Comparing WP_013519098.1 NCBI__GCF_000204645.1:WP_013519098.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
59% identity, 98% coverage: 5:388/392 of query aligns to 5:376/376 of 4o23A
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
59% identity, 97% coverage: 5:386/392 of query aligns to 5:374/375 of 4pqaA
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
57% identity, 95% coverage: 16:389/392 of query aligns to 16:377/377 of 7t1qA
7lgpB Dape enzyme from shigella flexneri
53% identity, 99% coverage: 1:388/392 of query aligns to 3:377/377 of 7lgpB
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
49% identity, 98% coverage: 1:386/392 of query aligns to 5:378/380 of 5vo3A
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
49% identity, 98% coverage: 1:386/392 of query aligns to 1:374/377 of P44514
4op4B Crystal structure of the catalytic domain of dape protein from v.Cholerea in the zn bound form (see paper)
54% identity, 48% coverage: 3:192/392 of query aligns to 3:180/265 of 4op4B
Sites not aligning to the query:
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
48% identity, 49% coverage: 1:192/392 of query aligns to 3:182/258 of 4h2kA
Sites not aligning to the query:
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
32% identity, 40% coverage: 64:221/392 of query aligns to 89:236/426 of 3pfoA
Sites not aligning to the query:
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
26% identity, 98% coverage: 4:386/392 of query aligns to 5:378/381 of 8uw6B
Sites not aligning to the query:
2pokA Crystal structure of a m20 family metallo peptidase from streptococcus pneumoniae
24% identity, 92% coverage: 12:371/392 of query aligns to 30:442/458 of 2pokA
Sites not aligning to the query:
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
23% identity, 98% coverage: 4:386/392 of query aligns to 11:397/407 of P37111
Sites not aligning to the query:
Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 6 papers)
23% identity, 98% coverage: 2:386/392 of query aligns to 11:398/408 of Q03154
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
28% identity, 59% coverage: 72:301/392 of query aligns to 68:292/383 of 7uoiA
Q96KP4 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Peptidase A; Threonyl dipeptidase; EC 3.4.13.18 from Homo sapiens (Human)
23% identity, 68% coverage: 72:337/392 of query aligns to 92:417/475 of Q96KP4
Sites not aligning to the query:
Q8C165 N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Peptidase M20 domain-containing protein 1; PM20D1; EC 3.5.1.114; EC 3.5.1.14 from Mus musculus (Mouse) (see paper)
30% identity, 37% coverage: 67:210/392 of query aligns to 113:262/503 of Q8C165
Sites not aligning to the query:
Q9D1A2 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Threonyl dipeptidase; EC 3.4.13.18 from Mus musculus (Mouse) (see 2 papers)
22% identity, 78% coverage: 72:378/392 of query aligns to 92:463/475 of Q9D1A2
2zogA Crystal structure of mouse carnosinase cn2 complexed with zn and bestatin (see paper)
22% identity, 78% coverage: 72:378/392 of query aligns to 96:467/478 of 2zogA
2zofA Crystal structure of mouse carnosinase cn2 complexed with mn and bestatin (see paper)
22% identity, 78% coverage: 72:378/392 of query aligns to 96:467/478 of 2zofA
Q96KN2 Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase; EC 3.4.13.20 from Homo sapiens (Human) (see 4 papers)
29% identity, 44% coverage: 23:193/392 of query aligns to 82:246/507 of Q96KN2
Sites not aligning to the query:
>WP_013519098.1 NCBI__GCF_000204645.1:WP_013519098.1
MPSPTLLLTEQLIARPSVTPEDAGCLDLLAERLAPLGFACERLDSGPSSFRVCNLWAKRA
ATPTSQSQAAIKTVVFAGHTDVVPTGPVEQWSSAPFTPTQRDGRLYGRGASDMKTSIAAF
VVAVEEFLAATPAPAIAIAFLLTSDEEGPSVDGTKVVVEQLRARGERLDWCIVGEPTSVQ
STGDMIKNGRRGTLSGRLTVRGVQGHIAYPHLARNPIHQAVPALAELAATVWDRGNDFFP
PTSWQMSNIHGGTGATNVIPGEVAIDFNFRFCTESTAESLKERVHAVLDHHGLEYDLAWT
LGGQPFLTTPGELVGAVQQAIHAETGLTTELSTTGGTSDGRFIAQICPQVVELGPPNDSI
HKIDENIRLTDIEPLKNIYRRTLENLNAQAAA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory