Comparing WP_013553760.1 NCBI__GCF_000186245.1:WP_013553760.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3t44A Crystal structure of mycobacterium tuberculosis indole glycerol phosphate synthase (igps) in complex with indole glycerol phosphate (igp) amd anthranilate
40% identity, 96% coverage: 4:260/268 of query aligns to 2:254/259 of 3t44A
6y88B Igps (indole-3-glycerol phosphate synthase) from pseudomonas aeruginosa in complex with substrate inhibitor rcdrp (see paper)
40% identity, 93% coverage: 4:252/268 of query aligns to 5:254/265 of 6y88B
3t55A Crystal structure of mycobacterium tuberculosis indole glycerol phosphate synthase (igps) in complex with phenoxymethyl benzoic acid (pmba)
40% identity, 96% coverage: 4:260/268 of query aligns to 2:254/258 of 3t55A
3t78A Crystal structure of mycobacterium tuberculosis indole glycerol phosphate synthase (igps) in complex with 5-fluoroanthranilate
40% identity, 96% coverage: 4:260/268 of query aligns to 2:252/257 of 3t78A
6y88G Igps (indole-3-glycerol phosphate synthase) from pseudomonas aeruginosa in complex with substrate inhibitor rcdrp (see paper)
45% identity, 78% coverage: 56:264/268 of query aligns to 48:253/253 of 6y88G
1vc4B Crystal structure of indole-3-glycerol phosphate synthase (trpc) from thermus thermophilus at 1.8 a resolution (see paper)
47% identity, 76% coverage: 56:260/268 of query aligns to 48:252/254 of 1vc4B
1lbfA Crystal structure of indole-3-glycerol phosphate syntase (igps)with reduced 1-(o-caboxyphenylamino)-1-deoxyribulose 5-phosphate (rcdrp) (see paper)
46% identity, 73% coverage: 56:250/268 of query aligns to 47:238/247 of 1lbfA
Sites not aligning to the query:
1jukA Indole-3-glycerolphosphate synthase from sulfolobus solfataricus in a trigonal crystal form (see paper)
46% identity, 73% coverage: 56:250/268 of query aligns to 47:238/247 of 1jukA
1igsA Indole-3-glycerolphosphate synthase from sulfolobus solfataricus at 2.0 a resolution (see paper)
46% identity, 73% coverage: 56:250/268 of query aligns to 47:238/247 of 1igsA
1a53A Complex of indole-3-glycerolphosphate synthase from sulfolobus solfataricus with indole-3-glycerolphosphate at 2.0 a resolution (see paper)
46% identity, 73% coverage: 56:250/268 of query aligns to 47:238/247 of 1a53A
3t40A Crystal structure of mycobacterium tuberculosis indole glycerol phosphate synthase (igps) complex with n-2-carboxyphenyl glycine (cpg)
38% identity, 96% coverage: 4:260/268 of query aligns to 2:240/251 of 3t40A
1jcmP Trpc stability mutant containing an engineered disulphide bridge and in complex with a cdrp-related substrate (see paper)
39% identity, 78% coverage: 57:266/268 of query aligns to 51:258/259 of 1jcmP
Sites not aligning to the query:
1piiA Three-dimensional structure of the bifunctional enzyme phosphoribosylanthranilate isomerase: indoleglycerolphosphate synthase from escherichia coli refined at 2.0 angstroms resolution (see paper)
39% identity, 78% coverage: 57:266/268 of query aligns to 51:258/452 of 1piiA
Sites not aligning to the query:
7etxA Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpc) from corynebacterium glutamicum (see paper)
42% identity, 78% coverage: 55:263/268 of query aligns to 52:258/472 of 7etxA
Sites not aligning to the query:
7etyA Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpc) from corynebacterium glutamicum in complex with reduced 1-(o-carboxyphenylamino)-1- deoxyribulose 5-phosphate (rcdrp) (see paper)
42% identity, 78% coverage: 55:263/268 of query aligns to 50:256/470 of 7etyA
Sites not aligning to the query:
4iwwA Computational design of an unnatural amino acid metalloprotein with atomic level accuracy (see paper)
43% identity, 73% coverage: 56:250/268 of query aligns to 47:238/247 of 4iwwA
4ou1A Crystal structure of a computationally designed retro-aldolase covalently bound to folding probe 1 [(6-methoxynaphthalen-2-yl) (oxiran-2-yl)methanol] (see paper)
41% identity, 73% coverage: 56:250/268 of query aligns to 47:238/247 of 4ou1A
5k7jA Structure of designed zinc binding protein ze2 bound to zn2+ (see paper)
41% identity, 73% coverage: 56:250/268 of query aligns to 47:231/240 of 5k7jA
3uxdA Designed protein ke59 r1 7/10h with dichlorobenzotriazole (dbt) (see paper)
41% identity, 73% coverage: 56:250/268 of query aligns to 47:238/247 of 3uxdA
4a2rA Structure of the engineered retro-aldolase ra95.5-5 (see paper)
41% identity, 73% coverage: 56:250/268 of query aligns to 47:238/247 of 4a2rA
Sites not aligning to the query:
>WP_013553760.1 NCBI__GCF_000186245.1:WP_013553760.1
MADILDEIIRKTRDDLERKKKEYSLDWLGRSLSFNPFVPRDVHPYLRSTPEDPYRIIAEV
KKASPSKGIIREDFDPLVIAQAYEKGGASALSVLTEPHWFKGNVEYLGMIRRYVSIPLLR
KDFIIDKYQLVEAVAYGADFVLLIAKALSRKELKELLEYTRHLGMEALVEIHDKADLVKA
IFAGADIIGINHRNLETFEMDMSLSERLIPLIPNSKIIVAESGINDHETVKHLSEVGADA
FLVGEHFMRQEDITGALRELKYGEQESE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory