Comparing WP_013537942.1 NCBI__GCF_000185805.1:WP_013537942.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3e0iA Cu2+ substituted aquifex aeolicus kdo8ps in complex with pep (see paper)
60% identity, 97% coverage: 1:260/269 of query aligns to 3:261/263 of 3e0iA
2a21A Aquifex aeolicus kdo8ps in complex with pep, po4, and zn2+ (see paper)
60% identity, 97% coverage: 1:260/269 of query aligns to 3:261/263 of 2a21A
1jcyA Aquifex aeolicus kdo8p synthase in complex with r5p, pep and cadmium (see paper)
60% identity, 97% coverage: 1:260/269 of query aligns to 3:261/263 of 1jcyA
1fwwA Aquifex aeolicus kdo8p synthase in complex with pep, a5p and cadmium (see paper)
60% identity, 97% coverage: 1:260/269 of query aligns to 3:261/263 of 1fwwA
1fwtA Aquifex aeolicus kdo8p synthase in complex with pep, e4p and cadmium (see paper)
60% identity, 97% coverage: 1:260/269 of query aligns to 3:261/263 of 1fwtA
2nx3D Structural and mechanistic changes along an engineered path from metallo to non-metallo kdo8p synthase (see paper)
60% identity, 97% coverage: 1:260/269 of query aligns to 2:260/262 of 2nx3D
2nx1A Structural and mechanistic changes along an engineered path from metallo to non-metallo kdo8p synthase (see paper)
59% identity, 97% coverage: 1:260/269 of query aligns to 3:261/263 of 2nx1A
1pckA Aquifex aeolicus kdo8ps in complex with z-methyl-pep (see paper)
58% identity, 97% coverage: 1:260/269 of query aligns to 3:256/258 of 1pckA
3e12A Cu2+ substituted aquifex aeolicus kdo8ps in complex with kdo8p (see paper)
58% identity, 97% coverage: 1:260/269 of query aligns to 3:256/258 of 3e12A
1pe1A Aquifex aeolicus kdo8ps in complex with cadmium and 2-pga (see paper)
58% identity, 97% coverage: 1:260/269 of query aligns to 4:256/258 of 1pe1A
1pcwA Aquifex aeolicus kdo8ps in complex with cadmium and app, a bisubstrate inhibitor (see paper)
58% identity, 97% coverage: 1:260/269 of query aligns to 3:255/257 of 1pcwA
1jcxA Aquifex aeolicus kdo8p synthase in complex with api and cadmium (see paper)
57% identity, 97% coverage: 1:260/269 of query aligns to 3:253/255 of 1jcxA
4z1dA Structure of pep and zinc bound kdo8ps from h.Pylori (see paper)
50% identity, 94% coverage: 2:253/269 of query aligns to 3:254/256 of 4z1dA
3undB Substrate-bound crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from burkholderia pseudomallei (see paper)
54% identity, 80% coverage: 35:248/269 of query aligns to 53:268/284 of 3undB
Sites not aligning to the query:
1g7vA Crystal structures of kdo8p synthase in its binary complexes with the mechanism-based inhibitor (see paper)
51% identity, 76% coverage: 35:238/269 of query aligns to 52:257/284 of 1g7vA
Sites not aligning to the query:
1g7uA Crystal structures of kdo8p synthase in its binary complex with substrate phosphoenol pyruvate (see paper)
49% identity, 80% coverage: 35:248/269 of query aligns to 52:267/284 of 1g7uA
1x6uA Kdo8p synthase in it's binary complex with the product kdo8p (see paper)
47% identity, 80% coverage: 35:248/269 of query aligns to 52:255/272 of 1x6uA
Sites not aligning to the query:
1phwA Crystal structure of kdo8p synthase in its binary complex with substrate analog 1-deoxy-a5p (see paper)
47% identity, 80% coverage: 35:248/269 of query aligns to 52:255/272 of 1phwA
Sites not aligning to the query:
1phqA Crystal structure of kdo8p synthase in its binary complex with substrate analog e-fpep
47% identity, 80% coverage: 35:248/269 of query aligns to 52:255/272 of 1phqA
Sites not aligning to the query:
1gg0A Crystal structure analysis of kdop synthase at 3.0 a (see paper)
47% identity, 80% coverage: 35:248/269 of query aligns to 52:258/275 of 1gg0A
Sites not aligning to the query:
>WP_013537942.1 NCBI__GCF_000185805.1:WP_013537942.1
MIVIAGPCVIEDKGTVFEVARAVKELQSLYPEHTFIFKASFDKANRSSLDSFRGPGLERG
LEVLKEVKEELGLPVTTDIHEPWQAEKVAEVADVIQIPAFLCRQTDLLVAAAGTGKTVNI
KKGQFMAPWDMENAVEKVRRSGGREVWVTERGTTFGYNNLVVDFRSIPVMEEFADKVVFD
ATHSVQRPGGLGRASGGDRRFVPYLARAAVAVGADGLFFETHPNPDKALSDGPNMVPLNG
FRELIGKLIKLKSCVGELFDGEGEDIQNR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory