Comparing WP_015798110.1 NCBI__GCF_000023265.1:WP_015798110.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 11 hits to proteins with known functional sites (download)
5xoyA Crystal structure of lysk from thermus thermophilus in complex with lysine (see paper)
28% identity, 96% coverage: 3:331/344 of query aligns to 2:323/341 of 5xoyA
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
25% identity, 69% coverage: 15:251/344 of query aligns to 16:274/377 of 7t1qA
Sites not aligning to the query:
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
24% identity, 71% coverage: 5:249/344 of query aligns to 6:272/375 of 4pqaA
Sites not aligning to the query:
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
24% identity, 71% coverage: 5:249/344 of query aligns to 6:272/376 of 4o23A
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
23% identity, 99% coverage: 5:343/344 of query aligns to 7:376/381 of 8uw6B
Sites not aligning to the query:
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
26% identity, 94% coverage: 5:329/344 of query aligns to 13:381/407 of P37111
Sites not aligning to the query:
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
22% identity, 73% coverage: 5:254/344 of query aligns to 6:277/377 of P44514
Sites not aligning to the query:
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
22% identity, 73% coverage: 5:254/344 of query aligns to 10:281/380 of 5vo3A
Sites not aligning to the query:
7lgpB Dape enzyme from shigella flexneri
24% identity, 69% coverage: 5:240/344 of query aligns to 8:264/377 of 7lgpB
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
26% identity, 92% coverage: 12:328/344 of query aligns to 18:364/383 of 7uoiA
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
31% identity, 50% coverage: 46:218/344 of query aligns to 87:276/426 of 3pfoA
Sites not aligning to the query:
>WP_015798110.1 NCBI__GCF_000023265.1:WP_015798110.1
MRDPVELAAAYLEVPSVTGDEAALARLVGEHLDAAGLRVEVVAGCVVARNHGGDSSATLL
VGHLDTVPGELPVAVDELVLRGRGAVDMKAGLAVAVALACSEPSVPVTVVAYPGEEGPIT
GNGLAHLVAERPELLAGARGVLLEPTGGFLELGCQGVVRATLRLRGRRAHVARAWMGRNA
IDRVGEALGTLRALERREPQIGPVRYREAIEVVGVRGGVAWNVVPDLVEIDVSYRFAPDL
DAARARQRLEEAVRPVMDDGDDLEVAEAVPGAVSDLGRFGALRSGAFGVRAKLGWTDVAQ
LVAAGVPAVNFGPGDPELAHTDQEMVEVAEVRHVAQALWRWLHA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory