Comparing WP_013644447.1 NCBI__GCF_000191585.1:WP_013644447.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 5 hits to proteins with known functional sites (download)
1ct9A Crystal structure of asparagine synthetase b from escherichia coli (see paper)
22% identity, 70% coverage: 2:438/621 of query aligns to 1:402/497 of 1ct9A
P22106 Asparagine synthetase B [glutamine-hydrolyzing]; AS-B; EC 6.3.5.4 from Escherichia coli (strain K12) (see 2 papers)
22% identity, 71% coverage: 1:438/621 of query aligns to 1:419/554 of P22106
P78753 Probable asparagine synthetase [glutamine-hydrolyzing]; Glutamine-dependent asparagine synthetase; EC 6.3.5.4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
31% identity, 41% coverage: 23:274/621 of query aligns to 24:249/557 of P78753
Sites not aligning to the query:
P08243 Asparagine synthetase [glutamine-hydrolyzing]; Cell cycle control protein TS11; Glutamine-dependent asparagine synthetase; EC 6.3.5.4 from Homo sapiens (Human) (see 7 papers)
32% identity, 16% coverage: 489:590/621 of query aligns to 406:511/561 of P08243
Sites not aligning to the query:
6gq3A Human asparagine synthetase (asns) in complex with 6-diazo-5-oxo-l- norleucine (don) at 1.85 a resolution (see paper)
40% identity, 9% coverage: 489:545/621 of query aligns to 393:452/509 of 6gq3A
Sites not aligning to the query:
>WP_013644447.1 NCBI__GCF_000191585.1:WP_013644447.1
MSAITGIFNRNGKNIKLSQFQKMNSKLSHRGRGNSKNWIEGNMALGHQMLWTTKESLIEE
LPFHDEDLKLIITSDARIDNREELSNILNIENSTEVSDSYYILKSYEKWGENCPKHLLGD
FSFAIWDDSQQKLFCARDHMGIKPFYYFLSNDVFIFGTEIKAIIDNDYVPYELNEYKLAL
FLMKDTENNKLTFYKDIFELPGGHSIVLNKSEFDISCYWQLDPNLEIIMDSEEDYVKKFL
ELFEESVKCRLRSCFPVGSELSGGLDSSSIVSVAKNIRGANDCFQPFCTFSQIFEETLEC
DEKNYINTLIDDTIEPFFINVDNISPLNDIDTILWYQDQPFYTPHITKQIQLYKHVQDRG
VHVLLSGQGGDQVLSLGNNYFKELAVTNQWKMLINEINDFSKMINTNRFTVFKEKVIYLL
LPYKLKKFIKIFLGINDESIINLEFAQSLGFDLKNYYNHLNDVNKLNTKEIHYKKITSSV
NETVFGTIDRRVANFGIEVRFPFYDKRLVEFCYAIPNEMKFKNGWNRYILREAMKNIMPD
EIRERVDKNNFSKSFEKSFIKYEFNYIQNILKNDKLIRNYVNLELFNSCRIDRFKESDFF
DLWIIILISIWLNQFKKRFNI
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory