SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_013706282.1 NCBI__GCF_000195295.1:WP_013706282.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 3 hits to proteins with known functional sites (download)

5t61L Tungsten formylmethanofuran dehydrogenase subunit fwdF (see paper)
36% identity, 45% coverage: 69:131/140 of query aligns to 222:285/348 of 5t61L

query
sites
5t61L
V
 
I
K
 
K
V
 
T
Q
 
P
R
 
E
V
 
V
A
 
T
S
 
G
D
 
T
V
 
S
R
 
Y
R
 
I
N
 
D
E
 
P
E
 
E
R
 
L
C
|
C
Y
x
V
Q
x
N
C
|
C
G
|
G
V
 
W
C
|
C
T
 
Q
A
 
E
V
 
I
C
|
C
P
|
P
T
 
V
G
 
D
A
 
A
L
 
A
Y
 
T
V
 
V
K
 
T
R
 
K
P
 
P
-
 
F
E
 
E
M
 
G
E
 
E
I
 
L
V
 
I
F
 
I
D
 
D
P
 
Q
S
 
D
K
 
T
C
|
C
S
 
Q
A
|
A
C
|
C
E
|
E
L
 
T
C
|
C
C
 
V
P
 
M
V
 
V
C
|
C
P
|
P
A
 
C
R
 
N
A
x
V
M
 
L

Sites not aligning to the query:

8a8oD Paps reductase from methanothermococcus thermolithotrophicus refined to 1.45 a (see paper)
38% identity, 40% coverage: 78:133/140 of query aligns to 2:57/102 of 8a8oD

query
sites
8a8oD
V
x
I
R
 
R
R
 
I
N
 
I
E
 
E
E
 
E
R
 
I
C
|
C
Y
x
I
Q
x
G
C
|
C
G
|
G
V
 
L
C
|
C
T
 
T
A
 
K
V
 
V
C
|
C
P
|
P
T
 
G
G
 
N
A
 
L
L
 
L
Y
 
Y
V
 
Q
K
 
R
R
 
E
P
 
D
E
 
G
M
 
K
E
x
S
I
 
E
V
 
I
F
 
M
D
 
D
P
 
K
S
 
R
K
 
D
C
|
C
S
x
W
A
x
D
C
|
C
E
x
A
L
 
A
C
|
C
C
 
V
P
 
K
V
 
E
C
|
C
P
 
P
A
 
V
R
 
N
A
 
A
M
x
I
E
 
E
V
 
M

7p8nB Tmhydabc- t. Maritima hydrogenase with bridge closed (see paper)
37% identity, 37% coverage: 81:132/140 of query aligns to 563:613/613 of 7p8nB

query
sites
7p8nB
N
 
N
E
 
P
E
 
D
R
 
I
C
|
C
Y
 
K
Q
 
G
C
|
C
G
|
G
V
 
L
C
|
C
T
 
A
A
 
R
V
 
S
C
|
C
P
 
P
T
 
Q
G
 
N
A
 
A
L
 
I
Y
 
T
V
 
G
K
 
E
R
 
R
P
 
G
E
 
K
M
 
-
E
 
P
I
x
Y
V
 
T
F
x
I
D
 
D
P
 
Q
S
 
E
K
 
K
C
|
C
S
 
V
A
x
K
C
|
C
E
x
G
L
 
L
C
|
C
C
 
A
P
 
S
V
 
K
C
|
C
P
 
P
A
 
F
R
 
K
A
 
A
M
 
I
E
 
E

Sites not aligning to the query:

Query Sequence

>WP_013706282.1 NCBI__GCF_000195295.1:WP_013706282.1
MHAEILVLHFPKDIVDRPIIYRLVKDFDLEFNLLKATISPRREGIIVLELRGHPKNFRQG
VKYLKDSGVKVQRVASDVRRNEERCYQCGVCTAVCPTGALYVKRPEMEIVFDPSKCSACE
LCCPVCPARAMEVEINRNVV

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory