosphate isomerase; EC 5.3.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
34% identity, 93% coverage: 6:227/239 of query aligns to 10:244/248 of P00942
Sites not aligning to the query:
5eywA Crystal structure of litopenaeus vannamei triosephosphate isomerase complexed with 2-phosphoglycolic acid (see paper)
39% identity, 76% coverage: 46:227/239 of query aligns to 50:241/244 of 5eywA
Sites not aligning to the query:
2y63A Crystal structure of leishmanial e65q-tim complexed with bromohydroxyacetone phosphate (see paper)
34% identity, 95% coverage: 2:227/239 of query aligns to 6:245/249 of 2y63A
2y61A Crystal structure of leishmanial e65q-tim complexed with s-glycidol phosphate (see paper)
34% identity, 95% coverage: 2:227/239 of query aligns to 6:245/249 of 2y61A
2vxnA E65q-tim complexed with phosphoglycolohydroxamate at 0.82 a resolution (see paper)
34% identity, 95% coverage: 2:227/239 of query aligns to 6:245/249 of 2vxnA
1if2A X-ray structure of leishmania mexicana triosephosphate isomerase complexed with ipp (see paper)
34% identity, 95% coverage: 2:227/239 of query aligns to 6:245/249 of 1if2A
>WP_013459153.1 NCBI__GCF_000183725.1:WP_013459153.1
MILCANFKANKTRQETRAYMAVVESFVSANDITDTIIVFPPFTALEHDPRNVLIGVQNGY
PVKNGAFTGEIALEQLEEFGIKTILIGHSERRHILGETQEQIAAKFRFFAEQGFLIVYCV
GEPLEIREQGHEALMAYIEKQFEGIDLTYSDLVLAYEPVWAIGTGLTPSNSDIELLHGAL
RMKTTAPLLYGGSVKVDNAGEIMALENVDGVLVGSAALSANDFCDMIAQAVELNTEKGE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory