Comparing WP_013530453.1 NCBI__GCF_000185905.1:WP_013530453.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
31% identity, 97% coverage: 5:380/386 of query aligns to 8:378/381 of 8uw6B
Sites not aligning to the query:
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
29% identity, 98% coverage: 3:380/386 of query aligns to 5:374/376 of 4o23A
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
29% identity, 98% coverage: 3:380/386 of query aligns to 5:374/375 of 4pqaA
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
31% identity, 86% coverage: 51:382/386 of query aligns to 54:380/380 of 5vo3A
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
31% identity, 86% coverage: 51:382/386 of query aligns to 50:376/377 of P44514
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
30% identity, 86% coverage: 51:383/386 of query aligns to 50:377/377 of 7t1qA
7lgpB Dape enzyme from shigella flexneri
29% identity, 85% coverage: 51:380/386 of query aligns to 52:375/377 of 7lgpB
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
27% identity, 96% coverage: 6:375/386 of query aligns to 13:373/383 of 7uoiA
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
28% identity, 67% coverage: 3:262/386 of query aligns to 12:279/407 of P37111
Sites not aligning to the query:
Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 6 papers)
29% identity, 58% coverage: 62:285/386 of query aligns to 73:303/408 of Q03154
Sites not aligning to the query:
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
26% identity, 79% coverage: 64:368/386 of query aligns to 99:408/426 of 3pfoA
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
38% identity, 32% coverage: 51:173/386 of query aligns to 52:182/258 of 4h2kA
Sites not aligning to the query:
4op4B Crystal structure of the catalytic domain of dape protein from v.Cholerea in the zn bound form (see paper)
40% identity, 29% coverage: 51:163/386 of query aligns to 50:165/265 of 4op4B
Sites not aligning to the query:
Q8P8J5 N-acetyl-L-citrulline deacetylase; ACDase; Acetylcitrulline deacetylase; EC 3.5.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
25% identity, 96% coverage: 7:378/386 of query aligns to 12:363/366 of Q8P8J5
Q8C165 N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Peptidase M20 domain-containing protein 1; PM20D1; EC 3.5.1.114; EC 3.5.1.14 from Mus musculus (Mouse) (see paper)
26% identity, 70% coverage: 7:276/386 of query aligns to 55:383/503 of Q8C165
Sites not aligning to the query:
2f7vA Structure of acetylcitrulline deacetylase complexed with one co (see paper)
25% identity, 96% coverage: 7:378/386 of query aligns to 13:358/360 of 2f7vA
3rzaA Crystal structure of a tripeptidase (sav1512) from staphylococcus aureus subsp. Aureus mu50 at 2.10 a resolution
22% identity, 86% coverage: 51:383/386 of query aligns to 58:373/373 of 3rzaA
Sites not aligning to the query:
P45494 Beta-Ala-Xaa dipeptidase; Beta-Ala-His dipeptidase; Peptidase V; EC 3.4.13.- from Lactobacillus delbrueckii subsp. lactis (see paper)
34% identity, 27% coverage: 68:173/386 of query aligns to 86:188/470 of P45494
Sites not aligning to the query:
1lfwA Crystal structure of pepv (see paper)
34% identity, 27% coverage: 68:173/386 of query aligns to 86:188/468 of 1lfwA
Sites not aligning to the query:
2pokA Crystal structure of a m20 family metallo peptidase from streptococcus pneumoniae
37% identity, 18% coverage: 60:129/386 of query aligns to 82:152/458 of 2pokA
Sites not aligning to the query:
>WP_013530453.1 NCBI__GCF_000185905.1:WP_013530453.1
MDSTQILEKLLAFPTVSRDSNLALVNYVADLLDAHGTASQIIHSEDGHKANLFATIGPTD
ASGIMLSGHTDVVPVDGQAWTLPPFEMTNRDGKLYGRGAADMKGFVACALAACLKAAKMT
LKTPLHLALSYDEEIGCIGVRSLVDMLQAAPHRPLLCIVGEPTDMQVATGHKGKLAARAL
CKGREGHSALAPLALNAIHLGCDFVAALRREQDRLVRDGARDGDYDISYTTVHVGKINAG
VALNIVPNLCQVDFEIRNVAADDPHEILDRLRKEAAHIASEASTIAPEAAIDIDITNTYP
GLDTPASSQAVAFVKSLTGANNTIKMAFGTEGGLFSRDLGTPTVVCGPGSMAQGHKPDEF
VSVEQMRRCDDMLEKLLKRLADQQLP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory