Comparing WP_013722399.1 NCBI__GCF_000204645.1:WP_013722399.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4ur8A Crystal structure of keto-deoxy-d-galactarate dehydratase complexed with 2-oxoadipic acid (see paper)
54% identity, 98% coverage: 1:297/303 of query aligns to 1:296/304 of 4ur8A
5hwnB Crystal structure of keto-deoxy-d-galactarate dehydratase complexed with pyruvate (see paper)
54% identity, 98% coverage: 1:297/303 of query aligns to 1:296/310 of 5hwnB
Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
31% identity, 87% coverage: 10:274/303 of query aligns to 1:270/294 of Q8UGL3
4i7wA Agrobacterium tumefaciens dhdps with lysine and pyruvate
32% identity, 79% coverage: 10:248/303 of query aligns to 1:239/294 of 4i7wA
7mjfA Crystal structure of candidatus liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
29% identity, 89% coverage: 19:289/303 of query aligns to 10:279/296 of 7mjfA
Sites not aligning to the query:
7lvlA Dihydrodipicolinate synthase bound with allosteric inhibitor (s)- lysine from candidatus liberibacter solanacearum
29% identity, 89% coverage: 19:289/303 of query aligns to 10:279/296 of 7lvlA
4dxvA Crystal structure of dihydrodipicolinate synthase from acinetobacter baumannii complexed with mg and cl ions at 1.80 a resolution
34% identity, 57% coverage: 19:192/303 of query aligns to 10:186/291 of 4dxvA
Sites not aligning to the query:
3u8gA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with oxalic acid at 1.80 a resolution
34% identity, 57% coverage: 19:192/303 of query aligns to 10:186/291 of 3u8gA
Sites not aligning to the query:
3tdfA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 2-ketobutanoic acid at 1.99 a resolution
34% identity, 57% coverage: 19:192/303 of query aligns to 10:186/291 of 3tdfA
Sites not aligning to the query:
3tceA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 5-hydroxylysine at 2.6 a resolution
34% identity, 57% coverage: 19:192/303 of query aligns to 10:186/291 of 3tceA
Sites not aligning to the query:
3rk8A Crystal structure of the chloride inhibited dihydrodipicolinate synthase from acinetobacter baumannii complexed with pyruvate at 1.8 a resolution
34% identity, 57% coverage: 19:192/303 of query aligns to 10:186/291 of 3rk8A
Sites not aligning to the query:
3pueB Crystal structure of the complex of dhydrodipicolinate synthase from acinetobacter baumannii with lysine at 2.6a resolution
34% identity, 57% coverage: 19:192/303 of query aligns to 10:186/291 of 3pueB
Sites not aligning to the query:
Q07607 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; Protein MosA; EC 4.3.3.7 from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
29% identity, 95% coverage: 10:298/303 of query aligns to 1:286/292 of Q07607
P9WP25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
28% identity, 94% coverage: 14:298/303 of query aligns to 15:294/300 of P9WP25
5j5dA Crystal structure of dihydrodipicolinate synthase from mycobacterium tuberculosis in complex with alpha-ketopimelic acid (see paper)
28% identity, 94% coverage: 14:298/303 of query aligns to 12:291/297 of 5j5dA
1xxxA Crystal structure of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis (see paper)
28% identity, 94% coverage: 14:298/303 of query aligns to 11:290/296 of 1xxxA
3l21B The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis - dhdps- a204r
28% identity, 94% coverage: 14:298/303 of query aligns to 10:289/295 of 3l21B
1o5kA Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
32% identity, 50% coverage: 25:174/303 of query aligns to 16:169/295 of 1o5kA
Sites not aligning to the query:
Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
32% identity, 50% coverage: 25:174/303 of query aligns to 15:168/294 of Q9X1K9
4m19A Dihydrodipicolinate synthase from c. Jejuni with pyruvate bound to the active site and lysine bound to allosteric site (see paper)
35% identity, 61% coverage: 7:192/303 of query aligns to 1:188/296 of 4m19A
Sites not aligning to the query:
>WP_013722399.1 NCBI__GCF_000204645.1:WP_013722399.1
MTPQDLKNVMGSGLLSFPITDFDANGDFDAKSYAARLEWLAPFGASALFAAGGTGEYFSL
TAGEYPAIIRTAVDTCRGKVPIIAGAGGPTRFAIECAQAAEKAGAHGILLMPHYMTEASQ
EGLAAHVEAVCKSVDFGVIIYNRGVSRYTPETVARLCERNPNLVGFKDGVGDIEGMASMF
LAMGDRLAYLGGLPTAEVYAAAYKALGTPVYSSAVFNFIPRTAMRFYEAVKNDDQATQHQ
LLKDFFMPYLKIRNRSAGYAVSIIKAGARIVGHPAGPVRPPLADLQPDEVEMLAALIRKV
EQA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory