SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing WP_013707105.1 NCBI__GCF_000195295.1:WP_013707105.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 10 hits to proteins with known functional sites (download)

Q96XT4 2-oxoacid:ferredoxin oxidoreductase 2, subunit beta; OFOR2; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
47% identity, 86% coverage: 15:258/284 of query aligns to 11:268/304 of Q96XT4

query
sites
Q96XT4

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C12 (= C16) binding [4Fe-4S] cluster
C15 (= C19) binding [4Fe-4S] cluster
IGCS 44:47 (≠ IGQA 48:51) binding thiamine diphosphate
C46 (≠ Q50) binding [4Fe-4S] cluster
D90 (= D92) binding Mg(2+)
GD 91:92 (≠ GC 93:94) binding thiamine diphosphate
N118 (= N120) binding Mg(2+)
V120 (= V122) binding Mg(2+)
GL 122:123 (= GL 124:125) binding thiamine diphosphate
C197 (= C199) binding [4Fe-4S] cluster

5b46B 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - ligand free form (see paper)
47% identity, 86% coverage: 15:258/284 of query aligns to 8:265/301 of 5b46B

query
sites
5b46B

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binding magnesium ion: D87 (= D92), N115 (= N120), V117 (= V122)
binding iron/sulfur cluster: W8 (= W15), C9 (= C16), C12 (= C19), C43 (≠ Q50), C194 (= C199), T196 (≠ S201), Y197 (≠ F202)
binding thiamine diphosphate: I41 (= I48), G42 (= G49), C43 (≠ Q50), S44 (≠ A51), H62 (= H67), G86 (= G91), G88 (= G93), D89 (≠ C94), N115 (= N120), V117 (= V122), Y118 (= Y123), G119 (= G124), L120 (= L125), T121 (= T126)

P72579 2-oxoacid:ferredoxin oxidoreductase subunit beta; OFOR; EC 1.2.7.11 from Sulfolobus sp. (see paper)
43% identity, 94% coverage: 15:280/284 of query aligns to 11:295/305 of P72579

query
sites
P72579

W

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K49 (= K53) mutation to I: Strong decrease of the oxidoreductase activity with pyruvate, 2-oxobutyrate and 2-oxoglutarate.; mutation to R: Increase the oxidoreductase activity with pyruvate.; mutation to V: Slight decrease of the oxidoreductase activity with pyruvate, 2-oxobutyrate and 2-oxoglutarate.
L123 (= L125) mutation L->A,I: Strong decrease of the oxidoreductase activity with pyruvate, 2-oxobutyrate and 2-oxoglutarate.; mutation to N: Strong decrease of the oxidoreductase activity with pyruvate and 2-oxobutyrate. However, this mutant shows almost the same activity with 2-oxoglutarate as the wild-type.

Q96Y68 2-oxoacid:ferredoxin oxidoreductase 1, subunit beta; OFOR1; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see 2 papers)
43% identity, 94% coverage: 15:280/284 of query aligns to 11:295/305 of Q96Y68

query
sites
Q96Y68

W

W

C
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C

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P

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G

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C

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G

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C12 (= C16) binding [4Fe-4S] cluster
C15 (= C19) binding [4Fe-4S] cluster
C46 (≠ Q50) binding [4Fe-4S] cluster
K49 (= K53) mutation to I: Loss of oxidoreductase activity toward 2-oxoglutarate but retains its activity toward pyruvate.
D90 (= D92) binding Mg(2+)
GD 91:92 (≠ GC 93:94) binding thiamine diphosphate
N118 (= N120) binding Mg(2+)
V120 (= V122) binding Mg(2+)
GL 122:123 (= GL 124:125) binding thiamine diphosphate
K125 (= K127) Plays an important role in the binding of CoA; mutation to A: Shows a strong decrease of affinity for CoA and a poor inactivation by 4-fluoro-7-nitrobenzofurazan (NBD-F).
K173 (≠ D175) mutation to A: Same oxidoreductase activity as the wild-type.
C197 (= C199) binding [4Fe-4S] cluster

5b48B 2-oxoacid:ferredoxin oxidoreductase 1 from sulfolobus tokodai (see paper)
42% identity, 94% coverage: 15:280/284 of query aligns to 7:277/286 of 5b48B

query
sites
5b48B

W

W

C
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C

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P

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C

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G

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x
C

A
x
S

A

G

K

K

T

I

P

P

H

H

Y

F

L

T

N

P

A

I

N

S

L

G

F

V

N

H

G

T

L

L

H
|
H

G

G

R

R

S

A

L

I

P

A

V

F

A

A

T

T

G

G

C

I

R

K

L

L

A

S

N

N

H

P

Q

D

M

L

P

V

V

V

I

I

V

V

E

N

T

G

G

G

D
|
D

G
|
G

C
x
D

T

L

Y

L

G

G

E

I

G

G

G

A

N

G

H

H

F

F

L

V

A

A

I

G

R

R

N

N

I

V

N

D

I

M

T

V

L

V

L

I

V

L

H

H

N

D

N
|
N

Q

G

V
|
V

Y
|
Y

G
|
G

L
|
L

T

T

K

K

G

G

Q

Q

A

A

S

S

P

P

T

T

S

L

D

K

E

R

G

G

F

E

I

N

T

I

K

N

A

-

Q

-

P

-

H

-

G

-

V

-

Y

-

A

-

A

D

A

A

F

V

N

N

P

P

I

I

A

A

V

L

A

A

V

I

A

S

L

S

H

G

A

Y

G

T

F

F

V

V

A

A

R

R

S

G

F

Y

A

A

G

Y

F

D

E

V

D

K

H

H

L

L

T

K

E

E

M

L

I

I

K

K

Q

S

A

A

I

I

S

K

H

H

P

K

G

G

F

L

A

A

L

L

V

I

D

D

I

V

L

L

Q

Q

P

P

C
|
C

V

P

S
x
T

F

Y

N

N

K

D

V

I

N

N

T

T

F

K

A

E

W

W

Y

R

K

I

N

Y

R

K

C

L

Y

D

R

T

L

L

P

P

E

D

T

-

Y

W

D

D

P

P

T

V

-

V

-

K

-

P

-

E

-

V

-

N

-

E

D

K

W

I

S

K

A

R

A

A

I

I

L

D

K

K

A

S

N

L

E

E

W

W

G

G

D

D

Q

-

I

I

P

P

L

I

G

G

V

I

I

F

S

Y

K

Q

N

N

S

E

R

L

-

V

P

P

P

S

F

Y

E

E

A

E

H

R

F

I

D

K

C

A

-

N

-

S

-

P

-

A

-

Y

L

L

G

D

H

Y

T

T

P

P

L

-

A

A

R

K

Q

Q

Q

L

V

I

D

E

K

K

-

E

A

G

K

K

L

L

K

T

A

T

F

I

I

I

binding magnesium ion: D84 (= D92), N112 (= N120), V114 (= V122)
binding iron/sulfur cluster: C8 (= C16), C11 (= C19), C42 (≠ Q50), C183 (= C199), T185 (≠ S201)
binding 2-[(2E)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2-(1-oxidanylpropylidene)-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate: I40 (= I48), G41 (= G49), C42 (≠ Q50), S43 (≠ A51), H59 (= H67), G85 (= G93), D86 (≠ C94), N112 (= N120), V114 (= V122), Y115 (= Y123), G116 (= G124), L117 (= L125)

5b47B 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - pyruvate complex (see paper)
44% identity, 85% coverage: 15:255/284 of query aligns to 4:236/275 of 5b47B

query
sites
5b47B

W

W

C
|
C

P

P

G

G

C
|
C

G

G

N

D

F

F

R

G

I

I

L

L

A

R

A

A

L

E

K

E

K

M

A

A

L

I

V

R

E

E

S

L

N

G

L

I

T

N

P

P

H

K

E

S

V

V

I

V

F

I

V

V

S

S

G

G

I
|
I

G
|
G

Q
x
C

A
x
S

A

G

K

K

T

I

P

P

H

H

Y

F

L

M

N

N

A

L

N

P

L

I

-

S

-

G

F

V

N

H

G

T

L

L

H
|
H

G

G

R

R

S

S

L

I

P

A

V

F

A

A

T

T

G

G

C

I

R

K

L

L

A

S

N

N

H

P

Q

S

M

L

P

E

V

V

I

I

V

V

E

N

T

V

G

G

D
|
D

G
|
G

C
x
D

T

G

Y

L

G

G

E

I

G

G

G

M

N

G

H

H

F

F

L

V

A

H

A

L

I

G

R

R

N

N

I

I

N

D

I

I

T

A

L

V

L

L

V

V

H

H

N

N

N
|
N

Q

G

V
|
V

Y
|
Y

G

G

L
|
L

T

-

K

-

G

-

Q

Q

A

A

S

S

P

P

T

T

S

L

D

H

E

R

G

G

F

-

I

-

T

-

K

-

A

-

Q

-

P

-

H

-

G

E

V

N

Y

I

A

M

A

D

A

A

F

V

N

N

P

P

I

L

A

A

V

V

A

A

V

L

A

A

L

A

H

G

A

Y

G

T

F

F

V

V

A

A

R

R

S

G

F

Y

A

A

G

Y

F

D

E

V

D

M

H

H

L

L

T

K

E

E

M

L

I

I

K

K

Q

K

A

A

I

I

S

L

H

H

P

K

G

G

F

S

A

A

L

L

V

V

D

D

I

I

L

L

Q

Q

P

P

C
|
C

V

P

S

T

F

Y

N

-

K

-

V

-

N

-

T

-

F

-

A

-

W

-

Y

-

K

-

N

-

R

R

C

V

Y

Y

R

K

L

L

P

D

E

N

T

V

-

P

-

G

Y

W

D

D

P

P

T

V

-

V

-

R

-

K

-

E

-

A

-

Q

-

K

D

K

W

F

S

E

A

Q

A

A

I

I

L

M

K

K

A

S

N

Y

E

E

W

W

G

G

D

E

Q

K

I

I

P

P

L

I

G

G

V

I

I

F

S

Y

K

Q

N

N

S

E

R

L

-

V

P

P

P

T

F

F

E

E

binding magnesium ion: D83 (= D92), N111 (= N120)
binding iron/sulfur cluster: C5 (= C16), C8 (= C19), C39 (≠ Q50), C179 (= C199)
binding thiamine diphosphate: I37 (= I48), G38 (= G49), C39 (≠ Q50), S40 (≠ A51), H58 (= H67), G84 (= G93), D85 (≠ C94), N111 (= N120), V113 (= V122), Y114 (= Y123), L116 (= L125)

6n2oD 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound (see paper)
36% identity, 87% coverage: 13:258/284 of query aligns to 22:267/291 of 6n2oD

query
sites
6n2oD

T

T

A

T

W
|
W

C
|
C

P

P

G

G

C
|
C

G

G

N

H

F

F

R

G

I

I

L

L

A

N

A

G

L

V

K

Y

K

R

A

A

L

M

V

A

E

E

S

L

N

G

L

I

T

D

P

S

H

T

E

K

V

F

I

A

F

A

V

I

S

S

G

G

I
|
I

G
|
G

Q
x
C

A
x
S

A

S

K
x
R

T

M

P

P

H

Y

Y

F

L

V

N

D

A

S

N

Y

L

K

F

M

N

H

G

T

L

L

H
|
H

G

G

R

R

S

A

L

G

P

A

V

V

A

A

T

T

G

G

C

T

R

Q

L

V

A

A

N

R

H

P

Q

D

M

L

P

C

V

V

I

V

V

V

E

A

T

G

G

G

D
|
D

G
|
G

C
x
D

T

G

Y

F

G

S

E

I

G

G

N

G

H

H

F

M

L

P

A

H

A

M

I

A

R

R

R

K

N

N

I

V

N

N

I

M

T

T

L

Y

L

V

V

L

H

M

N

D

N
|
N

Q

G

V
x
I

Y

Y

G
|
G

L
|
L

T
|
T

K
|
K

G

G

Q

Q

A

Y

S

S

P

P

T

T

S

S

D

R

E

P

G

E

F

M

I

T

T

A

K

Y

A

T

Q

T

P

P

H

Y

G

G

V

G

Y

P

A

E

A

N

A

P

F

M

N

N

P

P

I

L

A

L

V

Y

A

M

V

L

A

T

L

Y

H

G

A

A

G

T

F

Y

V

V

A

A

R

Q

S

A

F

F

A

A

G

G

F

K

E

P

D

K

H

D

L

C

T

A

E

E

M

L

I

I

K

K

Q

G

A

A

I

M

S

E

H

H

P

E

G

G

F

F

A

A

L

Y

V

V

D

N

I

I

L

F

Q

S

P

Q

C
|
C

V

P

S
x
T

F
|
F

N

N

K

K

V

I

N

D

T

T

F

V

A

D

W

F

Y

Y

K

R

N

D

R

L

C

V

Y

E

R

P

L

I

P

P

E

E

T

D

Y

H

D

D

P

T

T

S

D

D

W

L

S

G

A

A

I

M

L

E

K

L

A

A

N

R

E

R

W

P

G

G

D

G

Q

K

I

A

P

P

L

T

G

G

V

L

I

L

S

Y

K

K

N

T

S

S

R

A

P

P

P

T

F

L

E

D

A

Q

H

N

F

L

binding magnesium ion: D101 (= D92), N129 (= N120), I131 (≠ V122)
binding succinyl-coenzyme a: I57 (= I48), R62 (≠ K53), L134 (= L125), K136 (= K127)
binding iron/sulfur cluster: W24 (= W15), C25 (= C16), C28 (= C19), C59 (≠ Q50), C208 (= C199), T210 (≠ S201), F211 (= F202)
binding thiamine diphosphate: I57 (= I48), G58 (= G49), C59 (≠ Q50), S60 (≠ A51), H76 (= H67), G102 (= G93), D103 (≠ C94), N129 (= N120), I131 (≠ V122), G133 (= G124), L134 (= L125), T135 (= T126)

6n2oB 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound (see paper)
36% identity, 87% coverage: 13:258/284 of query aligns to 22:267/291 of 6n2oB

query
sites
6n2oB

T

T

A

T

W
|
W

C
|
C

P

P

G

G

C
|
C

G

G

N

H

F

F

R

G

I

I

L

L

A

N

A

G

L

V

K

Y

K

R

A

A

L

M

V

A

E

E

S

L

N

G

L

I

T

D

P

S

H

T

E

K

V

F

I

A

F

A

V

I

S

S

G

G

I
|
I

G
|
G

Q
x
C

A
x
S

A

S

K
x
R

T

M

P

P

H

Y

Y

F

L

V

N

D

A

S

N

Y

L

K

F

M

N

H

G

T

L

L

H
|
H

G

G

R

R

S

A

L

G

P

A

V

V

A

A

T

T

G

G

C

T

R

Q

L

V

A

A

N

R

H

P

Q

D

M

L

P

C

V

V

I

V

V

V

E

A

T

G

G

G

D
|
D

G
|
G

C
x
D

T

G

Y

F

G

S

E

I

G

G

N

G

H

H

F

M

L

P

A

H

A

M

I

A

R

R

R

K

N

N

I

V

N

N

I

M

T

T

L

Y

L

V

V

L

H

M

N

D

N
|
N

Q

G

V
x
I

Y
|
Y

G
|
G

L
|
L

T
|
T

K
|
K

G

G

Q

Q

A

Y

S

S

P

P

T

T

S

S

D

R

E

P

G

E

F

M

I

T

T

A

K
x
Y

A

T

Q

T

P

P

H

Y

G

G

V

G

Y

P

A

E

A

N

A

P

F

M

N

N

P

P

I

L

A

L

V

Y

A

M

V

L

A

T

L

Y

H

G

A

A

G

T

F

Y

V

V

A

A

R

Q

S

A

F

F

A

A

G

G

F

K

E

P

D

K

H

D

L

C

T

A

E

E

M

L

I

I

K

K

Q

G

A

A

I

M

S

E

H

H

P

E

G

G

F

F

A

A

L

Y

V

V

D

N

I

I

L

F

Q

S

P

Q

C
|
C

V

P

S
x
T

F
|
F

N

N

K

K

V

I

N

D

T

T

F

V

A

D

W

F

Y

Y

K

R

N

D

R

L

C

V

Y

E

R

P

L

I

P

P

E

E

T

D

Y

H

D

D

P

T

T

S

D

D

W

L

S

G

A

A

I

M

L

E

K

L

A

A

N

R

E

R

W

P

G

G

D

G

Q

K

I

A

P

P

L

T

G

G

V

L

I

L

S

Y

K

K

N

T

S

S

R

A

P

P

P

T

F

L

E

D

A

Q

H

N

F

L

binding 2-oxoglutaric acid: R62 (≠ K53), L134 (= L125)
binding coenzyme a: K136 (= K127), Y150 (≠ K141)
binding magnesium ion: D101 (= D92), N129 (= N120), I131 (≠ V122)
binding iron/sulfur cluster: W24 (= W15), C25 (= C16), C28 (= C19), C59 (≠ Q50), C208 (= C199), T210 (≠ S201), F211 (= F202)
binding thiamine diphosphate: I57 (= I48), G58 (= G49), C59 (≠ Q50), S60 (≠ A51), H76 (= H67), G102 (= G93), D103 (≠ C94), N129 (= N120), I131 (≠ V122), Y132 (= Y123), G133 (= G124), L134 (= L125), T135 (= T126)

6n2nB Crystal structure of 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus (see paper)
36% identity, 87% coverage: 13:258/284 of query aligns to 22:267/291 of 6n2nB

query
sites
6n2nB

T

T

A

T

W
|
W

C
|
C

P

P

G

G

C
|
C

G

G

N
x
H

F

F

R

G

I

I

L

L

A

N

A

G

L

V

K

Y

K

R

A

A

L

M

V

A

E

E

S

L

N

G

L

I

T

D

P

S

H

T

E

K

V

F

I

A

F

A

V

I

S

S

G

G

I
|
I

G
|
G

Q
x
C

A
x
S

A

S

K

R

T

M

P

P

H

Y

Y

F

L

V

N

D

A

S

N

Y

L

K

F

M

N

H

G

T

L

L

H
|
H

G

G

R

R

S

A

L

G

P

A

V

V

A

A

T

T

G

G

C

T

R

Q

L

V

A

A

N

R

H

P

Q

D

M

L

P

C

V

V

I

V

V

V

E

A

T

G

G
|
G

D
|
D

G
|
G

C
x
D

T

G

Y

F

G

S

E

I

G

G

N

G

H

H

F

M

L

P

A

H

A

M

I

A

R

R

R

K

N

N

I

V

N

N

I

M

T

T

L

Y

L

V

V

L

H

M

N

D

N
|
N

Q

G

V
x
I

Y
|
Y

G
|
G

L
|
L

T
|
T

K

K

G

G

Q

Q

A

Y

S

S

P

P

T

T

S

S

D

R

E

P

G

E

F

M

I

T

T

A

K

Y

A

T

Q

T

P

P

H

Y

G

G

V

G

Y

P

A

E

A

N

A

P

F

M

N

N

P

P

I

L

A

L

V

Y

A

M

V

L

A

T

L

Y

H

G

A

A

G

T

F

Y

V

V

A

A

R

Q

S

A

F

F

A

A

G

G

F

K

E

P

D

K

H

D

L

C

T

A

E

E

M

L

I

I

K

K

Q

G

A

A

I

M

S

E

H

H

P

E

G

G

F

F

A

A

L

Y

V

V

D

N

I

I

L

F

Q

S

P

Q

C
|
C

V

P

S
x
T

F
|
F

N

N

K

K

V

I

N

D

T

T

F

V

A

D

W

F

Y

Y

K

R

N

D

R

L

C

V

Y

E

R

P

L

I

P

P

E

E

T

D

Y

H

D

D

P

T

T

S

D

D

W

L

S

G

A

A

I

M

L

E

K

L

A

A

N

R

E

R

W

P

G

G

D

G

Q

K

I

A

P

P

L

T

G

G

V

L

I

L

S

Y

K

K

N

T

S

S

R

A

P

P

P

T

F

L

E

D

A

Q

H

N

F

L

binding magnesium ion: D101 (= D92), N129 (= N120), I131 (≠ V122)
binding iron/sulfur cluster: W24 (= W15), C25 (= C16), C28 (= C19), H30 (≠ N21), C59 (≠ Q50), C208 (= C199), T210 (≠ S201), F211 (= F202)
binding thiamine diphosphate: I57 (= I48), G58 (= G49), C59 (≠ Q50), S60 (≠ A51), H76 (= H67), G100 (= G91), D101 (= D92), G102 (= G93), D103 (≠ C94), N129 (= N120), I131 (≠ V122), Y132 (= Y123), G133 (= G124), L134 (= L125), T135 (= T126)

8x3zB Thdp-dependent hka synthase
26% identity, 50% coverage: 53:195/284 of query aligns to 382:502/511 of 8x3zB

query
sites
8x3zB

K

K

T

E

P

S

H

Y

Y

T

L

Y

N

E

A

I

N

N

L

V

F
x
H

N

F

G

G

L

A

H
x
M

G

G

R

S

S

G

L

I

P

G

V

S

A

A

T

I

G

G

C

S

R

K

L

L

A

A

N

E

H

P

Q

E

M

R

P

P

V

V

I

V

V

C

E

I

T

T

G
|
G

D
|
D

G
|
G

C
|
C

T

F

Y

F

G

M

E

H

G

-

G

G

N

M

H

E

F

L

L

L

A

T

A

A

I

K

R

E

R

Y

N

N

I

L

N

P

I

I

T

L

L

F

L

V

V

V

H

M

N

N

N
|
N

Q

A

V
x
R

Y
x
L

G
|
G

L

M

T

S

K

A

G

F

Q

E

A

Q

S

E

P

P

T

V

S

-

D

-

E

-

G

-

F

-

I

-

T

-

K

-

A

-

Q

-

P

-

H

-

G

-

V

-

Y

-

A

-

F

-

N

N

P

I

I

S

A

A

V

M

A

A

V

A

A

A

L

M

H

-

A

-

G

G

F

I

V

P

A

S

R

H

S

R

F

V

A

S

G

E

F

M

E

E

D

D

H

L

L

T

T

E

E

E

M

R

I

V

K

Q

Q

E

A

L

I

L

S

S

H

H

P

N

G

G

F

P

A

A

L

V

V

L

D

E

I

V

binding adenosine-5'-diphosphate: H392 (≠ F63)
binding magnesium ion: D421 (= D92), N448 (= N120), R450 (≠ V122)
binding thiamine diphosphate: M396 (≠ H67), G420 (= G91), D421 (= D92), G422 (= G93), C423 (= C94), N448 (= N120), R450 (≠ V122), L451 (≠ Y123), G452 (= G124)

Sites not aligning to the query:

binding adenosine-5'-diphosphate: 88, 90, 206, 207, 208, 230, 232, 272, 273, 274, 297, 298, 316, 317
binding thiamine diphosphate: 368, 370

Query Sequence

>WP_013707105.1 NCBI__GCF_000195295.1:WP_013707105.1
MMLSESIYGNYETAWCPGCGNFRILAALKKALVESNLTPHEVIFVSGIGQAAKTPHYLNA
NLFNGLHGRSLPVATGCRLANHQMPVIVETGDGCTYGEGGNHFLAAIRRNINITLLVHNN
QVYGLTKGQASPTSDEGFITKAQPHGVYAAAFNPIAVAVALHAGFVARSFAGFEDHLTEM
IKQAISHPGFALVDILQPCVSFNKVNTFAWYKNRCYRLPETYDPTDWSAAILKANEWGDQ
IPLGVISKNSRPPFEAHFDCLGHTPLARQQVDKAKLKAFITHYR

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory