Comparing WP_015797743.1 NCBI__GCF_000023265.1:WP_015797743.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
D2Z027 O-ureido-L-serine synthase; Cysteine synthase homolog DscD; O-acetylserine sulfhydrylase; EC 2.6.99.3; EC 2.5.1.47 from Streptomyces lavendulae (see paper)
39% identity, 94% coverage: 7:318/331 of query aligns to 5:317/324 of D2Z027
3x43A Crystal structure of o-ureido-l-serine synthase (see paper)
39% identity, 94% coverage: 7:318/331 of query aligns to 4:316/316 of 3x43A
P16703 Cysteine synthase B; CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B; EC 2.5.1.47 from Escherichia coli (strain K12) (see paper)
39% identity, 85% coverage: 13:294/331 of query aligns to 8:288/303 of P16703
3x44A Crystal structure of o-ureido-l-serine-bound k43a mutant of o-ureido- l-serine synthase (see paper)
39% identity, 94% coverage: 7:318/331 of query aligns to 4:316/321 of 3x44A
2bhtA Crystal structure of o-acetylserine sulfhydrylase b (see paper)
38% identity, 85% coverage: 13:294/331 of query aligns to 8:288/294 of 2bhtA
6ahiB Crystal structure of o-acetylserine dependent cystathionine beta- synthase from helicobacter pylori. (see paper)
37% identity, 87% coverage: 8:295/331 of query aligns to 6:302/306 of 6ahiB
2efyA Crystal structure of t.Th. Hb8 o-acetylserine sulfhydrylase complexed with 4-acetylbutyric acid
43% identity, 85% coverage: 12:294/331 of query aligns to 6:297/302 of 2efyA
2ecqA Crystal structure of t.Th. Hb8 o-acetylserine sulfhydrylase complexed with 3-hydroxylactate
43% identity, 85% coverage: 12:294/331 of query aligns to 6:297/302 of 2ecqA
2ecoA Crystal structure of t.Th. Hb8 o-acetylserine sulfhydrylase complexed with 4-methylvalerate
43% identity, 85% coverage: 12:294/331 of query aligns to 6:297/302 of 2ecoA
2q3dA 2.2 a resolution crystal structure of o-acetylserine sulfhydrylase (oass) from mycobacterium tuberculosis in complex with the reaction intermediate alpha-aminoacrylate (see paper)
41% identity, 87% coverage: 6:294/331 of query aligns to 4:301/306 of 2q3dA
P9WP55 O-acetylserine sulfhydrylase; OAS sulfhydrylase; OASS; Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine-specific cysteine synthase; Sulfide-dependent cysteine synthase; EC 2.5.1.47 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
41% identity, 87% coverage: 6:294/331 of query aligns to 4:301/310 of P9WP55
5xoqA Crystal structure of o-acetylserine sulfhydrylase with bound transcription factor peptide inhibitor from planctomyces limnophilus
41% identity, 86% coverage: 11:294/331 of query aligns to 10:302/310 of 5xoqA
4jbnA Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with serine acetyl transferase derived tetrapeptide, spsi (see paper)
38% identity, 87% coverage: 7:294/331 of query aligns to 14:314/336 of 4jbnA
4il5A Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with isoleucine (see paper)
38% identity, 87% coverage: 7:294/331 of query aligns to 14:314/336 of 4il5A
3zeiA Structure of the mycobacterium tuberculosis o-acetylserine sulfhydrylase (oass) cysk1 in complex with a small molecule inhibitor (see paper)
41% identity, 87% coverage: 6:293/331 of query aligns to 4:300/300 of 3zeiA
2q3cA 2.1 a resolution crystal structure of o-acetylserine sulfhydrylase (oass) holoenzyme from mycobacterium tuberculosis in complex with the inhibitory peptide dfsi (see paper)
41% identity, 87% coverage: 6:293/331 of query aligns to 4:300/300 of 2q3cA
4jblB Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with methionine (see paper)
38% identity, 87% coverage: 7:294/331 of query aligns to 14:314/335 of 4jblB
3bm5B Crystal structure of o-acetyl-serine sulfhydrylase from entamoeba histolytica in complex with cysteine (see paper)
38% identity, 87% coverage: 7:294/331 of query aligns to 14:314/335 of 3bm5B
3bm5A Crystal structure of o-acetyl-serine sulfhydrylase from entamoeba histolytica in complex with cysteine (see paper)
38% identity, 87% coverage: 7:294/331 of query aligns to 14:314/338 of 3bm5A
5b1iA Crystal structure of k42a mutant of cystathionine beta-synthase from lactobacillus plantarum in a complex with l-methionine (see paper)
38% identity, 89% coverage: 7:300/331 of query aligns to 4:303/303 of 5b1iA
>WP_015797743.1 NCBI__GCF_000023265.1:WP_015797743.1
MVTGKSQSVLDAIGSTPLIEVEPSIFAKLEYLNPSGSIKARIARYMIEAAEARGELEPGM
TIVEASSGNTGNALAMVAAVKGYRMVVVMPEGLSSERAAISRGFGAEVLRVGNFHVQHAR
ETAVEMGERPGFFCPRQFDSEDNVAENREWLGPEIVTDLGAPPDAFVMGVGTGGTLIGVG
QALRAVNPTTRLVAVEPEESCTILCGEVHHHRIEGIADGFVPTIYERHRTMVDEVIPVTS
LDAVRTMRELARRGMLVGPSSGANLVAARQLREKLGPNATIVTIFADEGEKYLTEYFLTR
GELAAILEGSHDDDWVAASGGITAPLPPLAR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory