Comparing WP_015798095.1 NCBI__GCF_000023265.1:WP_015798095.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P9WP25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
45% identity, 90% coverage: 7:285/309 of query aligns to 12:287/300 of P9WP25
1xxxA Crystal structure of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis (see paper)
45% identity, 90% coverage: 7:285/309 of query aligns to 8:283/296 of 1xxxA
5j5dA Crystal structure of dihydrodipicolinate synthase from mycobacterium tuberculosis in complex with alpha-ketopimelic acid (see paper)
45% identity, 90% coverage: 7:285/309 of query aligns to 9:284/297 of 5j5dA
3l21B The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis - dhdps- a204r
45% identity, 90% coverage: 7:285/309 of query aligns to 7:282/295 of 3l21B
5ktlA Dihydrodipicolinate synthase from the industrial and evolutionarily important cyanobacteria anabaena variabilis. (see paper)
43% identity, 94% coverage: 7:295/309 of query aligns to 5:293/295 of 5ktlA
5ud6C Crystal structure of dhdps from cyanidioschyzon merolae with lysine bound
43% identity, 92% coverage: 7:291/309 of query aligns to 4:292/299 of 5ud6C
1o5kA Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
38% identity, 91% coverage: 12:293/309 of query aligns to 8:291/295 of 1o5kA
Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
38% identity, 91% coverage: 12:293/309 of query aligns to 7:290/294 of Q9X1K9
2atsA Dihydrodipicolinate synthase co-crystallised with (s)-lysine
40% identity, 87% coverage: 7:276/309 of query aligns to 2:271/292 of 2atsA
P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Escherichia coli (strain K12) (see 7 papers)
40% identity, 87% coverage: 7:276/309 of query aligns to 2:271/292 of P0A6L2
5t25A Kinetic, spectral and structural characterization of the slow binding inhibitor acetopyruvate with dihydrodipicolinate synthase from escherichia coli.
40% identity, 87% coverage: 7:276/309 of query aligns to 3:272/293 of 5t25A
3i7sA Dihydrodipicolinate synthase mutant - k161a - with the substrate pyruvate bound in the active site. (see paper)
39% identity, 87% coverage: 7:276/309 of query aligns to 2:271/292 of 3i7sA
4fhaA Structure of dihydrodipicolinate synthase from streptococcus pneumoniae,bound to pyruvate and lysine
37% identity, 88% coverage: 11:281/309 of query aligns to 11:279/307 of 4fhaA
7kg2A Dihydrodipicolinate synthase (dhdps) from c.Jejuni, h59k mutant with pyruvate bound in the active site and l-histidine bound at the allosteric site
36% identity, 87% coverage: 11:280/309 of query aligns to 8:277/296 of 7kg2A
4m19A Dihydrodipicolinate synthase from c. Jejuni with pyruvate bound to the active site and lysine bound to allosteric site (see paper)
36% identity, 87% coverage: 11:280/309 of query aligns to 8:277/296 of 4m19A
4dxvA Crystal structure of dihydrodipicolinate synthase from acinetobacter baumannii complexed with mg and cl ions at 1.80 a resolution
36% identity, 86% coverage: 11:276/309 of query aligns to 6:270/291 of 4dxvA
3u8gA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with oxalic acid at 1.80 a resolution
36% identity, 86% coverage: 11:276/309 of query aligns to 6:270/291 of 3u8gA
3tdfA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 2-ketobutanoic acid at 1.99 a resolution
36% identity, 86% coverage: 11:276/309 of query aligns to 6:270/291 of 3tdfA
3tceA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 5-hydroxylysine at 2.6 a resolution
36% identity, 86% coverage: 11:276/309 of query aligns to 6:270/291 of 3tceA
3rk8A Crystal structure of the chloride inhibited dihydrodipicolinate synthase from acinetobacter baumannii complexed with pyruvate at 1.8 a resolution
36% identity, 86% coverage: 11:276/309 of query aligns to 6:270/291 of 3rk8A
>WP_015798095.1 NCBI__GCF_000023265.1:WP_015798095.1
MAPTVAFGPEITAMATPFGTDGALDLAAAERVARWLVDQGSSAIVVTGSTGESATLSDDE
RATLWRVVAAAVDVPVIAGATTNDTAHSLRLVDAAERAGAKGILAVVPYYNRPPQAGLVR
HFGQIARATSLPVLLYDVPARTGRRLEPETTRELARTSTNVVGLKDASGDLAAAAALVAE
APDGFVLYCGDDALVLPYLAIGAVGVVSVAGHWAGPLQRVMIEAARSGDWERARRLNAAL
EASYRFENQLAYPNPIPTKAMLAALGLAEPVCRSPLIDPTPTLIDEARSVLADLHAQADK
EGIELRVKA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory