Comparing WP_014149056.1 NCBI__GCF_000968535.2:WP_014149056.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
4dxvA Crystal structure of dihydrodipicolinate synthase from acinetobacter baumannii complexed with mg and cl ions at 1.80 a resolution
28% identity, 99% coverage: 4:297/298 of query aligns to 2:291/291 of 4dxvA
3u8gA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with oxalic acid at 1.80 a resolution
28% identity, 99% coverage: 4:297/298 of query aligns to 2:291/291 of 3u8gA
3tdfA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 2-ketobutanoic acid at 1.99 a resolution
28% identity, 99% coverage: 4:297/298 of query aligns to 2:291/291 of 3tdfA
3tceA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 5-hydroxylysine at 2.6 a resolution
28% identity, 99% coverage: 4:297/298 of query aligns to 2:291/291 of 3tceA
3rk8A Crystal structure of the chloride inhibited dihydrodipicolinate synthase from acinetobacter baumannii complexed with pyruvate at 1.8 a resolution
28% identity, 99% coverage: 4:297/298 of query aligns to 2:291/291 of 3rk8A
3pueB Crystal structure of the complex of dhydrodipicolinate synthase from acinetobacter baumannii with lysine at 2.6a resolution
28% identity, 99% coverage: 4:297/298 of query aligns to 2:291/291 of 3pueB
7kg2A Dihydrodipicolinate synthase (dhdps) from c.Jejuni, h59k mutant with pyruvate bound in the active site and l-histidine bound at the allosteric site
26% identity, 79% coverage: 6:239/298 of query aligns to 6:240/296 of 7kg2A
6u01B Dihydrodipicolinate synthase (dhdps) from c.Jejuni, n84d mutant with pyruvate bound in the active site (see paper)
28% identity, 79% coverage: 6:239/298 of query aligns to 6:240/296 of 6u01B
7kkdB Dihydrodipicolinate synthase (dhdps) from c.Jejuni, n84a mutant with pyruvate bound in the active site and r,r-bislysine bound at the allosteric site
26% identity, 79% coverage: 6:239/298 of query aligns to 16:250/306 of 7kkdB
4m19A Dihydrodipicolinate synthase from c. Jejuni with pyruvate bound to the active site and lysine bound to allosteric site (see paper)
26% identity, 79% coverage: 6:239/298 of query aligns to 6:240/296 of 4m19A
3di1B Crystal structure of the staphylococcus aureus dihydrodipicolinate synthase-pyruvate complex (see paper)
28% identity, 80% coverage: 9:245/298 of query aligns to 10:238/291 of 3di1B
Q5HG25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Staphylococcus aureus (strain COL) (see paper)
28% identity, 81% coverage: 4:245/298 of query aligns to 5:238/295 of Q5HG25
5ud6C Crystal structure of dhdps from cyanidioschyzon merolae with lysine bound
29% identity, 67% coverage: 8:208/298 of query aligns to 8:214/299 of 5ud6C
3s8hA Structure of dihydrodipicolinate synthase complexed with 3- hydroxypropanoic acid(hpa)at 2.70 a resolution
30% identity, 70% coverage: 6:214/298 of query aligns to 4:214/292 of 3s8hA
3puoA Crystal structure of dihydrodipicolinate synthase from pseudomonas aeruginosa(psdhdps)complexed with l-lysine at 2.65a resolution (see paper)
30% identity, 70% coverage: 6:214/298 of query aligns to 4:214/292 of 3puoA
Sites not aligning to the query:
Q704D1 2-dehydro-3-deoxy-D-gluconate/2-dehydro-3-deoxy-phosphogluconate aldolase; KD(P)G aldolase; EC 4.1.2.14; EC 4.1.2.51 from Thermoproteus tenax (see paper)
25% identity, 73% coverage: 19:236/298 of query aligns to 34:248/306 of Q704D1
2r94A Crystal structure of kd(p)ga from t.Tenax (see paper)
25% identity, 73% coverage: 19:236/298 of query aligns to 14:228/286 of 2r94A
Sites not aligning to the query:
O54288 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.55 from Saccharolobus solfataricus (Sulfolobus solfataricus) (see 2 papers)
26% identity, 71% coverage: 8:218/298 of query aligns to 5:211/294 of O54288
Sites not aligning to the query:
5ktlA Dihydrodipicolinate synthase from the industrial and evolutionarily important cyanobacteria anabaena variabilis. (see paper)
27% identity, 94% coverage: 8:287/298 of query aligns to 9:289/295 of 5ktlA
6g3zA Sulfolobus sulfataricus 2-keto-3-deoxygluconate (kdg) aldolase complex with d-kdpg (see paper)
26% identity, 71% coverage: 8:218/298 of query aligns to 4:210/293 of 6g3zA
>WP_014149056.1 NCBI__GCF_000968535.2:WP_014149056.1
MIQLHGPIVALLTPFDASGKIEWQAFKAYLSSLYSWGVRTVIANGTTGEFPSITIRERRQ
VVEFVREYFAGTIINNVSATCVSDVRKLIAGTKGCADYILLLPPYYYSACQDRGLSRFFI
DAISGAPLPAMLYHFPQHTGNHLGIDLVTTLLDQGLSIVGIKDSSGDIDNAQLYRSNFPE
LAVFLGNDAKVFEVLQKGLSGSVTGAANPMPELLIAMQTEYRLSASKTQSMQCCLDVWNR
FRNTGGYSEISLVKAAMGARIDSFPVHVRPPLTPVPVEVIDRIRKVIYNCLNDFRLLN
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory