Comparing WP_013984427.1 NCBI__GCF_000013785.1:WP_013984427.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 5 hits to proteins with known functional sites (download)
1ox5A Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerophosphate synthase (see paper)
31% identity, 97% coverage: 1:205/212 of query aligns to 4:211/532 of 1ox5A
Sites not aligning to the query:
1ox4B Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerophosphate synthase (see paper)
31% identity, 97% coverage: 1:205/212 of query aligns to 4:211/538 of 1ox4B
Sites not aligning to the query:
P33734 Imidazole glycerol phosphate synthase hisHF; IGP synthase; IGPS; ImGP synthase; EC 4.3.2.10; EC 3.5.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
31% identity, 97% coverage: 1:205/212 of query aligns to 1:208/552 of P33734
Sites not aligning to the query:
7ac8B Molecular basis for the unique allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex. (see paper)
35% identity, 77% coverage: 42:204/212 of query aligns to 46:194/202 of 7ac8B
2ywcA Crystal structure of gmp synthetase from thermus thermophilus in complex with xmp
26% identity, 98% coverage: 4:210/212 of query aligns to 2:185/475 of 2ywcA
Sites not aligning to the query:
>WP_013984427.1 NCBI__GCF_000013785.1:WP_013984427.1
MQTVAVIDYGMGNLHSVAKALEHVGAGRVLITSDAQVIREADRVVFPGVGAIRDCMAEIR
RLGFDELVREVSQDRPFLGICVGMQALMERSEENDGVDCIGLFPGQVRFFGKDLVEDGEH
LKVPHMGWNEVKQAVDHPLWHAIPDNGRFYFVHSYYIEAGNPRQVVGRGHYGKDFAAALA
EGSRFAVQFHPEKSHTHGLQLLQNFAAWDGRW
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory