Comparing WP_013645946.1 NCBI__GCF_000191585.1:WP_013645946.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5x6bJ Crystal structure of sepcyse-sepcyss in complex with trnacys from methanocaldococcus jannaschii (see paper)
60% identity, 97% coverage: 9:375/379 of query aligns to 14:373/377 of 5x6bJ
O30207 O-phospho-L-seryl-tRNA:Cys-tRNA synthase 1; Sep-tRNA:Cys-tRNA synthase 1; SepCysS 1; EC 2.5.1.73 from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see paper)
53% identity, 95% coverage: 18:377/379 of query aligns to 10:369/371 of O30207
2e7iA Crystal structure of sep-trna:cys-tRNA synthase from archaeoglobus fulgidus (see paper)
49% identity, 95% coverage: 18:377/379 of query aligns to 3:342/344 of 2e7iA
Q8KUU5 Cysteine desulfurase; CyD; EC 2.8.1.7 from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see paper)
33% identity, 37% coverage: 99:238/379 of query aligns to 331:465/626 of Q8KUU5
Sites not aligning to the query:
5b87A Crystal structure of a cysteine desulfurase from thermococcus onnurineus na1 in complex with alanine at 2.3 angstrom resolution (see paper)
30% identity, 36% coverage: 99:235/379 of query aligns to 103:234/397 of 5b87A
Sites not aligning to the query:
5b7uA Apo structure of cysteine desulfurase from thermococcus onnurineus na1 at 1.89a (see paper)
30% identity, 36% coverage: 99:235/379 of query aligns to 109:240/402 of 5b7uA
Sites not aligning to the query:
1t3iA Structure of slr0077/sufs, the essential cysteine desulfurase from synechocystis pcc 6803 (see paper)
36% identity, 21% coverage: 153:232/379 of query aligns to 160:238/406 of 1t3iA
Sites not aligning to the query:
Q9EXP2 Cysteine desulfurase; Selenocysteine beta-lyase; SCL; Selenocysteine lyase; Selenocysteine reductase; EC 2.8.1.7; EC 4.4.1.16 from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
29% identity, 46% coverage: 97:271/379 of query aligns to 116:286/412 of Q9EXP2
Sites not aligning to the query:
1kmkA E. Coli nifs/csdb protein at 2.20a with the cysteine perselenide intermediate (residue csz). (see paper)
30% identity, 42% coverage: 72:231/379 of query aligns to 78:239/405 of 1kmkA
Sites not aligning to the query:
1i29A Crystal structure of csdb complexed with l-propargylglycine (see paper)
30% identity, 42% coverage: 72:231/379 of query aligns to 78:239/405 of 1i29A
Sites not aligning to the query:
5db5A Crystal structure of plp-bound e. Coli sufs (cysteine persulfide intermediate) in space group p21
30% identity, 42% coverage: 72:231/379 of query aligns to 77:238/404 of 5db5A
Sites not aligning to the query:
6ndnA Crystal structure of selenocysteine lyase from escherichia coli
30% identity, 42% coverage: 72:231/379 of query aligns to 79:240/406 of 6ndnA
P77444 Cysteine desulfurase; Cysteine sulfinate desulfinase; CSD; Selenocysteine beta-lyase; SCL; Selenocysteine lyase; Selenocysteine reductase; EC 2.8.1.7; EC 3.13.1.-; EC 4.4.1.16 from Escherichia coli (strain K12) (see 2 papers)
30% identity, 42% coverage: 72:231/379 of query aligns to 79:240/406 of P77444
Sites not aligning to the query:
6o11A E. Coli cysteine desulfurase sufs c364a with a cys-aldimine intermediate (see paper)
30% identity, 42% coverage: 72:231/379 of query aligns to 79:240/406 of 6o11A
Sites not aligning to the query:
6o13A E. Coli cysteine desulfurase sufs h123a with a cys-ketimine intermediate (see paper)
36% identity, 23% coverage: 143:231/379 of query aligns to 154:239/405 of 6o13A
Sites not aligning to the query:
5ft8A Crystal structure of the complex between the cysteine desulfurase csda and the sulfur-acceptor csde in the persulfurated state at 2.50 angstroem resolution
24% identity, 63% coverage: 97:334/379 of query aligns to 107:347/401 of 5ft8A
Sites not aligning to the query:
Q46925 Cysteine desulfurase CsdA; Cysteine sulfinate desulfinase; CSD; Selenocysteine lyase; EC 2.8.1.7; EC 3.13.1.-; EC 4.4.1.16 from Escherichia coli (strain K12) (see 2 papers)
24% identity, 63% coverage: 97:334/379 of query aligns to 107:347/401 of Q46925
Sites not aligning to the query:
Q93WX6 Cysteine desulfurase 1, chloroplastic; NIFS-like protein 1; CpNifS1; Plastid sufS-like protein; Protein AtCpNifS; Selenocysteine lyase; EC 2.8.1.7; EC 4.4.1.16 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
23% identity, 73% coverage: 31:307/379 of query aligns to 89:380/463 of Q93WX6
Sites not aligning to the query:
P83788 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Pseudomonas fluorescens (see paper)
26% identity, 22% coverage: 137:218/379 of query aligns to 154:229/416 of P83788
Sites not aligning to the query:
1qz9A The three dimensional structure of kynureninase from pseudomonas fluorescens (see paper)
26% identity, 22% coverage: 137:218/379 of query aligns to 153:228/404 of 1qz9A
Sites not aligning to the query:
>WP_013645946.1 NCBI__GCF_000191585.1:WP_013645946.1
MDECQDYGLTRDTERKNLNLNPLQRGGVLPLEARKALYEFSDGYSVCDYCSGRLDEITKP
QINGFLEDLAGFINTDFARTVHGAREGKFAVMHALCEPGDTIVIDGNAHYTTHVAAERVG
LNMVDVPNTDYPNYEVTPESYKEVLDDLYDQGEEVSLVLLTHVDGNYGNLADARSIGKIA
HDAGVPLLLNCAYSMGRLPIDAKALNADFVVGSGHKSMAASGPIGVLGLKEEWADIILKR
SDRAQVKELEMLGCTSRGAPVATLMASFPHVIDRVKKWDVEVKETRKFVETLENIEGINQ
LGKKPKEHDLVRFETPIFDEIAKHHTRRGFFLYEELKKRKIVGIKRGQTKWFKCSVYGFS
AEQKEYIAETFVDIASKDY
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory